The role of alpha3beta1 integrin in determining the supramolecular organization of laminin-5 in the extracellular matrix of keratinocytes

scientific article published on 01 February 2003

The role of alpha3beta1 integrin in determining the supramolecular organization of laminin-5 in the extracellular matrix of keratinocytes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-4827(02)00028-9
P698PubMed publication ID12565820

P2093author name stringKevin E Healy
Jonathan C R Jones
Gregory W deHart
P2860cites workAnchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD proteinQ24651847
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Integrin beta 4 mutations associated with junctional epidermolysis bullosa with pyloric atresiaQ28118736
A unique sequence of the laminin alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4Q28190479
Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survivalQ28592841
Traction forces mediated by alpha6beta4 integrin: implications for basement membrane organization and tumor invasionQ30856978
Structure and function of hemidesmosomes: more than simple adhesion complexesQ33592752
Biology and function of hemidesmosomesQ33657765
Dystroglycan inside and out.Q33744965
Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesionQ34026266
Laminins: structure and genetic regulationQ34071960
Calcium regulation of growth and differentiation of mouse epidermal cells in cultureQ34248695
Syndecan-4 and focal adhesion functionQ34360595
Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytesQ34730493
Expression of matrix metalloprotease-2-cleaved laminin-5 in breast remodeling stimulated by sex steroidsQ35786809
Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activatorQ36255285
Targeted disruption of the LAMA3 gene in mice reveals abnormalities in survival and late stage differentiation of epithelial cellsQ36256553
α3β1 Integrin Is Required for Normal Development of the Epidermal Basement MembraneQ36274145
Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invaginationQ36328599
Laminin polymerization induces a receptor-cytoskeleton networkQ36342173
Formation of hemidesmosomes in vitro by a transformed rat bladder cell lineQ36529093
The alpha chain of laminin-1 is independently secreted and drives secretion of its beta- and gamma-chain partners.Q36584050
The lamininsQ40574682
Studies of patients with anti-epiligrin cicatricial pemphigoidQ40943283
Long-term culture of murine epidermal keratinocytesQ40945711
Molecular complexity of the cutaneous basement membrane zone. Revelations from the paradigms of epidermolysis bullosaQ40951954
Morphogenetic effects of soluble laminin-5 on cultured epithelial cells and tissue explantsQ41155099
The alpha 6 beta 4 integrin is a receptor for both laminin and kalininQ41476163
Immunodissection of the connective tissue matrix in human skinQ41594132
The dermal-epidermal junctionQ41612536
Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranesQ41683771
Anti-basement membrane autoantibodies in patients with anti-epiligrin cicatricial pemphigoid bind the alpha subunit of laminin 5.Q42478607
Junctional epidermolysis bullosis: defects in expression of epiligrin/nicein/kalinin and integrin beta 4 that inhibit hemidesmosome formationQ42493193
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null miceQ42519143
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocystsQ42771254
Biomimetic peptide surfaces that regulate adhesion, spreading, cytoskeletal organization, and mineralization of the matrix deposited by osteoblast-like cellsQ46291259
Laminin-5 coating enhances epithelial cell attachment, spreading, and hemidesmosome assembly on Ti-6A1-4V implant material in vitroQ47924399
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.Q52200996
Dynamic aspects of the supramolecular organization of intermediate filament networks in cultured epidermal cellsQ71461438
A probabilistic approach to measure the strength of bone cell adhesion to chemically modified surfacesQ73282556
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectkeratinocyteQ1473931
P304page(s)67-79
P577publication date2003-02-01
P1433published inExperimental Cell ResearchQ1524289
P1476titleThe role of alpha3beta1 integrin in determining the supramolecular organization of laminin-5 in the extracellular matrix of keratinocytes
P478volume283

Reverse relations

cites work (P2860)
Q30478118A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence
Q37640766Adhesion and migration, the diverse functions of the laminin alpha3 subunit.
Q39852686Alpha3beta1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3.
Q39097144BPAG1-e restricts keratinocyte migration through control of adhesion stability.
Q24320148BPAG1e maintains keratinocyte polarity through beta4 integrin-mediated modulation of Rac1 and cofilin activities
Q40313892Dissociation of the complex between CD151 and laminin-binding integrins permits migration of epithelial cells
Q37858271Epithelial integrins with special reference to oral epithelia
Q39466458Fibronectin expression determines skin cell motile behavior
Q42409252Focal Contact and Hemidesmosomal Proteins in Keratinocyte Migration and Wound Repair
Q42520328Immunohistochemical profile of integrins in enlarged dental follicles and dentigerous cysts
Q42409259Integrin Regulation of Epidermal Functions in Wounds
Q37258851Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes
Q33648224Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 organization
Q28388577Integrin-mediated regulation of epidermal wound functions
Q42436561Kindlin-1 mutant zebrafish as an in vivo model system to study adhesion mechanisms in the epidermis
Q27316898Kindlin-1 regulates integrin dynamics and adhesion turnover
Q35642852Laminin 511 partners with laminin 332 to mediate directional migration of Madin-Darby canine kidney epithelial cells.
Q42693930Laminin deposition in the extracellular matrix: a complex picture emerges
Q28580749Laminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanism
Q24602789Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta
Q40604620Myosin-mediated cytoskeleton contraction and Rho GTPases regulate laminin-5 matrix assembly
Q30485268Phosphorylation of a novel site on the {beta}4 integrin at the trailing edge of migrating cells promotes hemidesmosome disassembly
Q35996553Physiological and pathological roles of alpha3beta1 integrin
Q27304390Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration
Q39612766Reduced fibulin-2 contributes to loss of basement membrane integrity and skin blistering in mice lacking integrin α3β1 in the epidermis
Q34051267Regulation of fibulin-2 gene expression by integrin α3β1 contributes to the invasive phenotype of transformed keratinocytes
Q89565608Requirement for and polarized localization of integrin proteins during Drosophila wound closure
Q51637199Respiratory epithelium in usual interstitial pneumonia/idiopathic pulmonary fibrosis: spark or destructive flame?
Q41892013The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration
Q42454185The Yin and Yang of Integrin Function in Re-Epithelialization During Wound Healing
Q38197886The integrin adhesome: from genes and proteins to human disease
Q34289595Wound healing is defective in mice lacking tetraspanin CD151

Search more.