HOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocation

scientific article published on 01 June 2006

HOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocation is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1046954353
P356DOI10.1038/SJ.LEU.2404187
P698PubMed publication ID16572206

P50authorEric DelabesseQ57287418
P2093author name stringSoulier J
Speleman F
Bergeron J
Beldjord K
Dastugue N
Macintyre E
Asnafi V
Millien C
Cauwelier B
Clappier E
P2860cites workA new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemiasQ28304589
MLL targets SET domain methyltransferase activity to Hox gene promotersQ28609771
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemiaQ38294261
V(D)J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites.Q39017691
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).Q52054808
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes.Q54648219
Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy.Q54723450
CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCRgammadelta lineage.Q54780165
P433issue6
P304page(s)1184-1187
P577publication date2006-06-01
P1433published inLeukemiaQ6534498
P1476titleHOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocation
P478volume20

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cites work (P2860)
Q38125650Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia
Q47293487Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRbeta-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique.
Q33587655Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults
Q37783244Control of Vertebrate Hox Clusters by Remote and Global Cis-Acting Regulatory Sequences
Q81740968Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia
Q24682728Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice
Q24624017Gene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223
Q42397478HOXA-activated early T-cell progenitor acute lymphoblastic leukemia: predictor of poor outcome?
Q54567088High incidence of CALM-AF10 fusion and the identification of a novel fusion transcript in acute megakaryoblastic leukemia in children without Down's syndrome.
Q34700749Hox genes in hematopoiesis and leukemogenesis.
Q33558120Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.
Q33788690Inactivation of LEF1 in T-cell acute lymphoblastic leukemia
Q91714241RAS and TP53 can predict survival in adults with T-cell lymphoblastic leukemia treated with hyper-CVAD

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