Age-associated alterations in calcium current and its modulation in cardiac myocytes

scientific article published on 01 August 1998

Age-associated alterations in calcium current and its modulation in cardiac myocytes is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1004433915
P356DOI10.2165/00002512-199813020-00007
P698PubMed publication ID9739504

P2093author name stringE G Lakatta
R P Xiao
Y Y Zhou
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Differential alterations in ATP-supported calcium transport activities of sarcoplasmic reticulum and sarcolemma of aging myocardiumQ72514552
CaMKII is responsible for activity-dependent acceleration of relaxation in rat ventricular myocytesQ72564947
Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytesQ72577762
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Phosphorylation of the L-type calcium channel beta subunit is involved in beta-adrenergic signal transduction in canine myocardiumQ72638208
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Calcium current is increased in isolated adult myocytes from hypertrophied rat myocardiumQ41265301
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Alterations in the properties of β-adrenergic receptors of myocardial membranes in aging: Impairments in agonist—receptor interactions and guanine nucleotide regulation accompany diminished catecholamine-responsiveness of adenylated cyclaseQ42452289
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The cellular basis for the blunted response to beta-adrenergic stimulation in supraventricular tachycardia-induced cardiomyopathyQ42503620
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Low-threshold current is major calcium current in chick ventricle cellsQ45105485
Reduced calcium current density in single myocytes isolated from hypertrophied failing guinea pig heartsQ46168535
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Effects of various intracellular Ca ion concentrations on the calcium current of guinea-pig single ventricular cellsQ46417615
Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytesQ46473208
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Increase of the delayed rectifier K+ and Na(+)-K+ pump currents by hypotonic solutions in guinea pig cardiac myocytesQ46771581
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Differences in isoproterenol stimulation of Ca2+ current of rat ventricular myocytes in neonatal compared to adult.Q52198028
Developmental changes in the actions of phosphatase inhibitors on calcium current of rabbit heart cells.Q52215869
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Relationship between behavioral and motor responses of mature and old mice and cerebellar beta-adrenergic receptor density.Q54119661
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Action potential and plateau ionic currents in moderately and severely DOCA-salt hypertrophied rat heartsQ64038872
Ionic basis of the action potential prolongation in ventricular myocytes from Syrian hamsters with dilated cardiomyopathyQ64038882
Diminished inotropic response of aged myocardium to catecholaminesQ66912813
Endothelin-1 enhances calcium entry through T-type calcium channels in cultured neonatal rat ventricular myocytesQ67504160
Voltage dependence of contraction and calcium current in severely hypertrophied feline ventricular myocytesQ67904164
Calcium current in congestive heart failure of hamster cardiomyopathyQ67914914
Immunodetectable levels of the inhibitory guanine nucleotide-binding regulatory proteins in failing human heart: discordance with measurements of adenylate cyclase activity and levels of pertussis toxin substrateQ68045188
Calcium current in single cells isolated from normal and hypertrophied rat heart. Effects of beta-adrenergic stimulationQ68091255
Forskolin activation of adenylate cyclase in rat myocardium with age: effects of guanine nucleotide analogsQ68752938
Effects of aging on phospholamban phosphorylation and calcium transport in rat cardiac sarcoplasmic reticulumQ68845115
Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathwayQ69351588
Calcium currents in normal and hypertrophied isolated feline ventricular myocytesQ69845164
P433issue2
P304page(s)159-171
P577publication date1998-08-01
P1433published inDrugs & AgingQ5308946
P1476titleAge-associated alterations in calcium current and its modulation in cardiac myocytes
P478volume13

Reverse relations

cites work (P2860)
Q37766138Advances in gene-based therapy for heart failure
Q80062832Age and QT variability index during free breathing, controlled breathing and tilt in patients with chronic heart failure and healthy control subjects
Q50048281Calcium current properties in dystrophin-deficient ventricular cardiomyocytes from aged mdx mice
Q39144763Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets
Q36723709Mechanisms of arrhythmias and conduction disorders in older adults
Q42248990Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation
Q58574774Voltage-Dependent Sarcolemmal Ion Channel Abnormalities in the Dystrophin-Deficient Heart