| scholarly article | Q13442814 |
| P2093 | author name string | Lin Xu | |
| Peter L Lee | |||
| Yefu Li | |||
| Ilona Polur | |||
| Doil Kim | |||
| Kimberly Chung | |||
| Jacqueline Servais | |||
| P2860 | cites work | Peptides of type II collagen can induce the cleavage of type II collagen and aggrecan in articular cartilage | Q57086095 |
| Premature osteoarthritis in the Disproportionate micromelia (Dmm) mouse | Q61713522 | ||
| Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho) | Q73401298 | ||
| Effect of collagen turnover on the accumulation of advanced glycation end products | Q74281392 | ||
| Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen | Q80201579 | ||
| Abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice | Q80335899 | ||
| Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis | Q80707124 | ||
| Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice | Q80918755 | ||
| Increased expression of discoidin domain receptor 2 is linked to the degree of cartilage damage in human knee joints: a potential role in osteoarthritis pathogenesis | Q81517435 | ||
| A critical role for collagen II in cartilage matrix degradation: collagen II induces pro-inflammatory cytokines and MMPs in primary human chondrocytes | Q81699124 | ||
| Mice deficient in biglycan and fibromodulin as a model for temporomandibular joint osteoarthritis | Q83150420 | ||
| Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage | Q22008533 | ||
| The discoidin domain receptor tyrosine kinases are activated by collagen | Q24313329 | ||
| Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage | Q24562729 | ||
| Spondylo-epi-metaphyseal dysplasia (SEMD) matrilin 3 type: homozygote matrilin 3 mutation in a novel form of SEMD | Q24675483 | ||
| An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors | Q28276070 | ||
| The role of human HtrA1 in arthritic disease | Q28288792 | ||
| The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2 | Q28293395 | ||
| Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia | Q28297153 | ||
| The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism | Q28365928 | ||
| Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease | Q28509200 | ||
| Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. | Q33706862 | ||
| Update on the biology of the chondrocyte and new approaches to treating cartilage diseases | Q36596176 | ||
| A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse | Q36826539 | ||
| Developmental and osteoarthritic changes in Col6a1-knockout mice: biomechanics of type VI collagen in the cartilage pericellular matrix. | Q37299986 | ||
| The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis | Q37354475 | ||
| Altered endochondral bone development in matrix metalloproteinase 13-deficient mice | Q37407318 | ||
| OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed? | Q37475275 | ||
| Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis | Q38515107 | ||
| The biology of osteoarthritis | Q38627467 | ||
| Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice | Q39904130 | ||
| Ultrastructure of adult human articular cartilage matrix after cryotechnical processing | Q41499360 | ||
| Role of HTRA1, a serine protease, in the progression of articular cartilage degeneration | Q41577617 | ||
| Articular cartilage chondrons: form, function and failure | Q41582715 | ||
| Chondrons from articular cartilage. III. Morphologic changes in the cellular microenvironment of chondrons isolated from osteoarthritic cartilage | Q41768283 | ||
| Early-onset osteoarthritis of mouse temporomandibular joint induced by partial discectomy | Q41860022 | ||
| Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis | Q46579960 | ||
| Characterization of high affinity binding motifs for the discoidin domain receptor DDR2 in collagen | Q46803462 | ||
| Chondrons from articular cartilage (II): Analysis of the glycosaminoglycans in the cellular microenvironment of isolated canine chondrons. | Q54332955 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | osteoarthritis | Q62736 |
| P304 | page(s) | 2736-44 | |
| P577 | publication date | 2010-09-01 | |
| P1433 | published in | Arthritis & Rheumatology | Q4797636 |
| P1476 | title | Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice | |
| P478 | volume | 62 |
| Q47833499 | A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis |
| Q26740406 | A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology |
| Q37633355 | Age-dependent Changes in the Articular Cartilage and Subchondral Bone of C57BL/6 Mice after Surgical Destabilization of Medial Meniscus. |
| Q35809804 | Articular cartilage degradation in osteoarthritis |
| Q36240634 | Attenuation of the progression of articular cartilage degeneration by inhibition of TGF-β1 signaling in a mouse model of osteoarthritis |
| Q34225355 | Biological aspects of early osteoarthritis |
| Q45962394 | CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis. |
| Q37938702 | Cartilage biology in osteoarthritis--lessons from developmental biology |
