Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments

scientific article published on 01 November 2002

Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0736-0266(02)00070-0
P698PubMed publication ID12472239

P50authorMichael D. BuschmannQ39680614
P2093author name stringMarc Thibault
A Robin Poole
P2860cites workIncreased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassayQ34140878
Contact pressures in the human hip joint measured in vivoQ35602398
Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degenerationQ35768757
Cartilage and diarthrodial joints as paradigms for hierarchical materials and structuresQ35929844
Swelling and fibronectin accumulation in articular cartilage explants after cyclical impactQ36804399
Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilageQ37365557
Evidence for altered synthesis of type II collagen in patients with osteoarthritisQ37388249
Insights into the natural history of osteoarthritis provided by the cruciate-deficient dog. An animal model of osteoarthritisQ40642325
Impact-induced fissuring of articular cartilage: an investigation of failure criteriaQ40805128
A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.Q50936554
A fibril reinforced nonhomogeneous poroelastic model for articular cartilage: inhomogeneous response in unconfined compression.Q52073544
A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics.Q52342637
Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants.Q52481664
Matrix damage and chondrocyte viability following a single impact load on articular cartilage.Q52508189
Articular cartilage deformation under physiological cyclic loading--apparatus and measurement technique.Q52868222
The Chondrocyte Cytoskeleton in Mature Articular Cartilage: Structure and Distribution of Actin, Tubulin, and Vimentin FilamentsQ59285731
Mature Full-thickness Articular Cartilage Explants Attached to Bone are Physiologically Stable over Long-term Culture in Serum-free MediaQ59285743
Partial restoration of immobilization-induced softening of canine articular cartilage after remobilization of the knee (stifle) jointQ69581548
Swelling of articular cartilage and other connective tissues: electromechanochemical forcesQ70113832
Proteolytic enzymes as probes for the triple-helical conformation of procollagenQ70151437
Experimental osteoarthritis in dogs: a comparison of the Pond-Nuki and medial arthrotomy methodsQ71325330
Clinical correlations of osteoarthritis associated with a single-base mutation (arginine519 to cysteine) in type II procollagen gene. A newly defined pathogenesisQ72296661
Changes in cartilage composition and physical properties due to stromelysin degradationQ72526689
Differences in type II collagen degradation between peripheral and central cartilage of rat stifle joints after cranial cruciate ligament transectionQ73028073
The increased swelling and instantaneous deformation of osteoarthritic cartilage is highly correlated with collagen degradationQ73092708
Effect of impact load on articular cartilage: development of an intra-articular fracture modelQ73691274
Detection and analysis of cartilage degeneration by spatially resolved streaming potentialsQ74590997
Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explantsQ77331710
A fibril-network-reinforced biphasic model of cartilage in unconfined compressionQ77970748
Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependentQ93929148
P433issue6
P304page(s)1265-1273
P577publication date2002-11-01
P1433published inJournal of Orthopaedic ResearchQ6295700
P1476titleCyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments
P478volume20

Reverse relations

cites work (P2860)
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