The carboxy-terminal domain of connexin 43 (CT-Cx43) modulates the expression of p53 by altering miR-125b expression in low-grade human breast cancers

scientific article published on 03 September 2015

The carboxy-terminal domain of connexin 43 (CT-Cx43) modulates the expression of p53 by altering miR-125b expression in low-grade human breast cancers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S13402-015-0240-X
P698PubMed publication ID26335100

P2093author name stringMahboob Ul Hussain
Nisar Ahmad Chowdri
Raihana Maqbool
Rehana Ismail
Rabiya Rashid
Saif Niaz
P2860cites workThymidylate synthase expression and p21(WAF1)/p53 phenotype of colon cancers identify patients who may benefit from 5-fluorouracil based therapy.Q54394304
p53 — Master and CommanderQ59238393
miRNAs in head and neck cancer revisitedQ63459877
The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growthQ73085587
MiR-429 up-regulation induces apoptosis and suppresses invasion by targeting Bcl-2 and SP-1 in esophageal carcinomaQ87351725
Differential expression of miR-139, miR-486 and miR-21 in breast cancer patients sub-classified according to lymph node statusQ87401555
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Real-time quantification of microRNAs by stem-loop RT-PCRQ24535510
The complexity of p53 modulation: emerging patterns from divergent signalsQ28284854
p53 mutations in human cancersQ28302973
Circulating MiR-125b as a marker predicting chemoresistance in breast cancerQ28482362
DNA damage activates p53 through a phosphorylation-acetylation cascadeQ29616294
Physiological and physiopathological aspects of connexins and communicating gap junctions in spermatogenesisQ33856936
Activation of p53 by oncogenesQ33872973
Internal ribosomal entry site (IRES) activity generates endogenous carboxyl-terminal domains of Cx43 and is responsive to hypoxic conditionsQ33947209
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miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-α, CCNJ, and MEGF9.Q35009302
MiR-125b acts as an oncogene in glioblastoma cells and inhibits cell apoptosis through p53 and p38MAPK-independent pathwaysQ35028282
Regulation of connexin expressionQ36344530
The role of connexins in controlling cell growth and gene expressionQ36803102
Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusionQ37142419
P53 protein in proliferation, repair and apoptosis of cellsQ37720224
Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of TumorigenesisQ37903701
Micro-RNAs (miRNAs): genomic organisation, biogenesis and mode of actionQ38012626
p53 mutations in cancerQ38069463
MicroRNAs and human diseases: diagnostic and therapeutic potentialQ38184973
Good guy or bad guy: the opposing roles of microRNA 125b in cancerQ38207752
miR-125b regulates side population in breast cancer and confers a chemoresistant phenotypeQ39162646
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcomeQ39484788
Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: its effect on cell proliferation and implication for therapy.Q40476195
Involvement of p53 in cell differentiation and developmentQ41592444
Dual functions for connexins: Cx43 regulates growth independently of gap junction formationQ42823532
Gene expression alterations in connexin null mice extend beyond the gap junction.Q47599681
A novel saliva-based microRNA biomarker panel to detect head and neck cancers.Q53025206
The chemosensitivity of testicular germ cell tumors.Q53059668
The cancer genome: from structure to function.Q53087702
Pathological implications of Cx43 down-regulation in human colon cancer.Q53237826
P433issue6
P304page(s)443-451
P577publication date2015-09-03
P1433published inCellular OncologyQ2160503
P1476titleThe carboxy-terminal domain of connexin 43 (CT-Cx43) modulates the expression of p53 by altering miR-125b expression in low-grade human breast cancers
P478volume38

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cites work (P2860)
Q55011586Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer.
Q52716310Connexins: Synthesis, Post-Translational Modifications, and Trafficking in Health and Disease.
Q37613777Gap junctions and cancer: communicating for 50 years
Q31157753SpidermiR: An R/Bioconductor Package for Integrative Analysis with miRNA Data
Q52563269The Novel Roles of Connexin Channels and Tunneling Nanotubes in Cancer Pathogenesis.
Q90369241Tumor-suppressor microRNA-139-5p restrains bladder cancer cell line ECV-304 properties via targeting Connexin 43
Q52932292microRNA-761 induces aggressive phenotypes in triple-negative breast cancer cells by repressing TRIM29 expression.

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