Abstract is: Steven J. Burakoff is a cancer specialist and the author of both Therapeutic Immunology (2001) and Graft-Vs.-Host Disease: Immunology, Pathophysiology, and Treatment (1990). He served as Director of The Tisch Cancer Institute at Mount Sinai (2007-2017), which was created in 2007 to focus on translational medicine. He is the Lillian and Henry M. Stratton Professor of Cancer Medicine at Mount Sinai Medical Center as well as Dean for Cancer Innovation and Chief, Pediatric Oncology at the Icahn School of Medicine.
| human | Q5 |
| P646 | Freebase ID | /m/037b9cz |
| P214 | VIAF ID | 65596119 |
| P166 | award received | American Association of Immunologists Lifetime Achievement Award | Q56667085 |
| P27 | country of citizenship | United States of America | Q30 |
| P1343 | described by source | BEIC Digital Library | Q51955019 |
| P69 | educated at | Harvard Medical School | Q49121 |
| Albany Medical College | Q4709349 | ||
| Lehigh University | Q622137 | ||
| Queens College | Q1760438 | ||
| P735 | given name | ??? | Q17501985 |
| ??? | Q17501985 | ||
| P106 | occupation | academic | Q3400985 |
| P21 | sex or gender | male | Q6581097 |
| Q70233176 | 54 Use of the HLA-DR antigens incorporated into liposomes to generate HLA-DR specific cytotoxic T lymphocytes |
| Q34575935 | A CD8/Lck transgene is able to drive thymocyte differentiation |
| Q70997463 | A DC-specific cytolytic T lymphocyte line is OKT8+1 |
| Q34436541 | A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains |
| Q37139072 | A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen |
| Q43896115 | A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation. |
| Q40118503 | A molecular analysis of the cytolytic T lymphocyte response |
| Q57245426 | A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins |
| Q30968615 | A peptide library approach identifies a specific inhibitor for the ZAP-70 protein tyrosine kinase |
| Q99208855 | A perspective on HPK1 as a novel immuno-oncology drug target |
| Q48295813 | A remembrance of Baruj Benacerraf (AAI '57) 1920-2011. |
| Q72073799 | A role for calcineurin in degranulation of murine cytotoxic T lymphocytes |
| Q34547371 | Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones. |
| Q36369244 | Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant |
| Q68885294 | Acute cutaneous graft-versus-host disease to minor histocompatibility antigens in a murine model. Evidence that large granular lymphocytes are effector cells in the immune response |
| Q68121252 | Acute graft-versus-host disease: pathogenesis and prevention with a monoclonal antibody in vivo |
| Q34044528 | Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase |
| Q68858931 | Adhesion of T lymphocytes to human endothelial cells is regulated by the LFA-1 membrane molecule |
| Q40626247 | Adhesion receptors in lymphocyte activation. |
| Q41813849 | Alkylating HIV-1 Nef - a potential way of HIV intervention |
| Q43628300 | Alloreactive lymphocytes from T cell receptor (beta-chain) transgenic mice do not mediate a graft-versus-host reaction |
| Q34319875 | Alloreactivity studied with mutants of HLA-A2. |
| Q37610756 | Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer. |
| Q68944263 | Alpha and beta subunits of the LFA-1 membrane molecule are involved in human monocyte-endothelial cell adhesion |
| Q69070383 | Alpha particle radio-immunotherapy: animal models and clinical prospects |
| Q70302624 | Amelioration of acute graft vs host disease due to minor histocompatibility antigens by in vivo administration of anti-interleukin 2 receptor antibody |
| Q69932980 | Analysis of CD4 and CD2 receptor function |
| Q41542915 | Analysis of cross-reactive antigen-specific T cell clones. Specific recognition of two major histocompatibility complex (MHC) and two non-MHC antigens by a single clone |
| Q71590469 | Analysis of the two-signal requirement for precursor cytolytic T lymphocyte activation using H-2Kk in liposomes |
| Q73241993 | Antigen-induced unresponsiveness results in altered T cell signaling |
| Q35331741 | Antigen-presenting cell function in induction of helper T cells for cytotoxic T-lymphocyte responses: evidence for antigen processing |
| Q72656936 | Antigen-specific suppression of cytotoxic T cell responses: an idiotype-bearing factor regulates the cytotoxic T cell response to azobenzenearsonate-coupled cells |
| Q68090323 | B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes |
| Q70987088 | Basic science seminar: cytotoxic T-lymphocyte response to HLA antigens |
| Q70825933 | Binding affinities of tyrosine-phosphorylated peptides to the COOH-terminal SH2 and NH2-terminal phosphotyrosine binding domains of Shc |
| Q36912528 | Biochemical and functional analyses of a secreted H-2Ld molecule |
| Q68468190 | Biodistribution studies of anti-Thy 1.2 IgM immunoconjugates: Implications for radioimmunotherapy |
| Q35996507 | Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells |
