Control of Vertebrate Hox Clusters by Remote and Global Cis-Acting Regulatory Sequences

scientific article published on January 1, 2010

Control of Vertebrate Hox Clusters by Remote and Global Cis-Acting Regulatory Sequences is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/978-1-4419-6673-5_4
P953full work available at URLhttps://link.springer.com/content/pdf/10.1007/978-1-4419-6673-5_4
P698PubMed publication ID20795322

P50authorFrançois SpitzQ59662672
P2860cites workHox genes and the making of sphinctersQ73148523
Control of Hoxd genes' collinearity during early limb developmentQ82202978
HOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocationQ83007216
Analysis of Hox gene expression in the chick limb budQ112778197
A global control region defines a chromosomal regulatory landscape containing the HoxD clusterQ24301317
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcriptionQ24563638
Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of DrosophilaQ24595240
Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbnessQ24644773
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Hox10 and Hox11 genes are required to globally pattern the mammalian skeletonQ28188034
ChIP-seq accurately predicts tissue-specific activity of enhancersQ28235102
Hox patterning of the vertebrate rib cageQ28508110
Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1Q28593607
MicroRNAs in the Hox network: an apparent link to posterior prevalenceQ28752243
Biphasic Hoxd gene expression in shark paired fins reveals an ancient origin of the distal limb domainQ28757269
A gene complex controlling segmentation in DrosophilaQ29547506
Hox genes in vertebrate developmentQ29618109
Evx2-Hoxd13 intergenic region restricts enhancer association to Hoxd13 promoterQ33270098
Why are Hox genes clustered?Q33368212
Hox genes in digit development and evolutionQ33592049
Selectivity, sharing and competitive interactions in the regulation of Hoxb genesQ33888526
Ancestral and recently recruited global control of the Hox genes in developmentQ34006982
Organizing axes in time and space; 25 years of colinear tinkeringQ34215299
A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexesQ34255549
Genomic evolution of Hox gene clustersQ34569836
Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clustersQ34598442
The rise and fall of Hox gene clustersQ34635194
Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant miceQ34865785
Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovationsQ35081021
The expression of murine Hox-2 genes id dependent on the differenation pathway and displays a collinear sensitivity to retinoic acid in F9 cels andXenopusembroysQ35787628
Ectopic nuclear reorganisation driven by a Hoxb1 transgene transposed into HoxdQ36482575
Analysis of the Tribolium homeotic complex: insights into mechanisms constraining insect Hox clustersQ36538535
Breakpoints around the HOXD cluster result in various limb malformations.Q36930275
Beta-globin regulation and long-range interactionsQ37087577
Ciona intestinalis Hox gene cluster: Its dispersed structure and residual colinear expression in developmentQ37589522
Hox and HOM: homologous gene clusters in insects and vertebratesQ38348792
Hox cluster polarity in early transcriptional availability: a high order regulatory level of clustered Hox genes in the mouseQ39401987
Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrainQ39696674
Colinearity and functional hierarchy among genes of the homeotic complexesQ40646505
Organization of human homeobox genesQ41347691
Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cellsQ41724610
Ancient duplicated conserved noncoding elements in vertebrates: a genomic and functional analysisQ42274741
A novel conserved evx1 enhancer links spinal interneuron morphology and cis-regulation from fish to mammals.Q42602673
In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundariesQ42639304
Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.Q42653537
The direct context of a hox retinoic acid response element is crucial for its activity.Q44405166
The amphioxus Hox cluster: characterization, comparative genomics, and evolution.Q44936893
Tri-phasic expression of posterior Hox genes during development of pectoral fins in zebrafish: implications for the evolution of vertebrate paired appendagesQ46475249
Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway.Q47713097
An autopodial-like pattern of Hox expression in the fins of a basal actinopterygian fish.Q47784218
Expression patterns of anterior Hox genes in the polychaete Chaetopterus: correlation with morphological boundariesQ47894473
Colinear and segmental expression of amphioxus Hox genesQ47936870
Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioicaQ48175053
The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during developmentQ48199087
Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammalsQ48251434
Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1.Q48365861
Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identityQ48394035
HOXA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS.Q49105366
De novo t(12;17)(p13.3;q21.3) translocation with a breakpoint near the 5' end of the HOXB gene cluster in a patient with developmental delay and skeletal malformations.Q51906495
Transgenic analysis of Hoxd gene regulation during digit development.Q51988368
Nuclear reorganisation and chromatin decondensation are conserved, but distinct, mechanisms linked to Hox gene activation.Q51996175
Nuclear re-organisation of the Hoxb complex during mouse embryonic development.Q52052528
Conserved expression domains for genes upstream and within the HoxA and HoxD clusters suggests a long-range enhancer existed before cluster duplication.Q52086203
Acquisition of Hox codes during gastrulation and axial elongation in the mouse embryo.Q52103471
An enhancer-titration effect induces digit-specific regulatory alleles of the HoxD cluster.Q52107075
Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs.Q52112403
Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells.Q52113171
A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects.Q52121441
Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head.Q52142969
Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing.Q52144089
Breaking colinearity in the mouse HoxD complex.Q52177304
Vertebrate hox gene regulation: clustering and/or colinearity?Q52182758
Elements both 5' and 3' to the murine Hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm.Q52192274
Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls.Q52201020
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1.Q52215015
Retinoic acid and homeobox gene regulation.Q52215432
Separate elements cause lineage restriction and specify boundaries of Hox-1.1 expressionQ52237113
The murine and Drosophila homeobox gene complexes have common features of organization and expression.Q52453645
Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes.Q52565016
Spatial regulation of homeobox gene fusions in the embryonic central nervous system of transgenic mice.Q54741360
Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formationQ59065602
Hox gene expression in teleost fins and the origin of vertebrate digitsQ59065867
Region-specific enhancers near two mammalian homeo box genes define adjacent rostrocaudal domains in the central nervous systemQ68087572
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expressionQ68321893
Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochronyQ71789867
P407language of work or nameEnglishQ1860
P921main subjecthomeoboxQ898769
regulatory sequenceQ3238407
developmental gene expression regulationQ70697639
multigene familyQ71148070
P304page(s)63-78
P577publication date2010-01-01
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titleControl of vertebrate Hox clusters by remote and global cis-acting regulatory sequences
Control of Vertebrate Hox Clusters by Remote and Global Cis-Acting Regulatory Sequences
P478volume689

Reverse relations

cites work (P2860)
Q34378106Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds
Q34256743Nipbl and mediator cooperatively regulate gene expression to control limb development
Q56269877Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A
Q28079793Split hand/foot malformation genetics supports the chromosome 7 copy segregation mechanism for human limb development

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