| scholarly article | Q13442814 |
| review article | Q7318358 |
| P6179 | Dimensions Publication ID | 1092617686 |
| P356 | DOI | 10.1186/S13075-017-1454-2 |
| P932 | PMC publication ID | 5681770 |
| P698 | PubMed publication ID | 29126436 |
| P2093 | author name string | Heng Li | |
| Dan Wang | |||
| Yongjian Yuan | |||
| Jikang Min | |||
| P2860 | cites work | Biochemical characterization of human collagenase-3 | Q24318765 |
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| miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice | Q24595073 | ||
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| Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks | Q28474080 | ||
| Diagnosis and Clinical Presentation of Osteoarthritis | Q60704760 | ||
| Osteoarthritis development in novel experimental mouse models induced by knee joint instability | Q81752148 | ||
| Autophagy modulates osteoarthritis-related gene expression in human chondrocytes | Q82837043 | ||
| Hylan G-F 20 maintains cartilage integrity and decreases osteophyte formation in osteoarthritis through both anabolic and anti-catabolic mechanisms | Q84585876 | ||
| A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis | Q85265446 | ||
| MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes | Q85718298 | ||
| Diabetes-accelerated experimental osteoarthritis is prevented by autophagy activation | Q87845924 | ||
| MicroRNA-181b regulates articular chondrocytes differentiation and cartilage integrity. | Q50765296 | ||
| Early cartilage degeneration in a rat experimental model of developmental dysplasia of the hip. | Q50803309 | ||
| The expression of intronic miRNAs, miR-483 and miR-483*, and their host gene, Igf2, in murine osteoarthritis cartilage. | Q50886863 | ||
| Analysis of cartilage biomarkers in the early phases of canine experimental osteoarthritis. | Q51051011 | ||
| Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis. | Q51358717 | ||
| Transcriptional regulation of MMP13 by Lef1 in chondrocytes. | Q51577326 | ||
| Applying an excessive mechanical stress alters the effect of subchondral osteoblasts on chondrocytes in a co-culture system. | Q51908042 | ||
| MicroRNA-320 regulates matrix metalloproteinase-13 expression in chondrogenesis and interleukin-1β-induced chondrocyte responses. | Q53207366 | ||
| The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13. | Q53524092 | ||
| Long noncoding RNA related to cartilage injury promotes chondrocyte extracellular matrix degradation in osteoarthritis. | Q54211983 | ||
| Insulin decreases autophagy and leads to cartilage degradation. | Q54235231 | ||
| Changes in microRNA expression in peripheral mononuclear cells according to the progression of osteoarthritis. | Q54343577 | ||
| Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells | Q54400886 | ||
| Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage. | Q54615798 | ||
| Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions. | Q54638931 | ||
| Interleukin-4 downregulates the cyclic tensile stress-induced matrix metalloproteinases-13 and cathepsin B expression by rat normal chondrocytes | Q28584131 | ||
| Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes | Q30931885 | ||
| Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. | Q33706862 | ||
| Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis | Q33729300 | ||
| p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis. | Q33766656 | ||
| Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis | Q34115101 | ||
| Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145) | Q34234586 | ||
| Celecoxib: a review of its use for symptomatic relief in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis | Q34238267 | ||
| Osteoarthritis: diagnosis and treatment. | Q34245808 | ||
| Impact of osteoarthritis on individuals and society: how much disability? Social consequences and health economic implications | Q34793650 | ||
| MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis | Q34984847 | ||
| Characterization of the cartilage DNA methylome in knee and hip osteoarthritis | Q35040983 | ||
| MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. | Q35114604 | ||
| MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes | Q35222459 | ||
| Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis | Q35222605 | ||
| Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis | Q35764680 | ||
| The protective role of autophagy in experimental osteoarthritis, and the therapeutic effects of Torin 1 on osteoarthritis by activating autophagy | Q35981646 | ||
| Considerations in the treatment of early osteoarthritis | Q36067679 | ||
| Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention | Q36171836 | ||
| MicroRNA-125b down-regulates matrix metallopeptidase 13 and inhibits cutaneous squamous cell carcinoma cell proliferation, migration, and invasion | Q36215845 | ||
| MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis | Q36323810 | ||
| Integrins and chondrocyte-matrix interactions in articular cartilage | Q36425948 | ||
| DNA methylation in osteoarthritic chondrocytes: a new molecular target | Q36565318 | ||
| Circular RNA Related to the Chondrocyte ECM Regulates MMP13 Expression by Functioning as a MiR-136 'Sponge' in Human Cartilage Degradation | Q36638569 | ||
| Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis. | Q36681782 | ||
| Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites | Q36742102 | ||
| Downregulation of the long non-coding RNA TUSC7 promotes NSCLC cell proliferation and correlates with poor prognosis | Q36841220 | ||
| MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis | Q36996533 | ||
| Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens | Q37055039 | ||
| Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair? | Q37078072 | ||
| The colorful history of active DNA demethylation. | Q37201774 | ||
| Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage | Q37365557 | ||
| MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1 | Q37488265 | ||
| Role of microRNA-mediated MMP regulation in the treatment and diagnosis of malignant tumors | Q37540188 | ||
| Physiological functions of autophagy | Q37608026 | ||
| Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. | Q37609032 | ||
| Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells. | Q37653289 | ||
| Osteoarthritis: an update with relevance for clinical practice | Q37891476 | ||
| Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs. | Q37979063 | ||
| DNA methylation dynamics in health and disease | Q38086773 | ||
| Function and information content of DNA methylation | Q38319920 | ||
| cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. | Q38326101 | ||
| AU-rich elements in the collagenase 3 mRNA mediate stabilization of the transcript by cortisol in osteoblasts | Q38347551 | ||
| Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage. | Q38406442 | ||
| DNA methylation profiling in different phases of temporomandibular joint osteoarthritis in rats | Q38448004 | ||
| Epigenetic differences in human cartilage between mild and severe OA. | Q38472690 | ||
| Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage | Q38475385 | ||
| Noncoding RNAs, cytokines, and inflammation-related diseases | Q38525235 | ||
| Autophagy in osteoarthritis | Q38603339 | ||
| MicroRNAs: exploring new horizons in osteoarthritis | Q38635765 | ||
| Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis | Q38681743 | ||
| Genome-wide profiling of long non-coding RNA expression patterns in the EGFR-TKI resistance of lung adenocarcinoma by microarray | Q38775829 | ||
| DNA methylation and hypertension: emerging evidence and challenges. | Q38824522 | ||
| LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes | Q39227561 | ||
| C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes | Q39440982 | ||
| Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs | Q39874097 | ||
| DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes | Q41352907 | ||
| Role of HTRA1, a serine protease, in the progression of articular cartilage degeneration | Q41577617 | ||
| Early-onset osteoarthritis of mouse temporomandibular joint induced by partial discectomy | Q41860022 | ||
| Intra-articular injection of Torin 1 reduces degeneration of articular cartilage in a rabbit osteoarthritis model | Q42273139 | ||
| A novel compressive stress-based osteoarthritis-like chondrocyte system | Q42587060 | ||
| Histone deacetylase inhibitors suppress mechanical stress-induced expression of RUNX-2 and ADAMTS-5 through the inhibition of the MAPK signaling pathway in cultured human chondrocytes | Q43526352 | ||
| Inhibition of interleukin-1beta-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage | Q44762076 | ||
| Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients | Q45750089 | ||
| Enhancement of chondrocyte autophagy is an early response in the degenerative cartilage of the temporomandibular joint to biomechanical dental stimulation | Q45758742 | ||
| Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes | Q45826317 | ||
| Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway | Q46485316 | ||
| High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis. | Q47331875 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | peptide | Q172847 |
| enzyme | Q8047 | ||
| human musculoskeletal system | Q726543 | ||
| gene regulatory network | Q1502576 | ||
| osteoarthritis | Q62736 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 248 | |
| P577 | publication date | 2017-11-10 | |
| P1433 | published in | Arthritis Research and Therapy | Q15757229 |
| P1476 | title | New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis | |
| P478 | volume | 19 |
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