| Q39453411 | Bone marrow transplantation: the genetic and cellular basis of resistance to engraftment and acute graft-versus-host disease |
| Q30192784 | CD4 and signal transduction. |
| Q34360387 | CD4 phosphorylation partially reverses Nef down-regulation of CD4. |
| Q40621045 | CD4, CD8 and CD2 in T cell adhesion and signaling. |
| Q42552884 | CD43 regulates the threshold for T cell activation by targeting Cbl functions |
| Q24296934 | CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1 |
| Q28141639 | CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes |
| Q30176770 | CD43-specific activation of T cells induces association of CD43 to Fyn kinase |
| Q36364664 | CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity |
| Q28343161 | CPF-DD is an inhibitor of infection by human immunodeficiency virus and other enveloped viruses in vitro |
| Q68929339 | CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction |
| Q28316169 | Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A |
| Q34509180 | Calcineurin regulation of the mammalian G0/G1 checkpoint element, cyclin dependent kinase 4. |
| Q82592184 | Cancer therapy from bench to bedside |
| Q70462605 | Cell-mediated cytotoxicity. An overview |
| Q40286668 | Cell-mediated immunity to viral glycoproteins. |
| Q72092822 | Cellular interactions in the generation of cytolytic T lymphocyte responses. Analysis of the helper T cell pathway |
| Q36411721 | Cellular interactions in the generation of cytolytic T lymphocyte responses: role of Ia-positive splenic adherent cells in presentation in H-2 antigen |
| Q72093925 | Cellular interactions in the regulation of the cytolytic T-lymphocyte response: the effect of suboptimal antigen dose |
| Q36552908 | Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells |
| Q28609054 | Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation |
| Q70502482 | Coexpression of the human HLA-A2 or HLA-B7 heavy chain gene and human beta 2-microglobulin gene in L cells |
| Q41050383 | Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase |
| Q60717122 | Construction, expression and recognition of an H—2 molecule lacking its carboxyl terminus |
| Q40374540 | Coreceptors and adapter proteins in T-cell signaling |
| Q44111864 | Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas |
| Q30193645 | Crk interacts with tyrosine-phosphorylated p116 upon T cell activation |
| Q36360117 | Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells |
| Q42521733 | Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: histologic analysis and correlation to clinical disease |
| Q73086137 | Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling |
| Q40492290 | Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. |
| Q72111694 | Cytolytic T lymphocyte recognition of subcellular antigen |
| Q45795150 | Cytolytic T lymphocyte response to Moloney sarcoma virus |
| Q34632083 | Cytolytic pathways in haematopoietic stem-cell transplantation |
| Q28141661 | Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation |
| Q40118391 | Cytotoxic T cells directed against HLA-DR antigens and their surface proteins. |
| Q44808415 | Cytotoxic T lymphocyte recognition of class I H-2 antigens after DNA-mediated gene transfer. |
| Q42820569 | Cytotoxic T lymphocyte recognition of transfected cells expressing a cloned retroviral gene |
| Q36335741 | Cytotoxic T lymphocytes induced against allogeneic I-region determinants react with Ia molecules on trinitrophenyl-conjugated syngeneic target cells |
| Q36335401 | Cytotoxic T lymphocytes specific for I region determinants do not require interactions with H-2K or D gene products |
| Q52617496 | Determination of junction avidity of cytolytic T cell and target cell. |
| Q36406862 | Development and characterization of allospecific long-term human cytolytic T-cell lines |
| Q51127244 | Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes. |
| Q41634128 | Differential activation of phosphotyrosine protein phosphatase activity in a murine T cell hybridoma by monoclonal antibodies to CD45 |
| Q73785060 | Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect |
| Q34350414 | Direct evidence for a receptor-ligand interaction between the T-cell surface antigen CD2 and lymphocyte-function-associated antigen 3. |
| Q36355855 | Direct evidence for binding of CD8 to HLA class I antigens |
| Q52507544 | Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. |
| Q37154861 | Disruption of the CD4-p56lck complex is required for rapid internalization of CD4 |
| Q38441450 | Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease |
| Q36349303 | Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains |
| Q41718276 | Distinct effects of interferon-gamma and MHC class I surface antigen levels on resistance of the K562 tumor cell line to natural killer-mediated lysis |
| Q41447289 | Distinct roles for L3T4 in T cell activation. |
