| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1050457660 |
| P356 | DOI | 10.1007/S11899-011-0108-8 |
| P698 | PubMed publication ID | 22200996 |
| P50 | author | Francois Delhommeau | Q53876560 |
| P2093 | author name string | Elodie Pronier | |
| P2860 | cites work | The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain | Q22065852 |
| The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes | Q22299206 | ||
| Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain | Q24299862 | ||
| Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 | Q24306181 | ||
| Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair | Q24309357 | ||
| Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 | Q24316558 | ||
| Cancer-associated IDH1 mutations produce 2-hydroxyglutarate | Q24320239 | ||
| The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid | Q24531866 | ||
| The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate | Q24605258 | ||
| JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis | Q24609999 | ||
| Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine | Q24614582 | ||
| Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies | Q24648438 | ||
| TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study | Q27851621 | ||
| TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics | Q27851661 | ||
| A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera | Q28241887 | ||
| Genomic DNA methylation: the mark and its mediators | Q28290773 | ||
| Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells | Q28478707 | ||
| Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification | Q28504641 | ||
| Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells | Q28504716 | ||
| TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis | Q28507642 | ||
| Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation | Q28508217 | ||
| Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice | Q28511594 | ||
| Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies | Q28591763 | ||
| TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity | Q28595004 | ||
| Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis | Q29614337 | ||
| Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders | Q29614510 | ||
| Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation | Q29615366 | ||
| The history of cancer epigenetics | Q29617273 | ||
| Cancer epigenetics comes of age | Q29617275 | ||
| Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation | Q29617398 | ||
| TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). | Q55036452 | ||
| Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance | Q58455666 | ||
| Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias | Q61772125 | ||
| Common 4q24 deletion in four cases of hematopoietic malignancy: early stem cell involvement? | Q81791345 | ||
| Analysis of the ten-eleven translocation 2 (TET2) gene in familial myeloproliferative neoplasms | Q84142205 | ||
| Mutation analysis of TET2, IDH1, IDH2 and ASXL1 in chronic myeloid leukemia | Q84261845 | ||
| Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia | Q84863988 | ||
| Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms | Q95779600 | ||
| A gain-of-function mutation of JAK2 in myeloproliferative disorders | Q29618851 | ||
| Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders | Q29618853 | ||
| Mutation in TET2 in myeloid cancers | Q29619292 | ||
| Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine | Q33922491 | ||
| Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. | Q34074931 | ||
| Myeloproliferative neoplasms: molecular pathophysiology, essential clinical understanding, and treatment strategies | Q34158356 | ||
| Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias | Q34162729 | ||
| Regulation of transcription and chromatin by methyl-CpG binding protein MBD1. | Q34460587 | ||
| Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. | Q34574880 | ||
| The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms | Q34612586 | ||
| MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia | Q34770384 | ||
| Acquired mutations in TET2 are common in myelodysplastic syndromes | Q34984094 | ||
| CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia. | Q35030952 | ||
| Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells | Q35071448 | ||
| The essentials of DNA methylation | Q35326024 | ||
| 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells | Q35557702 | ||
| Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors | Q35797589 | ||
| Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML. | Q36303442 | ||
| TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis | Q36303447 | ||
| Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates | Q36303456 | ||
| Chronic myelogenous leukemia, BCR-ABL1+. | Q37552486 | ||
| Mutational analysis in BCR-ABL-negative classic myeloproliferative neoplasms: impact on prognosis and therapeutic choices | Q37705374 | ||
| New mutations and pathogenesis of myeloproliferative neoplasms. | Q37886439 | ||
| Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission. | Q38343881 | ||
| Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA | Q39717028 | ||
| CXXC finger protein 1 is required for normal proliferation and differentiation of the PLB-985 myeloid cell line | Q40165492 | ||
| DNA methylation: a molecular lock | Q41441579 | ||
| How does DNA methylation repress transcription? | Q41653866 | ||
| Distribution of 5-hydroxymethylcytosine in different human tissues | Q41833660 | ||
| Clonal analysis of erythroid progenitors suggests that pegylated interferon alpha-2a treatment targets JAK2V617F clones without affecting TET2 mutant cells | Q43045807 | ||
| Mutations of ASXL1 gene in myeloproliferative neoplasms. | Q43456344 | ||
| MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients | Q44008600 | ||
| Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value | Q45088115 | ||
| Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms | Q45770967 | ||
| Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms | Q47960630 | ||
| Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm. | Q50574544 | ||
| Chromosomal abnormalities in transformed Ph-negative myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2 mutations. | Q53297206 | ||
| Deletions of the transcription factor Ikaros in myeloproliferative neoplasms. | Q54426186 | ||
| The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression. | Q54579216 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 57-64 | |
| P577 | publication date | 2012-03-01 | |
| P1433 | published in | Current hematologic malignancy reports | Q26842233 |
| P1476 | title | Role of TET2 mutations in myeloproliferative neoplasms | |
| P478 | volume | 7 |
| Q53121139 | FISH analysis for TET2 deletion in a cohort of 362 Brazilian myeloid malignancies: correlation with karyotype abnormalities. |
| Q27002361 | Mechanism and function of oxidative reversal of DNA and RNA methylation |
| Q38208010 | Molecular genetics of myelofibrosis and its associated disease phenotypes |
| Q38150711 | Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer |
| Q34786448 | Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription |
| Q37244379 | TETonic shift: biological roles of TET proteins in DNA demethylation and transcription |
| Q33877993 | The curious origins of angioimmunoblastic T-cell lymphoma |
| Q54161068 | [CALR gene mutation detection and clinical observation of 150 essential thrombocythemia patients]. |
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