Liraglutide suppresses TNF-α-induced degradation of extracellular matrix in human chondrocytes: a therapeutic implication in osteoarthritis

scientific article published on 15 August 2019

Liraglutide suppresses TNF-α-induced degradation of extracellular matrix in human chondrocytes: a therapeutic implication in osteoarthritis is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID6731440
P698PubMed publication ID31497200

P2093author name stringJin Wu
Jie Sun
Jing Mei
Xiannian Zheng
P2860cites workGLP-1 receptor agonists: a review of head-to-head clinical studiesQ26823768
Glucagon-like peptide-1 receptor agonist Liraglutide has anabolic bone effects in ovariectomized rats without diabetesQ28546539
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ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritisQ34205901
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.Q34607880
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Age and obesity are risk factors for adverse events after total hip arthroplastyQ35663369
Aggrecan heterogeneity in articular cartilage from patients with osteoarthritisQ35927701
Circulation and degradation of GIP and GLP-1.Q36012469
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The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritisQ36292749
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The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism.Q37139985
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Efficacy and safety of liraglutide 3.0 mg for weight management are similar across races: subgroup analysis across the SCALE and phase II randomized trialsQ40130466
Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis.Q42486191
Harpagoside suppresses IL-6 expression in primary human osteoarthritis chondrocytesQ46563144
New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritisQ47104080
Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat.Q50055684
Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes.Q51785699
Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral DensityQ61808072
Reactive oxygen species and NADPH oxidase 4 involvement in osteoarthritisQ90250453
A comparative study of the binding properties, dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucose-lowering efficacy of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in miceQ91991783
NF-κB Signaling Pathways in Osteoarthritic Cartilage DestructionQ91994891
P433issue8
P921main subjectosteoarthritisQ62736
P304page(s)4800-4808
P577publication date2019-08-15
P1433published inAmerican Journal of Translational ResearchQ4744272
P1476titleLiraglutide suppresses TNF-α-induced degradation of extracellular matrix in human chondrocytes: a therapeutic implication in osteoarthritis
P478volume11

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