Establishing the inhibitory effects of bradykinin on thrombin

scientific article published on 01 February 2003

Establishing the inhibitory effects of bradykinin on thrombin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0003-9861(02)00677-X
P698PubMed publication ID12559981

P2093author name stringMuriel C Maurer
William D Ehringer
David B Cleary
P2860cites workCloning and characterization of human protease-activated receptor 4Q24322941
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationQ24337851
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombinQ24563384
The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationshipsQ27642041
Examining thrombin hydrolysis of the factor XIII activation peptide segment leads to a proposal for explaining the cardioprotective effects observed with the factor XIII V34L mutationQ28115016
Thrombostatin, a bradykinin metabolite, reduces platelet activation in a model of arterial wall injuryQ28192655
A dual thrombin receptor system for platelet activationQ28280578
Thrombin signalling and protease-activated receptorsQ29619601
Interaction of bradykinin with angiotensin, prostacyclin, and nitric oxide in myocardial preservationQ33692456
How the protease thrombin talks to cellsQ33740137
Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1.Q33900013
Protease activated receptors: theme and variationsQ34225983
Determinants of thrombin specificity.Q34311776
Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylationQ36235851
Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact plateletsQ38306581
Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombinQ40876061
A player of many parts: the spotlight falls on thrombin's structure.Q40893212
Protein kinase C phosphorylates caldesmon77 and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayersQ41110801
Increase of bradykinin in plasma of patients undergoing cardiopulmonary bypass: the importance of lung exclusion.Q42514115
Structural and functional mapping of the thrombin domain involved in the binding to the platelet glycoprotein Ib.Q43782195
Protease-activated receptor 4-like peptides bind to thrombin through an optimized interaction with the enzyme active site surfaceQ44078419
Domains specifying thrombin–receptor interactionQ46311150
Quantitative image analysis of F-actin in endothelial cellsQ48565128
Platelet glycoprotein Ib alpha binds to thrombin anion-binding exosite II inducing allosteric changes in the activity of thrombin.Q60265904
A stable metabolite, Arg-Pro-Pro-Gly-Phe, of bradykinin in the degradation pathway in human plasmaQ67983408
The correlation between rises in intracellular calcium and PGI2 production in cultured vascular endothelial cellsQ68023572
Bradykinin and its metabolite, Arg-Pro-Pro-Gly-Phe, are selective inhibitors of alpha-thrombin-induced platelet activationQ71401438
Solution composition dependent variation in extinction coefficients for p-nitroanilineQ71702452
The dual role of thrombin's anion-binding exosite-I in the recognition and cleavage of the protease-activated receptor 1Q73307391
Bradykinin and alpha-thrombin increase human umbilical vein endothelial macromolecular permeability by different mechanismsQ73550788
Bradykinin antagonizes the effects of alpha-thrombinQ73563380
Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in plateletsQ73811661
Site-specific thrombin receptor antibodies inhibit Ca2+ signaling and increased endothelial permeabilityQ73890603
Molecular mapping of thrombin-receptor interactionsQ74527941
TITRATION BEHAVIOR OF BOVINE THROMBINQ76848740
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)96-106
P577publication date2003-02-01
P1433published inArchives of Biochemistry and BiophysicsQ635818
P1476titleEstablishing the inhibitory effects of bradykinin on thrombin
P478volume410

Reverse relations

cites work (P2860)
Q90504580Computational design of substrate selective inhibition
Q47232006Interactions between bradykinin and plasmin in the endothelial Ca2+ response
Q27649983Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of actionin vitroandin vivo

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