| Q90322079 | A Mouse Noninvasive Intraarticular Tibial Plateau Compression Loading-Induced Injury Model of Posttraumatic Osteoarthritis |
| Q30432076 | A commentary on modelling osteoarthritis pain in small animals |
| Q36165445 | A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis |
| Q36246878 | A novel method to detect articular chondrocyte death during early stages of osteoarthritis using a non-invasive ApoPep-1 probe. |
| Q91792141 | Aberrant expression of Twist1 in diseased articular cartilage and a potential role in the modulation of osteoarthritis severity |
| Q33765726 | Accelerated and increased joint damage in young mice with global inactivation of mitogen-inducible gene 6 after ligament and meniscus injury. |
| Q36028164 | Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage |
| Q41785351 | Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee |
| Q37633355 | Age-dependent Changes in the Articular Cartilage and Subchondral Bone of C57BL/6 Mice after Surgical Destabilization of Medial Meniscus. |
| Q91045716 | Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5 |
| Q47429470 | An Alternative Method to Characterize the Quasi-Static, Nonlinear Material Properties of Murine Articular Cartilage. |
| Q35201115 | Analysis of osteoarthritis in a mouse model of the progeroid human DNA repair syndrome trichothiodystrophy. |
| Q37281085 | Animal models of osteoarthritis for the understanding of the bone contribution |
| Q40813657 | Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg. |
| Q35803625 | Autophagy activation by rapamycin reduces severity of experimental osteoarthritis. |
| Q30401142 | Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1 |
| Q34225355 | Biological aspects of early osteoarthritis |
| Q48121391 | Biomechanical factors influencing the beginning and development of osteoarthritis in the hip joint |
| Q41884966 | Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes |
| Q36245833 | Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes |
| Q33410797 | C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57. |
| Q52604134 | CCL17 blockade as a therapy for osteoarthritis pain and disease. |
| Q37291220 | CD8+ T cell-induced expression of tissue inhibitor of metalloproteinses-1 exacerbated osteoarthritis |
| Q57949139 | Carminerin contributes to chondrocyte calcification during endochondral ossification |
| Q92422137 | Cartilage and Bone Destruction in Arthritis: Pathogenesis and Treatment Strategy: A Literature Review |
| Q35847568 | Cartilage matrix changes in contralateral mobile knees in a rabbit model of osteoarthritis induced by immobilization |
| Q35765280 | Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture |
| Q33839599 | Characterization of human osteoarthritic cartilage using optical and magnetic resonance imaging. |
| Q89948931 | Chondro-protective effects of celastrol on osteoarthritis through autophagy activation and NF-κB signaling pathway inhibition |
| Q33987148 | Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal p |
| Q64279261 | Chondroprotection of PPARα activation by WY14643 via autophagy involving Akt and ERK in LPS-treated mouse chondrocytes and osteoarthritis model |
| Q35644533 | Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis. |
| Q38732097 | Controlling Abnormal Joint Movement Inhibits Response of Osteophyte Formation. |
| Q36035121 | Coordinate and synergistic effects of extensive treadmill exercise and ovariectomy on articular cartilage degeneration |
| Q98238617 | Cordycepin Alleviates Anterior Cruciate Ligament Transection (ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity and Autophagy |
| Q55209348 | Cyclic compressive loading activates angiotensin II type 1 receptor in articular chondrocytes and stimulates hypertrophic differentiation through a G-protein-dependent pathway. |
| Q41881337 | DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. |
| Q33843130 | Decrease in the expression of the type 1 PTH/PTHrP receptor (PTH1R) on chondrocytes in animals with osteoarthritis |
| Q34695447 | Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of hum |
| Q37071562 | Deficiency of G-protein coupled receptor 40, a lipid-activated receptor, heightens in vitro- and in vivo-induced murine osteoarthritis |
| Q37676291 | Depletion of Gangliosides Enhances Articular Cartilage Repair in Mice. |
| Q64056943 | Discerning the spatio-temporal disease patterns of surgically induced OA mouse models |
| Q37689672 | Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice |
| Q90167820 | Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis |
| Q43123292 | Early response of mouse joint tissue to noninvasive knee injury suggests treatment targets |
