C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules

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C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.127019
P8608Fatcat IDrelease_qroen7dis5hhjkerfalhymnpva
P932PMC publication ID2934703
P698PubMed publication ID20592020

P50authorArtur SchmidtchenQ88461456
Martina KalleQ114138745
Victoria RydengårdQ114138751
Katarina LundqvistQ114138777
Barbara AlbigerQ114138787
Martin MalmstenQ58780071
P2093author name stringMatthias Mörgelin
Praveen Papareddy
Gopinath Kasetty
P2860cites workHistidine-rich glycoprotein protects from systemic Candida infectionQ24313429
Proteolytic inactivation of tissue factor pathway inhibitor by bacterial omptinsQ24658383
Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitorQ27637118
Antimicrobial peptides of multicellular organismsQ28131811
Defensins: antimicrobial peptides of innate immunityQ28204453
Cathelicidins, multifunctional peptides of the innate immunityQ28205494
LL-37, the only human member of the cathelicidin family of antimicrobial peptidesQ28241675
Tissue factor pathway inhibitor: structure, biology and involvement in diseaseQ28279765
Tissue factor pathway inhibitor blocks cellular effects of endotoxin by binding to endotoxin and interfering with transfer to CD14Q73436759
A novel degradation pathway of tissue factor pathway inhibitor: incorporation into fibrin clot and degradation by thrombinQ73686459
Proteolysis of tissue factor pathway inhibitor (TFPI) by plasmin: effect on TFPI activityQ77366940
Apolipoprotein A-I binds and inhibits the human antibacterial/cytotoxic peptide LL-37Q77630845
Identification of heparin/heparan sulfate interacting protein as a major broad-spectrum antimicrobial protein in lung and small intestineQ80771027
Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitorQ28284809
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?Q29547675
Proteolysis of human thrombin generates novel host defense peptidesQ29871443
Amphipathic, alpha-helical antimicrobial peptidesQ33994626
Antimicrobial proteins and peptides in host defenseQ34223226
Molecular diversity in gene-encoded, cationic antimicrobial polypeptides.Q34595498
What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses?Q35143463
The contact system--a novel branch of innate immunity generating antibacterial peptidesQ35191114
Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shockQ35611991
The relationship between peptide structure and antibacterial activityQ35690395
Anti-microbial peptides: from invertebrates to vertebrates.Q35806874
Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibioticsQ36126588
Alpha-helical antimicrobial peptides--using a sequence template to guide structure-activity relationship studiesQ36469872
Advances in antimicrobial peptide immunobiologyQ36493474
The haemostatic role of tissue factor pathway inhibitor.Q36977056
Interaction between the coagulation and complement systemQ37331658
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cellsQ37628594
Activation of the complement system generates antibacterial peptidesQ37695583
Alternatively spliced isoforms of tissue factor pathway inhibitorQ37696775
CAP37, a neutrophil-derived multifunctional inflammatory mediatorQ40550510
Differential proteinase expression by Pseudomonas aeruginosa derived from chronic leg ulcersQ40658136
The role of the C-terminal domain in the inhibitory functions of tissue factor pathway inhibitorQ40910806
Composition effect on peptide interaction with lipids and bacteria: variants of C3a peptide CNY21.Q41047319
Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa.Q41628125
Structural and functional characterization of tissue factor pathway inhibitor following degradation by matrix metalloproteinase-8.Q43002265
Designed low amphipathic peptides with alpha-helical propensity exhibiting antimicrobial activity via a lipid domain formation mechanismQ43181764
Antimicrobial activities of heparin-binding peptidesQ44629787
Ultrasensitive assays for endogenous antimicrobial polypeptidesQ45416239
Fragmented tissue factor pathway inhibitor (TFPI) and TFPI C-terminal peptides eliminate serum-resistant Escherichia coli from blood culturesQ46357600
Comparison of the helix-coil transition of a titrating polypeptide in aqueous solutions and at the air-water interfaceQ46505055
Domain 5 of high molecular weight kininogen is antibacterialQ46642869
Identification and characterization of a very low density lipoprotein receptor-binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activityQ47247959
Heparin binding protein is increased in chronic leg ulcer fluid and released from granulocytes by secreted products of Pseudomonas aeruginosa.Q51642205
The antibacterial activity of peptides derived from human beta-2 glycoprotein I is inhibited by protein H and M1 protein from Streptococcus pyogenes.Q53509908
Antimicrobial peptides derived from growth factors.Q54442631
Low temperature embedding with Lowicryl resins: two new formulations and some applicationsQ69928849
Computed circular dichroism spectra for the evaluation of protein conformationQ71225133
P433issue36
P407language of work or nameEnglishQ1860
P304page(s)28387-28398
P577publication date2010-06-30
P1433published inJournal of Biological ChemistryQ867727
P1476titleC-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules
P478volume285