| Q68106739 | Dynamic changes in viscoelastic properties in cytotoxic T-lymphocyte-mediated killing |
| Q44048428 | Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling |
| Q69735008 | Effect of timing of lymphokine presentation on generation of cytotoxic T lymphocytes |
| Q69919770 | Efficient conjugation of DTPA to an IgM monoclonal antibody in ascites fluid |
| Q68138223 | Engraftment following T cell-depleted bone marrow transplantation. III. Differential effects of increased total-body irradiation on semiallogeneic and allogeneic recipients |
| Q68199382 | Engraftment following T-cell-depleted bone marrow transplantation. II. Stability of mixed chimerism in semiallogeneic recipients after total-body irradiation |
| Q69898957 | Engraftment following T-cell-depleted marrow transplantation. I. The role of major and minor histocompatibility barriers |
| Q34791351 | Enhanced allostimulatory activity of host antigen-presenting cells in old mice intensifies acute graft-versus-host disease |
| Q24303591 | Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome |
| Q28609037 | Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor |
| Q30452658 | Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo |
| Q28610830 | Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling |
| Q36362755 | Evidence for differential intracellular signaling via CD4 and CD8 molecules |
| Q68508969 | Evidence that anti-LFA-1 in vivo improves engraftment and survival after allogeneic bone marrow transplantation |
| Q41885088 | Evidence that anti-asialo GM1 in vivo improves engraftment of T cell-depleted bone marrow in hybrid recipients. |
| Q69482689 | Evidence that large granular lymphocytes of donor origin mediate acute graft-versus-host disease |
| Q72601732 | Experimental evidence for the potential usefulness of permanent IL-3-dependent multipotential hematopoietic progenitor cell lines in transfusion granulocyte support therapy: need for expansion of early passage cells |
| Q45828799 | Expression and CTL recognition of cloned subgenomic fragments of Moloney murine leukemia virus in murine cells |
| Q58974630 | Expression and function of CD4 in a murine T-cell hybridoma |
| Q36354243 | Expression and function of CD8 in a murine T cell hybridoma |
| Q57245427 | Expression and function of a CD 5 cDNA in human and murine T cells |
| Q52507670 | Expression and induction of nuclear factor-kappa B-related proteins in thymocytes. |
| Q53508396 | Expression and ontogeny of CD2 on murine B cells. |
| Q69372557 | Expression and ontogeny of murine CD2 |
| Q54373274 | Expression of CD5 regulates responsiveness to IL-1. |
| Q33554075 | Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation |
| Q35016380 | Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants |
| Q36703177 | FK 506 and rapamycin: molecular probes of T-lymphocyte activation |
| Q41377918 | FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells |
| Q36364570 | FK506 inhibits antigen receptor-mediated induction of c-rel in B and T lymphoid cells |
| Q74087711 | Fas ligand-deficient gld mice are more susceptible to graft-versus-host-disease |
| Q73289694 | Fas-deficient lpr mice are more susceptible to graft-versus-host disease |
| Q34340679 | Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing |
| Q21145672 | From bytes to bedside: data integration and computational biology for translational cancer research |
| Q67654124 | Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3 |
| Q70341752 | Functional T cell deficits after bone marrow transplantation across minor histocompatibility barriers: effects of graft-vs-host disease on precursor frequency of reactive cells |
| Q39531850 | Functional analysis of CD2, CD4, and CD8 in T-cell activation |
| Q68094613 | Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule |
| Q70307336 | Functional assessment of T cell depletion from bone marrow prior to therapeutic transplantation using limiting dilution culture methods |
| Q41484042 | Functional distinctions between the LFA-1, LFA-2, and LFA-3 membrane proteins on human CTL are revealed with trypsin-pretreated target cells. |
| Q43517923 | Functional expression of human CD8 in fully reconstituted mice after retroviral-mediated gene transfer of hemopoietic stem cells |
| Q28299562 | Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions |
| Q37312613 | Generation of cytolytic T lymphocytes after reovirus infection: role of S1 gene |
| Q42936300 | Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice |
| Q52219627 | Generation of long-term human cytolytic cell lines with persistent natural killer activity. |
| Q72079045 | Genetic control of cytolytic T lymphocyte responses. III. The role of K and I region alleles on the specificity of the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells |
| Q36341767 | Genetic control of cytolytic T-lymphocyte responses. I. Ir gene control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells |
| Q36341787 | Genetic control of cytolytic t-lymphocyte responses. II. The role of the host genotype in parental leads to F1 radiation chimeras in the control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells |
| Q45805316 | Genetic control of the cytolytic T lymphocyte response to influenza viruses: H-2 genes influence the response to H-2Kb plus virus |
| Q41674754 | Glycolipid-anchored form of CD4 increases intercellular adhesion but is unable to enhance T cell activation |
| Q58065088 | Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines |
| Q73519073 | Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity |
| Q36211059 | Growth-inhibitory activity of lymphoid cell plasma membranes. II. Partial characterization of the inhibitor |
| Q36890377 | H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells |
| Q34444909 | HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent |
| Q28254561 | HIV-gp120 can block CD4-class II MHC-mediated adhesion |
| Q97422009 | HPK1 Influences Regulatory T Cell Functions |
| Q38000158 | HPK1 as a novel target for cancer immunotherapy |
| Q44274485 | Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription |
| Q42947729 | Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response |
| Q47884382 | Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation |
| Q69909330 | Heritable lymphocyte function-associated antigen-1 deficiency: abnormalities of cytotoxicity and proliferation associated with abnormal expression of LFA-1 |
| Q22010565 | Human 70-kDa SHP-1L differs from 68-kDa SHP-1 in its C-terminal structure and catalytic activity |
| Q70494445 | Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules |
| Q34543228 | Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones |
| Q33656997 | Human immunodeficiency virus infection is efficiently mediated by a glycolipid-anchored form of CD4. |
| Q58065106 | Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity |
| Q58065094 | Human lymphocyte function associated antigens |
| Q36347669 | Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon |
| Q24556587 | Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules |
| Q37519411 | Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation |
| Q28615983 | Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp) |
| Q68812264 | Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures |
| Q70385932 | Immunodeficiency in graft-versus-host disease. I. Mechanism of immune suppression |
| Q40388384 | Immunophilins in protein folding and immunosuppression. |
| Q70569312 | In vitro generation of helper T cells and suppressor T cells that regulate the cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells |
| Q34327765 | Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model |
| Q68554329 | Induction of HLA class I surface expression recruits low-affinity cytolytic T lymphocytes |
| Q37611649 | Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice |
| Q61140933 | Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins |
| Q52230492 | Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens. |
| Q37595163 | Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles |
| Q28281557 | Inhibition of CD4+ T cell function by the HIV envelope protein, gp120 |
| Q35986248 | Inhibition of cell-mediated cytolysis of trinitrophenyl-derivatized target cells by alloantisera directed to the products of the K and D loci of the H-2 complex |
| Q67903035 | Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease |
| Q44750081 | Inhibition of lymphokine-activated killer cell-mediated cytotoxicity by phorbol ester |
| Q70226452 | Inhibition of normal lymphocyte responses by cell membranes |
| Q40680075 | Inhibition of the induction of cytolytic T lymphocytes with alloantisera directed against H-2K and H-2D gene products |
| Q67691867 | Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes |
| Q69824714 | Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation |
| Q28592794 | Interaction of Shc with Grb2 regulates association of Grb2 with mSOS |
| Q71556468 | Interaction of Shc with Grb2 regulates the Grb2 association with mSOS |
| Q41514671 | Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation |
| Q40201690 | Interactions of T lymphocytes with human vascular endothelial cells: role of endothelial cells surface antigens. |
| Q68963617 | Interferon-gamma induction of LFA-1-mediated homotypic adhesion of human monocytes |
| Q34789964 | Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction |
| Q37428787 | Interruption of the sequential release of small and large molecules from tumor cells by low temperature during cytolysis mediated by immune T-cells or complement |
| Q40818619 | Intracellular signaling consequences of anti-IL-2Ralpha blockade by daclizumab |
| Q52519672 | Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase. |
| Q41109029 | Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation. |