| Q92740308 | Early-Onset Osteoarthritis originates at the chondrocyte level in Hip Dysplasia |
| Q64889934 | Effects of Controlling Abnormal Joint Movement on Expression of MMP13 and TIMP-1 in Osteoarthritis. |
| Q35681213 | Effects of diacerein on cartilage and subchondral bone in early stages of osteoarthritis in a rabbit model |
| Q42046724 | Establishment of an index with increased sensitivity for assessing murine arthritis. |
| Q64104251 | Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway |
| Q35769088 | Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis |
| Q34182597 | Gene expression analyses of subchondral bone in early experimental osteoarthritis by microarray |
| Q28384478 | Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping |
| Q55472630 | Guava leaf extract suppresses osteoarthritis progression in a rat anterior cruciate ligament transection model. |
| Q35907775 | High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury |
| Q96640540 | Histological scoring system for subchondral bone changes in murine models of joint aging and osteoarthritis |
| Q41508057 | How different methodologies of harvesting and analysing the samples affect the test results in determining joint mediators |
| Q90665169 | Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling |
| Q34784793 | Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis |
| Q34230334 | Identification of a central role for complement in osteoarthritis |
| Q64055942 | IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis |
| Q36901931 | In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae |
| Q37690510 | Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage |
| Q28387881 | Increased serum and musculotendinous fibrogenic proteins following persistent low-grade inflammation in a rat model of long-term upper extremity overuse |
| Q36242292 | Inflammation in joint injury and post-traumatic osteoarthritis |
| Q30540454 | Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis |
| Q34673887 | Initial responses of articular tissues in a murine high-fat diet-induced osteoarthritis model: pivotal role of the IPFP as a cytokine fountain |
| Q59812517 | Intra-Articular Injection of Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats |
| Q51124753 | Intra-articular Injection of Urinary Bladder Matrix Reduces Osteoarthritis Development. |
| Q58602485 | Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis |
| Q42534501 | Joint instability and cartilage compression in a mouse model of posttraumatic osteoarthritis |
| Q49823517 | Kinematics of meniscal- and ACL-transected mouse knees during controlled tibial compressive loading captured using roentgen stereophotogrammetry |
| Q35030282 | Knee loading reduces MMP13 activity in the mouse cartilage |
| Q99551245 | Knee osteoarthritis in young growing rats is associated with widespread osteopenia and impaired bone mineralization |
| Q37208260 | Lentiviral small hairpin RNA knockdown of macrophage inflammatory protein-1γ ameliorates experimentally induced osteoarthritis in mice |
| Q81217971 | Lessons from animal models of osteoarthritis |
| Q50099362 | Loading-Induced Reduction in Sclerostin as a Mechanism of Subchondral Bone Plate Sclerosis in Mouse Knee Joints During Late-Stage Osteoarthritis |
| Q41852286 | Long-term histopathological developments in knee-joint components in a rat model of osteoarthritis induced by monosodium iodoacetate |
| Q42534822 | Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors |
| Q33706862 | Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. |
| Q36428199 | Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment |
| Q47096377 | MicroRNA-145 attenuates TNF-α-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4. |
| Q58561726 | Models of osteoarthritis: the good, the bad and the promising |
| Q35222605 | Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis |
| Q39307549 | Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB. |
| Q38198901 | Mouse models of osteoarthritis: modelling risk factors and assessing outcomes. |
| Q34783518 | Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology--a systematic review |
| Q40718621 | NELL-1 promotes cartilage regeneration in an in vivo rabbit model |
| Q37377454 | NFATc1 and NFATc2 repress spontaneous osteoarthritis |
| Q90145216 | Naturally occurring osteoarthritis in male mice with an extended lifespan |
| Q47104080 | New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis |
| Q28546348 | Non-Invasive Quantification of Cartilage Using a Novel In Vivo Bioluminescent Reporter Mouse |
| Q36079841 | Non-invasive mouse models of post-traumatic osteoarthritis |
