scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.YJMCC.2007.03.906 |
P698 | PubMed publication ID | 17490679 |
P2093 | author name string | Jil C Tardiff | |
Todd E Haim | |||
James Scheuer | |||
Candice Dowell | |||
Theodhor Diamanti | |||
P2860 | cites work | Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere | Q24316399 |
Calcium fluxes involved in control of cardiac myocyte contraction | Q28144050 | ||
Nebulin: the nebulous, multifunctional giant of striated muscle | Q28184022 | ||
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region | Q28199174 | ||
Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy | Q28236892 | ||
Cardiac myosin binding protein-C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy | Q28284626 | ||
Codon 102 of the cardiac troponin T gene is a putative hot spot for mutations in familial hypertrophic cardiomyopathy | Q28300903 | ||
Sudden death due to troponin T mutations | Q28305351 | ||
A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy | Q28508653 | ||
Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy | Q28588821 | ||
Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy | Q28589243 | ||
Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice | Q28593918 | ||
Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T | Q30333375 | ||
Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy | Q33144725 | ||
Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene | Q33872178 | ||
Hypertrophic cardiomyopathy: a systematic review | Q34117625 | ||
The molecular genetics of hypertrophic cardiomyopathy: prognostic implications | Q34166230 | ||
Molecular mechanisms of inherited cardiomyopathies | Q34882653 | ||
Cardiac troponin T and familial hypertrophic cardiomyopathy: an energetic affair | Q35679277 | ||
Role of troponin T in disease. | Q35938326 | ||
Nebulin regulates the assembly and lengths of the thin filaments in striated muscle | Q36320882 | ||
Sarcomeric proteins and familial hypertrophic cardiomyopathy: linking mutations in structural proteins to complex cardiovascular phenotypes | Q36369925 | ||
Cardiac-specific overexpression of phospholamban alters calcium kinetics and resultant cardiomyocyte mechanics in transgenic mice | Q37350650 | ||
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy | Q39747918 | ||
Hypertrophic cardiomyopathy. Interrelations of clinical manifestations, pathophysiology, and therapy (1). | Q39759066 | ||
A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation | Q40548710 | ||
Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy | Q40934940 | ||
Thin filament-mediated regulation of cardiac contraction | Q41117735 | ||
Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy. | Q42454138 | ||
Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling. | Q44324598 | ||
Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport | Q44590596 | ||
Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy | Q44891080 | ||
Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. | Q45091693 | ||
Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart | Q45161317 | ||
Contractile deactivation and uncoupling of crossbridges. Effects of 2,3-butanedione monoxime on mammalian myocardium | Q46233498 | ||
Mitochondrial and sarcolemmal Ca2+ transport reduce [Ca2+]i during caffeine contractures in rabbit cardiac myocytes | Q46852991 | ||
Parvalbumin corrects slowed relaxation in adult cardiac myocytes expressing hypertrophic cardiomyopathy-linked alpha-tropomyosin mutations | Q47834435 | ||
Early changes in excitation-contraction coupling: transition from compensated hypertrophy to failure in Dahl salt-sensitive rat myocytes. | Q54135977 | ||
A De Novo Mutation in α-Tropomyosin That Causes Hypertrophic Cardiomyopathy | Q57279253 | ||
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1 | Q64378890 | ||
Contractile reserve and intracellular calcium regulation in mouse myocytes from normal and hypertrophied failing hearts | Q73015376 | ||
Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy | Q73019334 | ||
Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice | Q74619276 | ||
Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction | Q75256454 | ||
Folding and function of the troponin tail domain. Effects of cardiomyopathic troponin T mutations | Q78454995 | ||
P433 | issue | 6 | |
P304 | page(s) | 1098-1110 | |
P577 | publication date | 2007-03-31 | |
P1433 | published in | Journal of Molecular and Cellular Cardiology | Q2061932 |
P1476 | title | Independent FHC-related cardiac troponin T mutations exhibit specific alterations in myocellular contractility and calcium kinetics | |
P478 | volume | 42 |
Q30660058 | A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function |
Q37504006 | A clinical approach to inherited hypertrophy: the use of family history in diagnosis, risk assessment, and management. |
Q34600346 | Abnormal heart rate regulation in murine hearts with familial hypertrophic cardiomyopathy-related cardiac troponin T mutations |
Q50194792 | Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy. |
Q36600756 | Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy |
Q58699044 | Altered Ca and Na Homeostasis in Human Hypertrophic Cardiomyopathy: Implications for Arrhythmogenesis |
Q34470455 | Cardiac myosin heavy chain isoform exchange alters the phenotype of cTnT-related cardiomyopathies in mouse hearts |
Q38724869 | Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility |
Q27010320 | Cell biology of sarcomeric protein engineering: disease modeling and therapeutic potential |
Q37413071 | Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies. |
Q33997765 | Experimental therapies in hypertrophic cardiomyopathy |
Q37284441 | HCM-linked ∆160E cardiac troponin T mutation causes unique progressive structural and molecular ventricular remodeling in transgenic mice |
Q37855688 | How do mutations in contractile proteins cause the primary familial cardiomyopathies? |
Q54979120 | Hypertrophic cardiomyopathy mutations increase myofilament Ca2+ buffering, alter intracellular Ca2+ handling and stimulate Ca2+ dependent signalling. |
Q33992358 | Hypertrophic cardiomyopathy: from genetics to treatment |
Q34995673 | Independent modulation of contractile performance by cardiac troponin I Ser43 and Ser45 in the dynamic sarcomere. |
Q28242903 | Long term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy |
Q36923785 | Mechanical and energetic properties of papillary muscle from ACTC E99K transgenic mouse models of hypertrophic cardiomyopathy |
Q36534070 | Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT. |
Q47705176 | Molecular mechanisms and structural features of cardiomyopathy-causing troponin T mutants in the tropomyosin overlap region |
Q34474908 | Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy |
Q35880670 | Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy. |
Q41627235 | Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models. |
Q28265173 | Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro |
Q50864373 | Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy. |
Q27027023 | Targets for therapy in sarcomeric cardiomyopathies |
Q30489417 | Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models |
Q50951425 | The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy. |
Q28307606 | Thin filament mutations: developing an integrative approach to a complex disorder |
Q26996693 | Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor |
Search more.