| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0035-3787(04)70845-0 |
| P698 | PubMed publication ID | 14978392 |
| P2093 | author name string | V Meininger | |
| A Muller | |||
| L Dupuis | |||
| J P Loeffler | |||
| P2860 | cites work | Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1 | Q22299419 |
| A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2 | Q24291755 | ||
| Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis | Q24306886 | ||
| Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Q28131805 | ||
| The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis | Q28190263 | ||
| Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis | Q28203381 | ||
| Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury | Q28511628 | ||
| Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q28585525 | ||
| Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions | Q28591963 | ||
| Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS | Q28610671 | ||
| Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation | Q29547561 | ||
| Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis | Q32063679 | ||
| Familial amyotrophic lateral sclerosis | Q34547620 | ||
| Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis | Q34718757 | ||
| Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis | Q34736976 | ||
| Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1 | Q35425101 | ||
| Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis | Q35580300 | ||
| Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase | Q36270615 | ||
| Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superox | Q36662645 | ||
| Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis. | Q38291855 | ||
| Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice: animal model of gene dosage effects in Down's syndrome | Q41140051 | ||
| Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis | Q41237348 | ||
| Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons | Q41644415 | ||
| Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. | Q43547870 | ||
| Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis | Q43569621 | ||
| A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group | Q43683334 | ||
| Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results. | Q43777132 | ||
| Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients | Q43883813 | ||
| High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation | Q43918294 | ||
| Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice | Q43977943 | ||
| Minocycline delays disease onset and mortality in a transgenic model of ALS. | Q44024931 | ||
| Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site | Q44070818 | ||
| Survival in transgenic ALS mice does not vary with CNS glutathione peroxidase activity. | Q44131398 | ||
| Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. | Q45877621 | ||
| ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. | Q46135324 | ||
| Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase | Q46566731 | ||
| Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis | Q48266693 | ||
| Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. | Q48874060 | ||
| A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections. | Q50501359 | ||
| Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice. | Q51714635 | ||
| Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. | Q52546347 | ||
| Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants. | Q52908162 | ||
| An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria | Q54965159 | ||
| Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. | Q55032889 | ||
| Inhibition of ICE slows ALS in mice | Q59081638 | ||
| Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model | Q60144092 | ||
| Familial adult motor neuron disease: amyotrophic lateral sclerosis | Q70035464 | ||
| Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis | Q70633178 | ||
| Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis | Q70958165 | ||
| A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group | Q72759362 | ||
| Blood oxidative stress in amyotrophic lateral sclerosis | Q73039021 | ||
| Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in G86R superoxide dismutase transgenic mice | Q73219169 | ||
| A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo-neurohypophysial axis | Q73265105 | ||
| Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase | Q73316561 | ||
| Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration | Q73348009 | ||
| A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis | Q73440820 | ||
| Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q73520806 | ||
| Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis | Q73907503 | ||
| Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal cord motor neurons | Q74240941 | ||
| Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis: evidence for the implication of the p53 signaling pathway | Q74240982 | ||
| Early and selective pathology of light chain neurofilament in the spinal cord and sciatic nerve of G86R mutant superoxide dismutase transgenic mice | Q74332165 | ||
| Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease | Q74334654 | ||
| Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis | Q74411605 | ||
| Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1 | Q74454204 | ||
| CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations | Q74625760 | ||
| Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS | Q74733872 | ||
| The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis | Q77107922 | ||
| Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading | Q77754821 | ||
| P433 | issue | 1 | |
| P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
| P304 | page(s) | 35-43 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Revue neurologique | Q7318987 |
| P1476 | title | [Molecular mechanisms of amyotrophic lateral sclerosis: recent contributions from studies in animal models] | |
| P478 | volume | 160 |
| Q38160421 | Amyotrophic lateral sclerosis and skeletal muscle: an update. |
| Q33294971 | Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. |
| Q47155349 | Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice |
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