Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

scientific article published on 20 January 2013

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.2534
P698PubMed publication ID23334791

P50authorHergen SpitsQ89927093
P2093author name stringWillem A Bemelman
Kees Weijer
Nicolas Legrand
Sybren L Meijer
Anje A te Velde
Christianne J Buskens
Charlotte P Peters
Jenny M Mjösberg
Jochem H Bernink
Hulda S Hreggvidsdottir
Marius Munneke
Sigrid E Heinsbroek
P2860cites workThe transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cellsQ39260231
The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.Q40990833
Functional Differences between Human NKp44(-) and NKp44(+) RORC(+) Innate Lymphoid CellsQ41838358
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.Q41862330
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.Q41904687
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineageQ42786917
Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cellsQ42915172
A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cellsQ43905966
Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.Q45200144
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defenseQ46197286
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cellsQ46231038
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.Q47898451
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.Q52586488
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.Q53590422
Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.Q53888112
The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentiumQ57194289
Lineage Relationship Analysis of RORγt+Innate Lymphoid CellsQ57520258
Regulation of Cytokine Secretion in Human CD127+ LTi-like Innate Lymphoid Cells by Toll-like Receptor 2Q58478673
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127Q58478714
Lymphotoxin alphabeta is expressed on recently activated naive and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiationQ78109594
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammationQ83678198
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161Q84933191
A novel transcription factor, T-bet, directs Th1 lineage commitmentQ22253874
Systemically dispersed innate IL-13-expressing cells in type 2 immunityQ24623563
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunityQ24630261
Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22Q24655076
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune systemQ24680733
Transcriptional control of innate lymphoid cellsQ27005868
Anti-interleukin-12 antibody for active Crohn's diseaseQ28292686
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunityQ28299539
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient miceQ28594052
Inflammatory bowel diseaseQ29615500
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cellsQ29619771
Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticityQ33934522
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.Q34152180
Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseasesQ34181228
Innate lymphoid cells: emerging insights in development, lineage relationships, and functionQ34245256
Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trialQ34275637
Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytesQ34591589
Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunityQ35624378
Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.Q35634065
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virusQ35872309
Evidence for discrete stages of human natural killer cell differentiation in vivoQ36228536
Innate lymphoid cell interactions with microbiota: implications for intestinal health and diseaseQ36390314
Development of human lymphoid cellsQ36427345
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient miceQ37111353
T-bet in disease.Q37891668
IL-23-responsive innate lymphoid cells are increased in inflammatory bowel diseaseQ38423061
P433issue3
P304page(s)221-229
P577publication date2013-01-20
P1433published inNature ImmunologyQ1071725
P1476titleHuman type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
P478volume14

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Q35581734TNF-α Producing Innate Lymphoid Cells (ILCs) Are Increased in Active Celiac Disease and Contribute to Promote Intestinal Atrophy in Mice
Q57038953Targeting of the nasal mucosa by Japanese encephalitis virus for non-vector-borne transmission
Q42375565Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease
Q38984610The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease
Q37419561The Gdac1 locus modifies spontaneous and Salmonella-induced colitis in mice deficient in either Gpx2 or Gpx1 gene
Q92239566The Influence of Innate Lymphoid Cells and Unconventional T Cells in Chronic Inflammatory Lung Disease
Q92538718The Interplay Between Innate Lymphoid Cells and the Tumor Microenvironment
Q89486269The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis
Q90401345The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype
Q33790954The Role of Innate Lymphoid Cells in Immune-Mediated Liver Diseases
Q64102236The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection
Q38319907The biology of innate lymphoid cells
Q57039150The brave new world of innate lymphoid cells
Q49925661The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation.
Q40791214The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing
Q97530878The interplay between innate lymphoid cells and T cells
Q35065019The microbiome and regulation of mucosal immunity
Q26740079The origin and role of innate lymphoid cells in the lung
Q90589872The pathogenic role of innate lymphoid cells in autoimmune-related and inflammatory skin diseases
Q89665184The role of innate lymphoid cells in response to microbes at mucosal surfaces
Q38115440The role of the immune system in governing host-microbe interactions in the intestine
Q89282567The roles for innate lymphoid cells in the human immune system
Q34105699The roles of innate lymphoid cells in the development of asthma
Q42262891The transcription Factor AHR prevents the differentiation of a stage 3 innate lymphoid cell subset to natural killer cells.
Q33634144The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells
Q38478216The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.
Q59792624Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
Q50133227Tissue-Resident Cytolytic Innate Lymphocytes in Cancer.
Q64090873Tissue-resident Eomes NK cells are the major innate lymphoid cell population in human infant intestine
Q38089253Tissue-specific effector functions of innate lymphoid cells.
Q36358937Transcription factor networks directing the development, function, and evolution of innate lymphoid effectors
Q100395393Transcription tipping points for T follicular helper cell and T-helper 1 cell fate commitment
Q89621143Transcriptional and Functional Programming of Decidual Innate Lymphoid Cells
Q38525099Transcriptional regulation of innate lymphoid cell fate.
Q52879143Transcriptionally defining ILC heterogeneity in humans.
Q33799561Transcriptome analysis reveals similarities between human blood CD3- CD56bright cells and mouse CD127+ innate lymphoid cells.
Q94521908Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer
Q64065227Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation
Q28829881Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells
Q90000019True Detective: Unraveling Group 1 Innate Lymphocyte Heterogeneity
Q91168567Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn's disease
Q28066387Type 1 Innate Lymphoid Cell Biology: Lessons Learnt from Natural Killer Cells
Q64251722Type 2 Innate Lymphoid Cells in Liver and Gut: From Current Knowledge to Future Perspectives
Q57181216Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation
Q90388993Type 3 Immunity during Clostridioides difficile Infection: Too Much of a Good Thing?
Q36299851Type 3 innate lymphoid cell depletion is mediated by TLRs in lymphoid tissues of simian immunodeficiency virus-infected macaques
Q39402904Type two innate lymphoid cells: the Janus cells in health and disease.
Q97546129Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells
Q36694912Unique Eomes(+) NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy.
Q38865721Vitamins A and D have antagonistic effects on expression of effector cytokines and gut-homing integrin in human innate lymphoid cells.
Q38809547What rheumatologists need to know about innate lymphocytes
Q28079656When Insult Is Added to Injury: Cross Talk between ILCs and Intestinal Epithelium in IBD
Q56873607Will the real ILC1 please stand up?
Q91530400c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies
Q90388552c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program
Q89625928c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells

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