scholarly article | Q13442814 |
P356 | DOI | 10.1002/GCC.20426 |
P698 | PubMed publication ID | 17330262 |
P2093 | author name string | Mette K Andersen | |
Debes H Christiansen | |||
Jens Pedersen-Bjergaard | |||
Frehiwet Desta | |||
P2860 | cites work | Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome | Q24291893 |
Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease | Q24540529 | ||
Occurrence of myeloproliferative disorder in patients with Noonan syndrome | Q33499657 | ||
Genetics of myeloid leukemias | Q34795893 | ||
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells | Q35847802 | ||
The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease | Q35847884 | ||
Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies | Q40308333 | ||
Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations | Q40318729 | ||
Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation | Q43824047 | ||
Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML. | Q43963802 | ||
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia | Q44419404 | ||
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis | Q44673842 | ||
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia | Q44775999 | ||
PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer Group | Q45073102 | ||
Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia | Q46799049 | ||
Cooperation of activating Ras/rtk signal transduction pathway mutations and inactivating myeloid differentiation gene mutations in M0 AML: a study of 45 patients | Q46902751 | ||
Noonan's syndrome in association with acute leukemia. | Q52012543 | ||
Acute lymphoblastic leukemia in Noonan syndrome: report of two cases | Q70772106 | ||
P433 | issue | 6 | |
P304 | page(s) | 517-521 | |
P577 | publication date | 2007-06-01 | |
P1433 | published in | Genes, Chromosomes and Cancer | Q5532697 |
P1476 | title | Mutations of the PTPN11 gene in therapy-related MDS and AML with rare balanced chromosome translocations | |
P478 | volume | 46 |
Q38226741 | -7/7q- syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity |
Q41814200 | Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia |
Q41809918 | Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation |
Q24646924 | Constitutively active SHP2 cooperates with HoxA10 overexpression to induce acute myeloid leukemia |
Q37058777 | Genetics of therapy-related myelodysplasia and acute myeloid leukemia |
Q33377270 | Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes |
Q37688148 | Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations |
Q41299821 | Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases |
Q44257677 | NPM1 mutations in therapy-related acute myeloid leukemia with uncharacteristic features |
Q44003077 | Novel oncogenic PTPN11 mutations in myelodysplastic syndrome in Korean patients |
Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
Q35825659 | Shp2 function in hematopoietic stem cell biology and leukemogenesis |
Q52870427 | Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16. |
Q37009760 | Therapy-related myeloid leukemia. |
Q38611096 | Therapy-related myeloid neoplasms: when genetics and environment collide |
Q86506687 | [Clinical and cytogenetic study of chromosome 1 abnormality in myelodysplastic syndrome] |
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