LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature

scientific article published on 07 July 2010

LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1000376
P698PubMed publication ID20610648

P50authorTom H M OttenhoffQ87817901
Jan W DrijfhoutQ114408770
P2093author name stringPieter S Hiemstra
Jaap T van Dissel
Peter H Nibbering
Anne M van der Does
Henry Beekhuizen
Bep Ravensbergen
Tim Vos
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1442-1449
P577publication date2010-07-07
P1433published inJournal of ImmunologyQ3521441
P1476titleLL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature
P478volume185

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cites work (P2860)
Q99635253A Novel Peptide Antibiotic, Pro10-1D, Designed from Insect Defensin Shows Antibacterial and Anti-Inflammatory Activities in Sepsis Models
Q34519899A novel approach for emerging and antibiotic resistant infections: Innate defense regulators as an agnostic therapy
Q36607002A novel role of a lipid species, sphingosine-1-phosphate, in epithelial innate immunity.
Q52592947Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds.
Q55515233Antimicrobial and Chemotactic Activity of Scorpion-Derived Peptide, ToAP2, against Mycobacterium massiliensis.
Q41747279Antimicrobial effects of helix D-derived peptides of human antithrombin III
Q35941306Antimicrobial peptide LL-37 along with peptidoglycan drive monocyte polarization toward CD14(high)CD16(+) subset and may play a crucial role in the pathogenesis of psoriasis guttata
Q48176521Autoantigens ADAMTSL5 and LL37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes
Q40367916Bacterial subversion of cAMP signalling inhibits cathelicidin expression, which is required for innate resistance to Mycobacterium tuberculosis.
Q91868554Cathelicidin Contributes to the Restriction of Leishmania in Human Host Macrophages
Q33700171Cathelicidin host defence peptide augments clearance of pulmonary Pseudomonas aeruginosa infection by its influence on neutrophil function in vivo
Q26777983Cathelicidin impact on inflammatory cells
Q89635635Cathelicidin preserves intestinal barrier function in polymicrobial sepsis
Q64082972Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action
Q58739098Cathelicidins: Immunomodulatory Antimicrobials
Q37806640Contribution of neutrophils to acute lung injury
Q42372846Defining Genome-Wide Expression and Phenotypic Contextual Cues in Macrophages Generated by Granulocyte/Macrophage Colony-Stimulating Factor, Macrophage Colony-Stimulating Factor, and Heat-Killed Mycobacteria.
Q39848642Differential capacity for complement receptor-mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte
Q34454677Endogenous cathelicidin production limits inflammation and protective immunity to Mycobacterium avium in mice.
Q59608361Evaluation of Platelet-Rich Plasma and Neutrophil Antimicrobial Extract as Two Autologous Blood-Derived Agents
Q47429893Exogenous murine antimicrobial peptide CRAMP significantly exacerbates Ovalbumin-induced airway inflammation but ameliorates oxazolone-induced intestinal colitis in BALB/c mice
Q36607908Extracellular traps and macrophages: new roles for the versatile phagocyte.
Q33749859Generation of Novel Bone Forming Cells (Monoosteophils) from the Cathelicidin-Derived Peptide LL-37 Treated Monocytes
Q50130264Heterogeneity of Bovine Peripheral Blood Monocytes
Q58785420Host Defense Peptide LL-37-Mediated Chemoattractant Properties, but Not Anti-Inflammatory Cytokine IL-1RA Production, Is Selectively Controlled by Cdc42 Rho GTPase G Protein-Coupled Receptors and JNK Mitogen-Activated Protein Kinase
Q87514916Human cathelicidin LL-37 and its derivative IG-19 regulate interleukin-32-induced inflammation
Q42531590Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation.
Q42285768Human β defensin-3 induces chemokines from monocytes and macrophages: diminished activity in cells from HIV-infected persons
Q38162670Immune modulation by multifaceted cationic host defense (antimicrobial) peptides
Q90194919Immunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13-31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic Index
Q40365863Interspecies cathelicidin comparison reveals divergence in antimicrobial activity, TLR modulation, chemokine induction and regulation of phagocytosis
Q33988247Involvement of the janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis.
Q36281314LL-37 immunomodulatory activity during Mycobacterium tuberculosis infection in macrophages
Q34341371LL-37 modulates human neutrophil responses to influenza A virus
Q64230065LL37 Inhibits Infection via Directly Binding to the Fungus and Preventing Excessive Inflammation
Q37332300Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease
Q36688480Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis
Q38604832Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function
Q64277502Myeloid cell-derived LL-37 promotes lung cancer growth by activating Wnt/β-catenin signaling
Q36553792Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages
Q36984720Neutrophil-derived cathelicidin promotes adhesion of classical monocytes
Q85002734New insights into cathelicidin modulation of adaptive immunity
Q28082379On the Functional Overlap between Complement and Anti-Microbial Peptides
Q46237880P17, an Original Host Defense Peptide from Ant Venom, Promotes Antifungal Activities of Macrophages through the Induction of C-Type Lectin Receptors Dependent on LTB4-Mediated PPARγ Activation.
Q38859591P2X7 Receptor Regulates Internalization of Antimicrobial Peptide LL-37 by Human Macrophages That Promotes Intracellular Pathogen Clearance
Q49506021Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease.
Q40594099Pathogenesis of antimicrobial peptides LL-37 and CpG-ODN in ANCA associated vasculitis
Q36941335Protective effect of in ovo treatment with the chicken cathelicidin analog D-CATH-2 against avian pathogenic E. coli
Q28071636Purinergic signalling in autoimmunity: A role for the P2X7R in systemic lupus erythematosus?
Q37783287Radiotracers for fungal infection imaging
Q36424863Regulation of YKL-40 expression by corticosteroids: effect on pro-inflammatory macrophages in vitro and its modulation in COPD in vivo.
Q34287544SOCS3 deficiency promotes M1 macrophage polarization and inflammation.
Q64989366Serum concentrations of antimicrobial peptide cathelicidin LL-37 in patients with bacterial lung infections.
Q35783492Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial
Q35004988Structure-activity studies and therapeutic potential of host defense peptides of human thrombin
Q83285857The antimicrobial peptide hLF1-11 drives monocyte-dendritic cell differentiation toward dendritic cells that promote antifungal responses and enhance Th17 polarization
Q48279568The burn wound inflammatory response is influenced by midazolam
Q35992127The immunology of host defence peptides: beyond antimicrobial activity
Q35802798The microbiome at the pulmonary alveolar niche and its role in Mycobacterium tuberculosis infection
Q90641553The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production

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