Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes

scientific article

Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes is …
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scholarly articleQ13442814

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P356DOI10.1016/J.IMMUNI.2010.10.017
P932PMC publication ID3042726
P698PubMed publication ID21093318
P5875ResearchGate publication ID49624563

P50authorAndreas DiefenbachQ56954454
P2093author name stringCarl F Ware
Robert Thimme
Cedric Vonarbourg
Daniela Finke
Elina A Kiss
Klaus Schwarz
Ulrich Pannicke
Manfred Hönig
Bertram Bengsch
Arthur Mortha
Viet L Bui
Christoph Hölscher
Melanie Flach
Pedro P Hernandez
Thomas Hoyler
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Systemically dispersed innate IL-13-expressing cells in type 2 immunityQ24623563
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunityQ24630261
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22Q24648620
Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22Q24655076
Interleukin-23 drives innate and T cell-mediated intestinal inflammationQ24677051
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locusQ24797230
Requirement for RORgamma in thymocyte survival and lymphoid organ developmentQ28139666
An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cellsQ28235728
A genome-wide association study identifies IL23R as an inflammatory bowel disease geneQ28270603
Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cellsQ28271481
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunityQ28299539
Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node developmentQ28585776
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient miceQ28594052
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasisQ29547656
NK cell recognitionQ29615107
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cellsQ29619771
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursorsQ33656197
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.Q33854381
Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticityQ33934522
RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cellsQ34441341
Intestinal lamina propria dendritic cell subsets have different origin and functions.Q35001346
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.Q35002543
Evidence for discrete stages of human natural killer cell differentiation in vivoQ36228536
Lymphoid neogenesis in chronic inflammatory diseases.Q36405080
Shared gamma(c) subunit within the human interleukin-7 receptor complex. A molecular basis for the pathogenesis of X-linked severe combined immunodeficiency.Q37362415
Hidden talents of natural killers: NK cells in innate and adaptive immunityQ37381928
Regulatory lymphocytes and intestinal inflammation.Q37419380
Late developmental plasticity in the T helper 17 lineageQ39265291
Innate and adaptive interleukin-22 protects mice from inflammatory bowel diseaseQ39902875
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.Q41904687
Origin of the lamina propria dendritic cell networkQ42117974
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skinQ42604162
Isolation of NK cells and NK-like cells from the intestinal lamina propriaQ43771245
Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.Q45918490
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defenseQ46197286
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cellsQ46231038
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.Q46461994
Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells.Q51985115
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.Q52586488
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.Q52590127
The IL-7 signaling pathway regulates lymph node development independent of peripheral lymphocytes.Q52599046
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.Q53590422
Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues.Q54652657
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127Q58478714
Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cellsQ73838320
Innate lymphocytes induce inflammatory bowel diseaseQ84494196
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)736-751
P577publication date2010-11-01
P1433published inImmunityQ6005457
P1476titleRegulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes
P478volume33

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Q50133227Tissue-Resident Cytolytic Innate Lymphocytes in Cancer.
Q92572255Tissue-resident cytotoxic innate lymphoid cells in tumor immunosurveillance
Q37684372Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells
Q35694098Tissue-resident natural killer cells and their potential diversity
Q38089253Tissue-specific effector functions of innate lymphoid cells.
Q24629126Transcription factor RORα is critical for nuocyte development
Q52874734Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.
Q38192561Transcription factors controlling development and function of innate lymphoid cells
Q35064355Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
Q38525099Transcriptional regulation of innate lymphoid cell fate.
Q33799561Transcriptome analysis reveals similarities between human blood CD3- CD56bright cells and mouse CD127+ innate lymphoid cells.
Q40689375Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells.
Q28829881Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells
Q90000019True Detective: Unraveling Group 1 Innate Lymphocyte Heterogeneity
Q35245316Tumor necrosis factor superfamily in innate immunity and inflammation
Q36180686Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation
Q38218882Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin
Q39763196Vitamin A Controls the Presence of RORγ+ Innate Lymphoid Cells and Lymphoid Tissue in the Small Intestine
Q89167812Why Innate Lymphoid Cells?
Q37486151Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity
Q41348746Zbtb1 controls NKp46+ ROR-gamma-T+ innate lymphoid cell (ILC3) development
Q50673833[Innate lymphoid cells: new players of the mucosal immune response].
Q52765682[Innate lymphoid cells].
Q90388552c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program
Q89625928c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells

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