human | Q5 |
P1960 | Google Scholar author ID | e25-lgUAAAAJ |
P6634 | LinkedIn personal profile ID | christina-leslie-578629a3 |
P856 | official website | https://www.mskcc.org/research/ski/labs/christina-leslie |
P496 | ORCID iD | 0000-0002-4571-5910 |
P69 | educated at | University of California, Berkeley | Q168756 |
P108 | employer | Memorial Sloan Kettering Cancer Center | Q1808012 |
P734 | family name | Leslie | Q26736517 |
Leslie | Q26736517 | ||
Leslie | Q26736517 | ||
P735 | given name | Christina | Q1083457 |
Christina | Q1083457 | ||
P106 | occupation | researcher | Q1650915 |
Q127079648 | A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL |
Q127071933 | A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells |
Q35930311 | A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner |
Q31016573 | A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL). |
Q36888933 | A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance |
Q112716530 | A unified atlas of CD8 T cell dysfunctional states in cancer and infection |
Q92610505 | ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer |
Q127398104 | Abstract 3370: Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers |
Q127401458 | Abstract 3384: Genome-wide epigenetic and transcriptional comparison of CD8 T cell functional states between mouse models of cancer and chronic viral infection |
Q127399897 | Abstract 4346: PI3K pathway mediated splicing defects in ER+ breast cancers |
Q127400341 | Abstract 949: ARID1A is a critical regulator of luminal identity and therapeutic response in estrogen receptor-positive breast cancer |
Q96122992 | Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells |
Q41209124 | Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism |
Q27313925 | Affinity regression predicts the recognition code of nucleic acid–binding proteins |
Q40883914 | An allelic series of miR-17 ∼ 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron |
Q24614360 | An atlas of the Epstein-Barr virus transcriptome and epigenome reveals host-virus regulatory interactions |
Q36373890 | An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data. |
Q34599128 | Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S |
Q99207765 | Author Correction: FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes |
Q36478257 | BCL6 positively regulates AID and germinal center gene expression via repression of miR-155. |
Q124877862 | Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants |
Q92579095 | BindSpace decodes transcription factor binding signals by large-scale sequence embedding |
Q34993852 | CSF-1R inhibition alters macrophage polarization and blocks glioma progression |
Q42114048 | Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells. |
Q36409649 | Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia |
Q127152457 | Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation |
Q46060358 | Chromatin states define tumour-specific T cell dysfunction and reprogramming. |
Q90287857 | Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers |
Q33371114 | Combining classifiers for improved classification of proteins from sequence or structure |
Q39216584 | Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein |
Q34548301 | Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans |
Q45966217 | Computational searches for splicing signals. |
Q39177304 | Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs |
Q36642197 | Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing. |
Q33658568 | Determining frequent patterns of copy number alterations in cancer |
Q41849095 | Dichotomous splicing signals in exon flanks |
Q127080204 | Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate. |
Q42007308 | Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation |
Q58798130 | Epigenetic control of innate and adaptive immune memory |
Q42380537 | Ets transcription factor GABP controls T cell homeostasis and immunity |
Q93053616 | FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes |
Q91770771 | FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation |
Q104471323 | FXR mediates T cell-intrinsic responses to reduced feeding during infection |
Q24596097 | Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia |
Q35975049 | Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells |
Q127078522 | Global 3' UTR Sequencing in Multiple Myeloma (MM) |
Q42705414 | Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap |
Q112722311 | Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses |
Q36298067 | GuideScan software for improved single and paired CRISPR guide RNA design |
Q24305018 | Heme controls the regulation of protein tyrosine kinases Jak2 and Src |
Q96123867 | High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down |
Q93216336 | HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells |
Q93344389 | IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation |
Q127147079 | IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells |
Q127148924 | IKZF2, a Novel Target of MSI2 RNA-Binding Protein Plays an Oncogenic Role in Myeloid Leukemia |
Q47604842 | ILC1 Confer Early Host Protection at Initial Sites of Viral Infection |
Q35881570 | Ibrutinib resistance in chronic lymphocytic leukemia |
Q36283789 | Identifying remote protein homologs by network propagation |
Q35031404 | In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA. |
Q28578955 | Induction of specific microRNAs inhibits cutaneous wound healing |
Q36213745 | Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma |
Q36584991 | Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer |
Q112289512 | KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix |
Q31116138 | Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data |
Q34439395 | Linking signaling pathways to transcriptional programs in breast cancer. |
Q36611010 | MSI2 is required for maintaining activated myelodysplastic syndrome stem cells |
Q41266256 | Memory of Inflammation in Regulatory T Cells |
Q127062220 | MiR-28 Silencing In Germinal Center-Derived Lymphomas |
Q33730792 | MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas. |
Q127106478 | Microrna Mediated Regulation of Hematopoietic Stem Cell Aging |
Q42620879 | Mismatch string kernels for discriminative protein classification |
Q48479167 | Motif-based protein ranking by network propagation |
Q91530405 | Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12 |
Q127150872 | Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program |
Q39465157 | Multitask learning improves prediction of cancer drug sensitivity |
Q36981038 | NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A |
Q91555143 | Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells |
Q58726524 | Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection |
Q64083920 | PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression |
Q34554022 | PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D. |
Q37622585 | Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs. |
Q112721970 | Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility |
Q36298062 | Prediction of potent shRNAs with a sequential classification algorithm |
Q34444041 | Profile-based string kernels for remote homology detection and motif extraction |
Q62491962 | Profile-based string kernels for remote homology detection and motif extraction |
Q115779111 | Programme of self-reactive innate-like T cell-mediated cancer immunity |
Q34301600 | Protein backbone angle prediction with machine learning approaches. |
Q33244577 | Protein ranking by semi-supervised network propagation |
Q33695754 | Protein ranking: from local to global structure in the protein similarity network |
Q127149419 | RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program |
Q40059019 | Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure |
Q114107374 | SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes |
Q35643204 | SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps |
Q24561544 | Sequence information for the splicing of human pre-mRNA identified by support vector machine classification |
Q112721356 | Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets |
Q112702650 | Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation |
Q64887305 | Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. |
Q40328357 | Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia |
Q28914780 | Target mRNA abundance dilutes microRNA and siRNA activity |
Q33683959 | The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma |
Q101569404 | The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries |
Q91495449 | The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types |
Q127082080 | Therapeutic Transgene Expression From Genomic Safe Harbors In Patient-Specific Induced Pluripotent Stem Cells |
Q91045843 | Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function |
Q91024501 | Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity |
Q38320111 | Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting |
Q28914781 | Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs |
Q37309705 | Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression |
Q52715419 | Widespread intronic polyadenylation diversifies immune cell transcriptomes. |
Q59054299 | Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. |
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