Antimicrobial effects of helix D-derived peptides of human antithrombin III

scientific article published on 8 September 2014

Antimicrobial effects of helix D-derived peptides of human antithrombin III is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M114.570465
P932PMC publication ID4207992
P698PubMed publication ID25202017

P50authorRavi K V BhongirQ85276206
Praveen PapareddyQ58658896
P2093author name stringArtur Schmidtchen
Martin Malmsten
Matthias Mörgelin
Martina Kalle
P2860cites workHistidine-rich glycoprotein protects from systemic Candida infectionQ24313429
Highly selective end-tagged antimicrobial peptides derived from PRELPQ28476835
Proteolysis of human thrombin generates novel host defense peptidesQ29871443
Cell-surface heparan sulfate proteoglycan-mediated regulation of human neutrophil migration by the serpin antithrombin III.Q31835224
Antimicrobial activity of human prion protein is mediated by its N-terminal regionQ33509013
Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitmentQ33526956
Antithrombin replacement in patients with sepsis and septic shockQ33636213
Sulfated polysaccharide-directed recruitment of mammalian host proteins: a novel strategy in microbial pathogenesisQ34001696
C-terminal peptides of tissue factor pathway inhibitor are novel host defense moleculesQ34107512
Antimicrobial proteins and peptides in host defenseQ34223226
Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trialQ34518326
Antithrombin III in Sepsis. New evidences and open questionsQ34656175
Antithrombin: a new look at the actions of a serine protease inhibitorQ35004303
Interactions between Coagulation and InflammationQ35585029
Heparin-binding domains in vascular biologyQ35825233
Regulation of thrombin activity--pharmacologic and structural aspectsQ36720111
Serpins in thrombosis, hemostasis and fibrinolysisQ36884340
Proteolytic activation transforms heparin cofactor II into a host defense moleculeQ36914757
Activation of the complement system generates antibacterial peptidesQ37695583
Host defense peptides and their antimicrobial-immunomodulatory dualityQ37786712
Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinityQ38293560
Intracellular receptor for human host defense peptide LL-37 in monocytesQ39824888
Therapeutic potential of HDPs as immunomodulatory agentsQ39907609
Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.Q40321158
An overview of the mechanism of action of antithrombin and its inherited deficiency states.Q40753967
Coagulation inhibitor substitution during sepsisQ40990081
Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of actionQ41456132
Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in ratsQ42199996
Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficienciesQ44075032
Human antithrombin III-derived heparin-binding peptide, a novel heparin antagonistQ44597765
Antimicrobial activities of heparin-binding peptidesQ44629787
Probing the heparin-binding domain of human antithrombin III with V8 proteaseQ45302282
Comparison of the helix-coil transition of a titrating polypeptide in aqueous solutions and at the air-water interfaceQ46505055
Domain 5 of high molecular weight kininogen is antibacterialQ46642869
Therapeutic applications of antithrombin concentrates in systemic inflammatory disorders.Q47851737
Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study.Q48020761
Heparin binding protein is increased in chronic leg ulcer fluid and released from granulocytes by secreted products of Pseudomonas aeruginosa.Q51642205
Engineering D-helix of antithrombin in alpha-1-proteinase inhibitor confers antiinflammatory properties on the chimeric serpin.Q53621386
Bacterial killing by heparin-binding peptides from PRELP and thrombospondin.Q54464584
A heparin binding site in antithrombin III. Identification, purification, and amino acid sequenceQ68182117
Computed circular dichroism spectra for the evaluation of protein conformationQ71225133
Attenuating effect of antithrombin III on the fibrinolytic activation and microvascular derangement in rat gastric mucosaQ72381283
The thrombin antagonist hirudin fails to inhibit endotoxin-induced leukocyte/endothelial cell interaction and microvascular perfusion failureQ73226945
Recombinant human antithrombin III improves survival and attenuates inflammatory responses in baboons lethally challenged with Escherichia coliQ73426853
Antithrombin inhibits lipopolysaccharide-induced tissue factor and interleukin-6 production by mononuclear cells, human umbilical vein endothelial cells, and whole bloodQ73436045
Measurement of free radicals and NO by chemiluminescence to identify the reperfusion injury in renal transplantationQ74060471
Antithrombin III inhibits nuclear factor kappaB activation in human monocytes and vascular endothelial cellsQ74097923
Degradation of antiproteinases, complement and fibronectin in chronic leg ulcersQ74211300
Effect of antithrombin III supplementation on inflammatory response in patients with severe sepsisQ77168946
Apolipoprotein A-I binds and inhibits the human antibacterial/cytotoxic peptide LL-37Q77630845
LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signatureQ84541002
P433issue43
P407language of work or nameEnglishQ1860
P304page(s)29790-29800
P577publication date2014-09-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleAntimicrobial effects of helix D-derived peptides of human antithrombin III
P478volume289

Reverse relations

cites work (P2860)
Q33737867Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism.
Q54267933An ecoimmunological approach to study evolutionary and ancient links between coagulation, complement and Innate immunity.
Q90005460Antimicrobial Peptide JH-3 Effectively Kills Salmonella enterica Serovar Typhimurium Strain CVCC541 and Reduces Its Pathogenicity in Mice
Q89950751Antithrombin: An anticoagulant, anti-inflammatory and antibacterial serpin
Q48502611Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions
Q47126929Immunohaemostasis: a new view on haemostasis during sepsis
Q40936407NLF20: an antimicrobial peptide with therapeutic potential against invasive Pseudomonas aeruginosa infection.
Q28597180Vertebrate TFPI-2 C-terminal peptides exert therapeutic applications against Gram-negative infections

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