| Q36583027 | Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development |
| Q59942491 | Novel model for the induction of postnatal murine hip deformity |
| Q26781301 | On the predictive utility of animal models of osteoarthritis |
| Q85209342 | Optimization of matrix metalloproteinase fluorogenic probes for osteoarthritis imaging |
| Q30362361 | Oral Administration of Resveratrol Alleviates Osteoarthritis Pathology in C57BL/6J Mice Model Induced by a High-Fat Diet |
| Q30384235 | Oral Resveratrol Prevents Osteoarthritis Progression in C57BL/6J Mice Fed a High-Fat Diet |
| Q92335638 | Oral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion |
| Q37588803 | Osteoarthritis: toward a comprehensive understanding of pathological mechanism |
| Q91176921 | Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis |
| Q36128347 | Pleiotropic Functions of High Fat Diet in the Etiology of Osteoarthritis |
| Q37721704 | Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial Joint |
| Q42316518 | Progressive cell-mediated changes in articular cartilage and bone in mice are initiated by a single session of controlled cyclic compressive loading |
| Q55655714 | Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGFβ-dependent manner and limits osteoarthritis in mice. |
| Q37681252 | Protective effects of calcium gluconate on osteoarthritis induced by anterior cruciate ligament transection and partial medial meniscectomy in Sprague-Dawley rats |
| Q36765161 | Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
| Q49799067 | Quantitative Morphometry for Osteochondral Tissues Using Second Harmonic Generation Microscopy and Image Texture Information |
| Q41770221 | Quantitative SHG imaging in osteoarthritis model mice, implying a diagnostic application |
| Q91899291 | REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis |
| Q36591441 | Response of knee fibrocartilage to joint destabilization |
| Q35198953 | Role of osteal macrophages in bone metabolism |
| Q64273617 | Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation |
| Q38818198 | SGTB Promotes the Caspase-Dependent Apoptosis in Chondrocytes of Osteoarthritis |
| Q34565410 | SOX11 contributes to the regulation of GDF5 in joint maintenance |
| Q38836896 | Sam68 Promotes NF-κB Activation and Apoptosis Signaling in Articular Chondrocytes during Osteoarthritis |
| Q24312767 | Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: identification of sorting nexin 19 as a novel factor |
| Q28552506 | Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis |
| Q52914363 | Stress-Induced Activation of Apoptosis Signal-Regulating Kinase 1 Promotes Osteoarthritis. |
| Q34997730 | Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis |
| Q37349431 | Synovial perlecan is required for osteophyte formation in knee osteoarthritis |
| Q37146817 | Systemic neutralization of TGF-β attenuates osteoarthritis |
| Q37745409 | TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis |
| Q35217084 | Targeted mutation of NOV/CCN3 in mice disrupts joint homeostasis and causes osteoarthritis-like disease |
| Q35525309 | Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. |
| Q55002167 | Tetrahydrohyperforin prevents articular cartilage degeneration and affects autophagy in rats with osteoarthritis. |
| Q33728287 | The amelioration of cartilage degeneration by photo-crosslinked GelHA hydrogel and crizotinib encapsulated chitosan microspheres |
| Q90404022 | The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway against experimental osteoarthritis |
| Q43120812 | The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease |
| Q36345941 | Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading |
| Q85523794 | Total dislocation of the hip joint after arthroscopy and ileopsoas tenotomy |
| Q35190041 | Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2. |
| Q51907850 | Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. |
| Q34266000 | Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation |
| Q97067308 | Understanding cartilage protection in OA and injury: a spectrum of possibilities |
| Q38090972 | Useful animal models for the research of osteoarthritis |
| Q48027015 | Vacuolar Protein Sorting 4B (VPS4B) Regulates Apoptosis of Chondrocytes via p38 Mitogen-Activated Protein Kinases (MAPK) in Osteoarthritis |
| Q35128175 | Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling |
| Q64936611 | Wwp2 maintains cartilage homeostasis through regulation of Adamts5. |
| Q61813443 | miR-10a-5p Promotes Chondrocyte Apoptosis in Osteoarthritis by Targeting HOXA1 |
| Q33815871 | miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2 |