| Q45176125 | Ir gene control of the cytotoxic T lymphocyte response to Sendai virus: H-2k mice are low responders to Sendai |
| Q56909038 | Irradiated B7-1 transduced primary acute myelogenous leukemia (AML) cells can be used as therapeutic vaccines in murine AML |
| Q44800235 | Is the primary complement lesion insufficient for lysis? Failure of cells damaged under osmotic protection to lyse in EDTA or at low temperature after removal of osmotic protection |
| Q69892970 | LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes |
| Q43651841 | LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation. |
| Q30453894 | Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness |
| Q36217691 | Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density |
| Q24324441 | Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells |
| Q44272110 | Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling |
| Q24528144 | Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum |
| Q69993136 | Long-lasting deficit of functional T cell precursors in human bone marrow transplant recipients revealed by limiting dilution methods |
| Q36290374 | Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+. |
| Q52511889 | Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease. |
| Q59063739 | Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon |
| Q37637433 | Lymphocytes with a CD4+ CD8- CD3- phenotype are effectors of experimental cutaneous graft-versus-host disease |
| Q41641062 | Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease |
| Q34784600 | Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation |
| Q37328553 | Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni |
| Q68981023 | Mapping functional epitopes of the human LFA-1 glycoprotein: monoclonal antibody inhibition of NK and CTL effectors |
| Q57245404 | Measurement of Calcineurin Phosphatase Activity in Cell Extracts |
| Q46804649 | Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction |
| Q68098713 | Membrane-bound anti-CD3 monoclonal antibodies trigger cytolytic T-lymphocyte-mediated tumor lysis |
| Q33569346 | Molecular and biological actions of cyclosporin A and FK506 on T cell development and function |
| Q33970334 | Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25 |
| Q24321585 | Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13 |
| Q74357215 | Monoallelic expression of the interleukin-2 locus |
| Q35058200 | Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens |
| Q90281775 | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation |
| Q38213138 | Murine CD2: structure, expression, and recognition of human LFA-3. |
| Q38786680 | Mutants of HLA-A2 in the analysis of its structure and function |
| Q28505899 | NFATc2-mediated repression of cyclin-dependent kinase 4 expression |
| Q71163152 | Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny |
| Q34330794 | Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells |
| Q41687189 | Non-MHC-restricted target-cell lysis by a CD4-CD8- TCR alpha beta T-cell line, as well as by TCR gamma delta T-cell lines, results from lymphokine-activated killing |
| Q58960489 | Non-MHC-restricted target-cell lysis by a CD4−CD− TCRαβ T-cell line, as well as by TCR4gMδ T-cell lines, results from lymphokine-activated killing |
| Q39509049 | Non-invasive in vivo imaging for liver tumour progression using an orthotopic hepatocellular carcinoma model in immunocompetent mice |
| Q58960496 | Novel subsets of human T cells (CD4+ CD8+ TCRγδ and CD4− CD8− TCRαβ) and T-cell development |
| Q38366110 | Novel subsets of human T cells (CD4+ CD8- TCR gamma delta and CD4- CD8- TCR alpha beta) and T-cell development |
| Q36364085 | Nuclear factors that mediate intrathymic signals are developmentally regulated |
| Q68082159 | Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction |
| Q70726005 | Phenotypic and functional analysis of expanded natural killer cell subpopulations in Hodgkin's disease patients treated with lymphoid irradiation |
| Q35587741 | Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5. |
| Q59061510 | Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor |
| Q33542715 | Positive and negative signaling pathways |
| Q41727807 | Prevention of HIV-1 infection and preservation of CD4 function by the binding of CPFs to gp120. |
| Q34569267 | Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand |
| Q70226619 | Production of colony-stimulating factor(s) for granulocyte-macrophage and multipotential (granulocyte/erythroid/megakaryocyte/macrophage) hematopoietic progenitor cells (CFU-GEMM) by clonal lines of human IL-2-dependent T-lymphocytes |
| Q30157749 | Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway |
| Q68831195 | Protein kinase C required for cytotoxic T lymphocyte triggering |
| Q69918183 | Radioimmunotherapy with alpha-particle-emitting immunoconjugates |
| Q56551670 | Rapamycin and FK506 binding proteins (immunophilins) |
