| scholarly article | Q13442814 |
| P50 | author | Takashi Saito | Q42776201 |
| P2093 | author name string | Nobuyuki Takei | |
| Hiroyuki Nawa | |||
| Takaomi C Saido | |||
| Per Nilsson | |||
| Yukio Matsuba | |||
| Naomasa Kakiya | |||
| Satoshi Tsubuki | |||
| P2860 | cites work | The amyloid precursor protein: beyond amyloid | Q24680465 |
| Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo | Q24683214 | ||
| Structural basis for regulation of protein phosphatase 1 by inhibitor-2 | Q27646775 | ||
| The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 | ||
| Signaling through scaffold, anchoring, and adaptor proteins | Q28131792 | ||
| Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition | Q28143799 | ||
| Selectivity in neurotrophin signaling: theme and variations | Q28211196 | ||
| Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme | Q28216644 | ||
| Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease | Q28236160 | ||
| Metabolism of amyloid-beta peptide and Alzheimer's disease | Q28268316 | ||
| Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases | Q28505860 | ||
| Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade | Q33703262 | ||
| Casein kinase 2 dependent phosphorylation of neprilysin regulates receptor tyrosine kinase signaling to Akt | Q33721897 | ||
| Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease | Q33726762 | ||
| Somatostatin receptor 1 and 5 double knockout mice mimic neurochemical changes of Huntington's disease transgenic mice | Q34017941 | ||
| Oligomeric amyloid-{beta} inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioning | Q34251263 | ||
| Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy | Q35928266 | ||
| Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease. | Q36139139 | ||
| Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease | Q36579852 | ||
| Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. | Q37273874 | ||
| Cracking the phosphatase code: docking interactions determine substrate specificity | Q37649281 | ||
| Potent amyloidogenicity and pathogenicity of Aβ43. | Q39513749 | ||
| Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo | Q40199218 | ||
| Effects of neprilysin chimeric proteins targeted to subcellular compartments on amyloid beta peptide clearance in primary neurons | Q40564428 | ||
| The Trk family of neurotrophin receptors | Q40590908 | ||
| Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. | Q40594671 | ||
| Real-time analysis of clathrin-mediated endocytosis during cell migration | Q40672535 | ||
| Alzheimer's disease: a central role for amyloid | Q40701623 | ||
| Intracellular signaling pathways activated by neurotrophic factors | Q41132714 | ||
| Alzheimer's disease as proteolytic disorders: anabolism and catabolism of beta-amyloid | Q41751572 | ||
| Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies | Q41818257 | ||
| Brain neprilysin activity and susceptibility to transgene-induced Alzheimer amyloidosis | Q46761107 | ||
| Constitutively active protein phosphatase 1alpha causes Rb-dependent G1 arrest in human cancer cells | Q46808819 | ||
| Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders | Q46977355 | ||
| Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death | Q48110123 | ||
| Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging | Q48463232 | ||
| Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function. | Q48569616 | ||
| Metabolic regulation of brain Abeta by neprilysin | Q48869458 | ||
| Neprilysin content is reduced in Alzheimer brain areas | Q48929943 | ||
| Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation | Q48960635 | ||
| Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide | Q49145268 | ||
| Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain. | Q52541645 | ||
| Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques. | Q53203663 | ||
| Synergy in tumor suppression by direct interaction of Neutral Endopeptidase with PTEN | Q57364534 | ||
| NGF and other growth factors induce an association between ERK1 and the NGF receptor, gp140prototrk | Q61640803 | ||
| Autolytic Transition of μCalpain upon Activation as Resolved by Antibodies Distinguishing between the Pre- and Post-Autolysis Forms1 | Q68159073 | ||
| P433 | issue | 35 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 29362-29372 | |
| P577 | publication date | 2012-07-05 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Cell surface expression of the major amyloid-β peptide (Aβ)-degrading enzyme, neprilysin, depends on phosphorylation by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) and dephosphorylation by protein phosphatase 1a | |
| P478 | volume | 287 |
| Q60045614 | 5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer's disease |
| Q27321649 | A novel effect of MARCKS phosphorylation by activated PKC: the dephosphorylation of its serine 25 in chick neuroblasts |
| Q37182136 | Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicity |
| Q27334336 | Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration |
| Q28086779 | Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging II: over-expression of neprilysin plays an essential role |
| Q48825325 | C-type natriuretic peptide in Parkinson's disease: reduced secretion and response to deprenyl |
| Q37205562 | Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells |
| Q33695622 | HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway. |
| Q90340346 | Humanin analogue, HNG, inhibits platelet activation and thrombus formation by stabilizing platelet microtubules |
| Q40966227 | Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo |
| Q35172084 | PKCε promotes HuD-mediated neprilysin mRNA stability and enhances neprilysin-induced Aβ degradation in brain neurons |
| Q37089706 | Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease. |
| Q94201022 | Treatment with Akebia Saponin D Ameliorates Aβ-Induced Memory Impairment and Neurotoxicity in Rats |
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