| human | Q5 |
| P734 | family name | Christ | Q1077956 |
| Christ | Q1077956 | ||
| Christ | Q1077956 | ||
| P735 | given name | Frauke | Q1451934 |
| Frauke | Q1451934 | ||
| P106 | occupation | researcher | Q1650915 |
| Q42772106 | 2-hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: influence of the alkylation of position 4. |
| Q39504985 | 4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process |
| Q42232272 | A new potential approach to block HIV-1 replication via protein-protein interaction and strand-transfer inhibition |
| Q46640952 | A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series |
| Q28483813 | A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication |
| Q39605911 | A versatile and practical synthesis toward the development of novel HIV-1 integrase inhibitors |
| Q35600919 | Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression |
| Q28290761 | Cellular co-factors of HIV-1 integration |
| Q42277905 | Cellular cofactors of lentiviral integrase: from target validation to drug discovery |
| Q45883578 | Characterization of rare lens epithelium-derived growth factor/p75 genetic variants identified in HIV-1 long-term nonprogressors |
| Q38963500 | Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase |
| Q36465556 | Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity |
| Q39140673 | Design of cell-permeable stapled peptides as HIV-1 integrase inhibitors |
| Q39909250 | Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain |
| Q39346109 | Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity |
| Q45157847 | Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors |
| Q33292744 | Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75. |
| Q42226700 | Diketoacid chelating ligands as dual inhibitors of HIV-1 integration process |
| Q35684884 | Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75. |
| Q42273616 | Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction |
| Q39212927 | Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions |
| Q42719255 | Discovery of small molecule HIV-1 integrase dimerization inhibitors |
| Q39902184 | Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions |
| Q40457748 | Dynamic Oligomerization of Integrase Orchestrates HIV Nuclear Entry |
| Q39850377 | Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors |
| Q42716907 | Fragment hopping approach directed at design of HIV IN-LEDGF/p75 interaction inhibitors |
| Q39187770 | Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction |
| Q43714820 | HIV-1 integrase inhibition: looking at cofactor interactions |
| Q34158634 | HIV-1 integrase strand-transfer inhibitors: design, synthesis and molecular modeling investigation |
| Q38306095 | Host factors for retroviral integration site selection |
| Q36298318 | Identification of residues in the C-terminal domain of HIV-1 integrase that mediate binding to the transportin-SR2 protein |
| Q24321722 | Identification of the LEDGF/p75 binding site in HIV-1 integrase |
| Q64086928 | Impact of LEDGIN treatment during virus production on residual HIV-1 transcription |
| Q37855883 | In search of second-generation HIV integrase inhibitors: targeting integration beyond strand transfer |
| Q37350544 | In search of small molecules blocking interactions between HIV proteins and intracellular cofactors |
| Q38333373 | In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75. |
| Q47554259 | Inhibitors of the integrase-transportin-SR2 interaction block HIV nuclear import |
| Q43454997 | Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis |
| Q42318282 | Insight into HIV-2 latency may disclose strategies for a cure for HIV-1 infection |
| Q46458488 | Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication |
| Q24295223 | Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2) |
| Q34586080 | Interplay between HIV entry and transportin-SR2 dependency |
| Q39956082 | Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors |
| Q35770636 | Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation |
| Q34186964 | LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs |
| Q37035177 | LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV |
| Q41454699 | LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions |
| Q38199193 | LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014). |
| Q39879606 | Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ. |
| Q34621545 | Lentiviral nuclear import: a complex interplay between virus and host |
| Q38862441 | Lessons Learned: HIV Points the Way Towards Precision Treatment of Mixed-Lineage Leukemia |
| Q39583211 | Magnesium chelating 2-hydroxyisoquinoline-1,3(2H,4H)-diones, as inhibitors of HIV-1 integrase and/or the HIV-1 reverse transcriptase ribonuclease H domain: discovery of a novel selective inhibitor of the ribonuclease H function |
| Q39680274 | New chloro,fluorobenzylindole derivatives as integrase strand-transfer inhibitors (INSTIs) and their mode of action |
| Q42272892 | New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: virtual screening and activity assays |
| Q39414408 | Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity |
| Q41723437 | Optimization of rhodanine scaffold for the development of protein-protein interaction inhibitors |
| Q39320408 | Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication |
| Q33476232 | Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75. |
| Q36803913 | Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors |
| Q45875738 | Protein-protein and protein-chromatin interactions of LEDGF/p75 as novel drug targets |
| Q40613330 | Rational Design, Synthesis and Evaluation of Coumarin Derivatives as Protein-protein Interaction Inhibitors |
| Q27661671 | Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication |
| Q36747516 | Single-cell imaging of HIV-1 provirus (SCIP). |
| Q45586245 | Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor |
| Q39337204 | Small-molecule inhibitors of the LEDGF/p75 binding site of integrase block HIV replication and modulate integrase multimerization |
| Q27684280 | Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran |
| Q42283539 | Synthesis and biological evaluation of novel antiviral agents as protein-protein interaction inhibitors |
| Q59070555 | Synthesis of new pyridazine derivatives as potential anti-HIV-1 agents |
| Q38577612 | Targeting Virus-host Interactions of HIV Replication |
| Q37471791 | Targeting the HIV integration process in antiviral therapy |
| Q26849265 | The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy |
| Q38329721 | The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding |
| Q39406654 | The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity |
| Q24538808 | Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus |
| Q45879860 | Transportin-SR2 imports HIV into the nucleus |
| Q33280633 | Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV. |
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