| Q60305246 | Cell-Matrix Interactions and Matricrine Signaling in the Pathogenesis of Vascular Calcification |
| Q36111296 | Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis |
| Q36242603 | Deficiency of hyaluronan synthase 1 (Has1) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage. |
| Q33606304 | Delayed progression of condylar cartilage degeneration, by reduction of the discoidin domain receptor 2, in the temporomandibular joints of osteoarthritic mouse models |
| Q92558069 | Deletion of discoidin domain receptor 2 attenuates renal interstitial fibrosis in a murine unilateral ureteral obstruction model |
| Q38974944 | Differences in type II collagen turnover of osteoarthritic human knee and ankle joints. |
| Q34296706 | Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse |
| Q35043116 | Discoidin domain receptor 2 is a critical regulator of epithelial-mesenchymal transition. |
| Q33611605 | Discoidin domain receptor functions in physiological and pathological conditions |
| Q33605357 | Discoidin domain receptors in disease |
| Q88405318 | Discoidin domain receptors: Microenvironment sensors that promote cellular migration and invasion |
| Q37354205 | Discoipyrroles A-D: isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis |
| Q51154552 | Early, focal changes in cartilage cellularity and structure following surgically induced meniscal destabilization in the mouse. |
| Q92740308 | Early-Onset Osteoarthritis originates at the chondrocyte level in Hip Dysplasia |
| Q35764680 | Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis |
| Q35854320 | Evaluation of correlation of articular cartilage staining for DDR2 and proteoglycans with histological tissue damage and the results of radiographic assessment in patients with early stages of knee osteoarthritis |
| Q36948397 | Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice |
| Q26822238 | Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets |
| Q42245886 | Histopathology of naturally occurring and surgically induced osteoarthritis in mice |
| Q40890795 | Human adipose-derived mesenchymal progenitor cells engraft into rabbit articular cartilage |
| Q41841252 | Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling |
| Q54494658 | In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis. |
| Q39591802 | Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis |
| Q37608903 | Inflammation in osteoarthritis |
| Q36878348 | Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE) |
| Q28079781 | Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis |
| Q35167937 | Intact pericellular matrix of articular cartilage is required for unactivated discoidin domain receptor 2 in the mouse model |
| Q102210982 | LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilage |
| Q40490102 | Loss of discoidin domain receptor 2 promotes hepatic fibrosis after chronic carbon tetrachloride through altered paracrine interactions between hepatic stellate cells and liver-associated macrophages. |
| Q37004050 | Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology. |
| Q90383332 | Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice |
| Q37994660 | Mapping pathogenesis of arthritis through small animal models |
| Q46623248 | Molecular basis and functional significance of Angiotensin II-induced increase in Discoidin Domain Receptor 2 gene expression in cardiac fibroblasts. |
| Q36515489 | New findings in osteoarthritis pathogenesis: therapeutic implications. |
| Q47104080 | New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis |
| Q55512084 | Osteoarthritis-Like Changes in Bardet-Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation. |
| Q99545920 | Osteoarthritis: Prognosis and emerging therapeutic approach for disease management |
| Q34258870 | Osteoarthritis: a disease of the joint as an organ |
| Q35586231 | Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention |
| Q28293851 | Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants |
| Q38108123 | Post-traumatic osteoarthritis: from mouse models to clinical trials |
| Q35560686 | Proteases involved in cartilage matrix degradation in osteoarthritis. |
| Q37609032 | Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. |
| Q46308661 | Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging |
| Q34933824 | Structural variations in articular cartilage matrix are associated with early-onset osteoarthritis in the spondyloepiphyseal dysplasia congenita (sedc) mouse |
| Q40716006 | Tackling chondrocyte hypertrophy with multifunctional nanoparticles. |
| Q41653958 | Targeting of Discoidin Domain Receptor 2 (DDR2) Prevents Myofibroblast Activation and Neovessel Formation During Pulmonary Fibrosis |
| Q35376231 | The anti-angiogenic role of discoidin domain receptor 2 (DDR2) in laser-induced choroidal neovascularization |
| Q90054832 | Topical Application of Wogonin Provides a Novel Treatment of Knee Osteoarthritis |
| Q64067271 | Two-photon fluorescence and second harmonic generation characterization of extracellular matrix remodeling in post-injury murine temporomandibular joint osteoarthritis |
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