Neither interleukin-4 receptor alpha expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis

scientific article published on 16 December 2008

Neither interleukin-4 receptor alpha expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1365-2567.2008.02987.X
P698PubMed publication ID19191917

P50authorHannah E ScalesQ62554100
P2093author name stringJames Alexander
Karin A Saunders
S McGowan
Catherine E Lawrence
Chesney E Michels
Frank Brombracher
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Heligmosomoides polygyrus: CD4+ but not CD8+ T cells regulate the IgE response and protective immunity in miceQ39243584
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IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.Q39461953
Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanismQ39527973
The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell functionQ39575789
Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastrointestinal nematode parasites.Q39586138
Villous atrophy and expulsion of intestinal Trichinella spiralis are mediated by T cellsQ40723252
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Host protective immunity to Trichinella spiralis in mice: activation of Th cell subsets and lymphokine secretion in mice expressing different response phenotypesQ41153397
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Conditional gene targeting in macrophages and granulocytes using LysMcre mice.Q44554898
IgE enhances parasite clearance and regulates mast cell responses in mice infected with Trichinella spiralisQ44714987
Mouse mast cell protease-1 is required for the enteropathy induced by gastrointestinal helminth infection in the mouse.Q44965234
IL-13 can substitute for IL-4 in the generation of dendritic cells for the induction of cytotoxic T lymphocytes and gene therapyQ45858329
B cell response to T helper cell subsets. II. Both the stage of T cell differentiation and the cytokines secreted determine the extent and nature of helper activityQ45961064
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.Q46899191
Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.Q50335911
Polarization of naive T cells into Th1 or Th2 by distinct cytokine-driven murine dendritic cell populations: implications for immunotherapy.Q53670466
Gastrointestinal nematode expulsion in IL-4 knockout mice is IL-13 dependent.Q54040787
A critical role for IL-13 in resistance to intestinal nematode infection.Q54142884
Invited review Intestinal nematode parasites, cytokines and effector mechanismsQ61781845
T lymphocyte dependent enteropathy in murine Trichinella spiralis infectionQ68102576
L3T4-positive T lymphoblasts are responsible for transfer of immunity to Trichinella spiralis in miceQ69874453
A critical role for stem cell factor and c-kit in host protective immunity to an intestinal helminthQ71163028
Increased intestinal muscle contractility and worm expulsion in nematode-infected miceQ73281346
Role of common cytokine receptor gamma chain (gamma(c))- and Jak3-dependent signaling in the proliferation and survival of murine mast cellsQ74296201
Differential functions of IL-4 receptor types I and II for dendritic cell maturation and IL-12 production and their dependency on GM-CSFQ74817245
IL-4-regulated enteropathy in an intestinal nematode infectionQ77353691
The role of IL-4, IL-13 and IL-4Ralpha in the development of protective and pathological responses to Trichinella spiralisQ79619623
Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cellsQ80209255
Intraepithelial NK cell-derived IL-13 induces intestinal pathology associated with nematode infectionQ81099280
IL-4 is more effective than IL-13 for in vitro differentiation of dendritic cells from peripheral blood mononuclear cellsQ81159338
P433issue1 Suppl
P921main subjectTrichinella spiralisQ730937
P304page(s)e385-94
P577publication date2008-12-16
P1433published inImmunologyQ15754984
P1476titleNeither interleukin-4 receptor alpha expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis
P478volume128

Reverse relations

cites work (P2860)
Q46258885A DNA vaccine co-expressing Trichinella spiralis MIF and MCD-1 with murine ubiquitin induces partial protective immunity in mice
Q38066119Cancer-related inflammation
Q48023702Coinfection with Clonorchis sinensis modulates murine host response against Trichinella spiralis infection
Q49347747Immunity to gastrointestinal nematode infections.
Q36727971Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance
Q27007951Macrophage proliferation, provenance, and plasticity in macroparasite infection
Q59280514Myeloid cell-specific expression of Ship1 regulates IL-12 production and immunity to helminth infection
Q33633305Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes.
Q34171430The vitamin D receptor and inducible nitric oxide synthase associated pathways in acquired resistance to Cooperia oncophora infection in cattle

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