Glycolysis and EZH2 boost T cell weaponry against tumors

scientific article published on 01 January 2016

Glycolysis and EZH2 boost T cell weaponry against tumors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.3346
P698PubMed publication ID26681461

P2093author name stringChristoph Hess
Glenn R Bantug
P2860cites workPosttranscriptional control of T cell effector function by aerobic glycolysisQ24606942
The immune contexture in human tumours: impact on clinical outcomeQ29620667
Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in miceQ33824617
Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancerQ34017104
A central role for Notch in effector CD8(+) T cell differentiationQ34517022
T cell metabolic fitness in antitumor immunityQ35371293
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.Q36054460
Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.Q36386431
MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1betaQ39703169
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer ProgressionQ41437712
Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switchQ42275889
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cellsQ44997676
Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancerQ57152489
P433issue1
P304page(s)41-42
P577publication date2016-01-01
P1433published inNature ImmunologyQ1071725
P1476titleGlycolysis and EZH2 boost T cell weaponry against tumors
P478volume17

Reverse relations

cites work (P2860)
Q39245946Structure of the PRC2 complex and application to drug discovery.
Q46382588The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).

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