| Q34271784 | Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity |
| Q40092193 | Recapitulation of the immune response and haematopoietic system in bone marrow transplantation |
| Q37579216 | Recognition of HLA-A2 and -B7 antigens by cloned cytotoxic T lymphocytes after gene transfer into human and monkey, but not mouse, cells |
| Q54492506 | Recognition of HLA-A2 mutant and variant target cells by an HLA-A2 allospecific human cytotoxic T lymphocyte line |
| Q37542897 | Recognition of interspecies hybrid class I histocompatibility antigens by antigen-specific cytolytic T lymphocytes |
| Q60717101 | Recognition of the alpha-1 and alpha-2 domains of H-2 molecules by allospecific cloned T cells |
| Q28140642 | Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells |
| Q54372576 | Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation. |
| Q77123376 | Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibition of protein tyrosine phosphatases |
| Q40934688 | Requirement for Shc in TCR-mediated activation of a T cell hybridoma |
| Q70312940 | Requirement for three distinct lymphokines for the induction of cytotoxic T lymphocytes from thymocytes |
| Q69735860 | Requirements for modulation of the CD4 molecule in response to phorbol myristate acetate. Role of the cytoplasmic domain |
| Q72780161 | Responses to the H–2Kba mutant involve recognition of syngeneic Ia molecules |
| Q68187364 | Retarded recovery of functional T cell frequencies in T cell-depleted bone marrow transplant recipients |
| Q44325114 | Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes |
| Q36350377 | Role of L3T4 in antigen-driven activation of a class I-specific T cell hybridoma |
| Q72109246 | Role of syngeneic Ia+ accessory cells in the generation of allospecific CTL responses |
| Q30176791 | Role of the Lck Src homology 2 and 3 domains in protein tyrosine phosphorylation |
| Q24655178 | SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling |
| Q28771497 | SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness |
| Q71915303 | Severe colitis in mice with aberrant thymic selection |
| Q36352548 | Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation |
| Q72073802 | Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58 |
| Q40364306 | Signaling T-cell survival and death by IL-2 and IL-15. |
| Q36357522 | Site-directed mutagenesis of class I HLA genes. Role of glycosylation in surface expression and functional recognition |
| Q27729434 | Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor |
| Q93536541 | Species-restricted recognition of transfected HLA-A2 and HLA-B7 by human CTL clones |
| Q60717161 | Specificity of OKT4+ cytotoxic T lymphocyte clones |
| Q72074421 | Specificity of alloreactive T lymphocytes that adhere to lung stage schistosomula of Schistosoma mansoni |
| Q72616297 | Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles |
| Q39432355 | Specificity of rat xenogeneic cell-mediated cytolysis for the products of the K and D loci of the mouse H-2 complex |
| Q36345419 | Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses. |
| Q69615160 | Spontaneous aggregation as a mechanism for human monocyte purification |
| Q43567970 | Stimulation of secondary anti-MSV cytolytic T lymphocytes with MBL-2 reconstituted membranes |
| Q34290748 | Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. |
| Q27732196 | Structure and ligand recognition of the phosphotyrosine binding domain of Shc |
| Q27617539 | Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase |
| Q72668130 | Suppression of anti-hapten antibody responses by hapten-specific cytolytic T lymphocytes: role of I-A-associated antigen on target B lymphocytes |
| Q36355375 | Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor |
| Q28272069 | T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activation |
| Q39224258 | T cell adhesion molecules |
| Q45840408 | T cell hybridomas define the class II MHC-restricted response to vesicular stomatitis virus infection |
| Q37713219 | T cell receptors: adhesion and signaling |
| Q41639774 | T cell surface molecules regulating noncognate B lymphocyte activation. Role of CD2 and LFA-1. |
| Q42242584 | T lymphocyte-mediated suppression of myeloma function in vitro. II. Evidence for regulation of hapten-binding myelomas by syngeneic hapten-specific cytolytic T lymphocytes |
| Q42031600 | T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes |
| Q34317330 | T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation |
| Q38212228 | T-lymphocyte activation: the biology and function of CD2 and CD4. |
| Q69383680 | T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition |
| Q32133379 | Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation |
| Q24561774 | The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin |
| Q36229834 | The CD4 molecule is not always required for the T cell response to bacterial enterotoxins |