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cites work (P2860)
Q53712921A new cryptic cationic antimicrobial peptide from human apolipoprotein E with antibacterial activity and immunomodulatory effects on human cells.
Q33927961A peptide of heparin cofactor II inhibits endotoxin-mediated shock and invasive Pseudomonas aeruginosa infection.
Q33737867Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism.
Q37881747Alternatively spliced tissue factor pathway inhibitor: functional implications
Q54267933An ecoimmunological approach to study evolutionary and ancient links between coagulation, complement and Innate immunity.
Q38447222Antifungal activities of peptides derived from domain 5 of high-molecular-weight kininogen
Q36439097Antimicrobial Peptide CMA3 Derived from the CA-MA Hybrid Peptide: Antibacterial and Anti-inflammatory Activities with Low Cytotoxicity and Mechanism of Action in Escherichia coli
Q54344153Antimicrobial activity of peptides derived from human ß-amyloid precursor protein.
Q41747279Antimicrobial effects of helix D-derived peptides of human antithrombin III
Q37954721Antimicrobial peptides: key components of the innate immune system
Q35222585Discovery of modulators of HIV-1 infection from the human peptidome
Q36254797Effect of Regular Exercise on Inflammation Induced by Drug-resistant Staphylococcus aureus 3089 in ICR mice
Q55123953Endogenous tissue factor pathway inhibitor has a limited effect on host defence in murine pneumococcal pneumonia.
Q50980605Endothelial cell-anchored tissue factor pathway inhibitor regulates tumor metastasis to the lung in mice.
Q35636201Feasibility and Safety of Local Treatment with Recombinant Human Tissue Factor Pathway Inhibitor in a Rat Model of Streptococcus pneumoniae Pneumonia
Q28476835Highly selective end-tagged antimicrobial peptides derived from PRELP
Q27331817Host defense peptides of thrombin modulate inflammation and coagulation in endotoxin-mediated shock and Pseudomonas aeruginosa sepsis
Q26741309Multiple Functions of the New Cytokine-Based Antimicrobial Peptide Thymic Stromal Lymphopoietin (TSLP)
Q35071276Neutrophil serine proteases in antibacterial defense
Q36914757Proteolytic activation transforms heparin cofactor II into a host defense molecule
Q58750549TFPI-2 Protects Against Gram-Negative Bacterial Infection
Q35067228The TFPI-2 derived peptide EDC34 improves outcome of gram-negative sepsis.
Q89601715Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products
Q43878141Thymic stromal lymphopoietin exerts antimicrobial activities
Q34541158Tissue factor pathway inhibitor 2 is found in skin and its C-terminal region encodes for antibacterial activity
Q37971520Tissue factor pathway inhibitor: structure-function
Q64052051Transcriptomic analysis reveals insights into deep-sea adaptations of the dominant species, Shinkaia crosnieri (Crustacea: Decapoda: Anomura), inhabiting both hydrothermal vents and cold seeps
Q28597180Vertebrate TFPI-2 C-terminal peptides exert therapeutic applications against Gram-negative infections

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