| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1111/J.1600-065X.1998.TB01442.X |
| P698 | PubMed publication ID | 9602365 |
| P50 | author | Gregory D. Wiens | Q41454582 |
| P2093 | author name string | T O'Hare | |
| M B Rittenberg | |||
| M P Stenzel-Poore | |||
| V A Roberts | |||
| E A Whitcomb | |||
| P2860 | cites work | Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A | Q27728519 |
| X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65 | Q27730538 | ||
| Structural insights into the evolution of an antibody combining site | Q27738883 | ||
| The Protein Data Bank: a computer-based archival file for macromolecular structures | Q27860989 | ||
| Naturally occurring antibodies devoid of light chains | Q28269589 | ||
| On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5. | Q30195996 | ||
| In vitro scanning saturation mutagenesis of an antibody binding pocket | Q30426325 | ||
| Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigen | Q31057169 | ||
| Interactions of protein antigens with antibodies | Q33594252 | ||
| Anatomy of the antibody molecule | Q34060425 | ||
| Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation | Q35939989 | ||
| Clonal nature of the immune response to phosphorylcholine. IV. Idiotypic uniformity of binding site-associated antigenic determinants among mouse antiphosphorylcholine antibodies | Q36273225 | ||
| Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae | Q36346976 | ||
| Glycosylation of a VH residue of a monoclonal antibody against alpha (1----6) dextran increases its affinity for antigen | Q36355288 | ||
| Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin | Q36355399 | ||
| Somatically mutated forms of a major anti-p-azophenylarsonate antibody variable region with drastically reduced affinity for p-azophenylarsonate. By-products of an antigen-driven immune response? | Q36357474 | ||
| Receptor editing in self-reactive bone marrow B cells | Q36361578 | ||
| In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells | Q36362440 | ||
| Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementarity determining region 2. | Q36363581 | ||
| Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen | Q36365350 | ||
| Tracing the development of single memory-lineage B cells in a highly defined immune response | Q36366754 | ||
| Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. | Q36367466 | ||
| Antibody engineering by parsimonious mutagenesis | Q36673572 | ||
| Site-directed mutagenesis of a catalytic antibody: an arginine and a histidine residue play key roles | Q38310601 | ||
| The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme | Q38313296 | ||
| Complementarity, specificity and the nature of epitopes and paratopes in multivalent interactions. | Q40401536 | ||
| Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding | Q41132297 | ||
| Intraclonal generation of antibody mutants in germinal centres | Q41172275 | ||
| Chimeric immunoglobulin light chains are secreted at different levels: influence of framework-1 amino acids | Q41464312 | ||
| Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine | Q41740716 | ||
| Kinetic maturation of an immune response | Q42018143 | ||
| Sequence changes at the V-D junction of the VH1 heavy chain of anti-phosphocholine antibodies alter binding to and protection against Streptococcus pneumoniae | Q42549153 | ||
| Mapping and modification of an antibody hapten binding site: a site-directed mutagenesis study of McPC603. | Q44190075 | ||
| Thermodynamic analysis of an antibody functional epitope | Q46460317 | ||
| Maturation of the immune response in germinal centers | Q48194763 | ||
| Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses | Q48348065 | ||
| Secretion of a lambda 2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region | Q48398642 | ||
| Clonal restriction of the immune response to phosphorylcholine | Q50231869 | ||
| In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. | Q52192552 | ||
| Somatic hypermutation in B cells: an optimal control treatment. | Q52390653 | ||
| Sequence statistics reliably predict stabilizing mutations in a protein domain | Q56903911 | ||
| The Imprint of Somatic Hypermutation on the Repertoire of Human Germline V Genes | Q57444253 | ||
| Mechanism of antigen-driven selection in germinal centres | Q59072211 | ||
| Affinity maturation leads to differential expression of multiple copies of a κ light-chain transgene | Q60065187 | ||
| Structural basis for the specificity of phosphorylcholine-binding immunoglobulins | Q67531932 | ||
| The structure of pneumococcal lipoteichoic acid. Improved preparation, chemical and mass spectrometric studies | Q68011281 | ||
| Affinity labeling of a phosphorylcholine binding mouse myeloma protein | Q70450613 | ||
| Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis | Q71046937 | ||
| Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing | Q71457193 | ||
| V(D)J recombinase activity in a subset of germinal center B lymphocytes | Q73763201 | ||
| The molecular evolution of the immune response | Q85702396 | ||
| P304 | page(s) | 197-209 | |
| P577 | publication date | 1998-04-01 | |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | Harmful somatic mutations: lessons from the dark side | |
| P478 | volume | 162 |
| Q73280962 | A spatial model of germinal center reactions: cellular adhesion based sorting of B cells results in efficient affinity maturation |
| Q36845671 | AID-initiated purposeful mutations in immunoglobulin genes |
| Q41656698 | Computationally driven antibody engineering enables simultaneous humanization and thermostabilization. |
| Q37659557 | How antibodies fold |
| Q42064439 | Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles |
| Q33926461 | Molecular insights into the immunopathogenesis of follicular lymphoma |
| Q52992155 | Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection. |
| Q31108737 | Regulating the isotypic and idiotypic profile of an anti-PC antibody response: lessons from peptide mimics |
| Q44432132 | Repertoire Shift in the Humoral Response to Phosphocholine-Keyhole Limpet Hemocyanin: VH Somatic Mutation in Germinal Center B Cells Impairs T15 Ig Function |
| Q51070881 | Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2α phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic. |
| Q35552528 | Somatic hypermutation patterns in germinal center B cell malignancies |
| Q27624954 | The structural basis of repertoire shift in an immune response to phosphocholine |
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