| Q90865142 | The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before |
| Q69977148 | The ability of Ia and H-2Kk-bearing membranes to replace the antigen-presenting cell in an H-2Kk allogeneic cytotoxic T cell response |
| Q28258982 | The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation |
| Q43885528 | The alpha-3 domain of class I MHC proteins influences cytotoxic T lymphocyte recognition of antigenic determinants located within the alpha-1 and alpha-2 domains |
| Q38624492 | The biologic roles of CD2, CD4, and CD8 in T-cell activation |
| Q36342063 | The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens |
| Q41369763 | The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. |
| Q39558723 | The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. I. Evidence for antigen-specific helper T cells |
| Q39558731 | The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. II. Evidence for antigen-specific suppressor T cells |
| Q41731525 | The cytoplasmic domain of CD4 is required for stable association with the lymphocyte-specific tyrosine protein kinase p56lck |
| Q41029821 | The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development. |
| Q28323723 | The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation |
| Q77298460 | The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells |
| Q69907269 | The function of LFA-1 in cell-mediated killing and adhesion: studies on heritable LFA-1, Mac-1 deficiency and on lymphoid cell self-aggregation |
| Q58065114 | The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions |
| Q68974028 | The human HLA-specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the alpha 2 domain of murine H-2Db |
| Q45831290 | The immune response to Moloney murine leukemia virus-induced tumors: induction of cytolytic T lymphocytes specific for both viral and tumor-associated antigens |
| Q39484149 | The induction of cytolytic T lymphocytes with purified plasma membranes |
| Q39511233 | The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells |
| Q40712575 | The induction of cytolytic T lymphocytes with syngeneic trinitrophenyl-coupled membranes |
| Q36340066 | The induction of secondary cytolytic T lymphocytes by solubilized membrane proteins |
| Q36342189 | The induction of virus-specific cytotoxic T lymphocytes with solubilized viral and membrane proteins |
| Q37296722 | The interaction of CD4 with HIV-1 gp120. |
| Q70012319 | The mechanism of antigen presentation by dendritic cells and splenic adherent cells in the induction of an allogeneic cytotoxic T-lymphocyte response to H-2Kk liposomes |
| Q72847300 | The origins of alloreactivity: differentiation of prekiller cells to viral infection results in alloreactive cytolytic T lymphocytes |
| Q41746506 | The regulation of exogenous and endogenous class I MHC genes in a human tumor cell line, K562. |
| Q69922042 | The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity |
| Q70340054 | The role of L3T4 (CD4) in T-cell activation |
| Q36348681 | The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma |
| Q68955490 | The role of T cell accessory molecules in the generation of class II-specific xenogeneic cytolytic T cells |
| Q34038122 | The role of calcineurin in lymphocyte activation |
| Q39481794 | The role of functional cell surface antigens in T cell activation |
| Q44807312 | The role of the L3T4 molecule in mitogen and antigen-activated signal transduction |
| Q33776788 | The small GTP-binding protein Rho potentiates AP-1 transcription in T cells |
| Q24628750 | Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3 |
| Q69857367 | Thy-1 is a differentiation antigen that characterizes immature murine erythroid and myeloid hematopoietic progenitors |
| Q72812929 | Thymectomized, irradiated, and bone marrow-reconstituted chimeras have normal cytolytic T lymphocyte precursors but a defect in lymphokine production |
| Q72608605 | Transplantation. Antigen, co-stimulators and cytokines: regulators of allogeneic interactions |
| Q33911404 | Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin |
| Q45367448 | Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis. |
| Q36442603 | Type-specific reovirus antiserum blocks the cytotoxic T-cell-target cell interaction: evidence for the association of the viral hemagglutinin of a nonenveloped virus with the cell surface |
| Q36732179 | Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation |
| Q30176911 | Tyrosine-phosphorylated Cbl binds to Crk after T cell activation. |
| Q32024520 | Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes |
| Q60717094 | Viral restricted cytolytic T lymphocyte recognition of hybrid human-murine class I histocompatibility antigens |
| Q52122062 | Wnt-1 and Wnt-4 regulate thymic cellularity. |
| Q68053591 | p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation |
| Steven J. Burakoff | wikipedia |
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