Christina S Leslie

Computational biologist

Christina S Leslie is …
instance of (P31):
humanQ5

External links are
P1960Google Scholar author IDe25-lgUAAAAJ
P6634LinkedIn personal profile IDchristina-leslie-578629a3
P856official websitehttps://www.mskcc.org/research/ski/labs/christina-leslie
P496ORCID iD0000-0002-4571-5910

P69educated atUniversity of California, BerkeleyQ168756
P108employerMemorial Sloan Kettering Cancer CenterQ1808012
P734family nameLeslieQ26736517
LeslieQ26736517
LeslieQ26736517
P735given nameChristinaQ1083457
ChristinaQ1083457
P106occupationresearcherQ1650915

Reverse relations

author (P50)
Q127079648A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL
Q127071933A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells
Q35930311A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner
Q31016573A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Q36888933A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance
Q112716530A unified atlas of CD8 T cell dysfunctional states in cancer and infection
Q92610505ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer
Q127398104Abstract 3370: Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers
Q127401458Abstract 3384: Genome-wide epigenetic and transcriptional comparison of CD8 T cell functional states between mouse models of cancer and chronic viral infection
Q127399897Abstract 4346: PI3K pathway mediated splicing defects in ER+ breast cancers
Q127400341Abstract 949: ARID1A is a critical regulator of luminal identity and therapeutic response in estrogen receptor-positive breast cancer
Q96122992Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
Q41209124Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
Q27313925Affinity regression predicts the recognition code of nucleic acid–binding proteins
Q40883914An allelic series of miR-17 ∼ 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron
Q24614360An atlas of the Epstein-Barr virus transcriptome and epigenome reveals host-virus regulatory interactions
Q36373890An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data.
Q34599128Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
Q99207765Author Correction: FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes
Q36478257BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.
Q124877862Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
Q92579095BindSpace decodes transcription factor binding signals by large-scale sequence embedding
Q34993852CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Q42114048Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells.
Q36409649Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia
Q127152457Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation
Q46060358Chromatin states define tumour-specific T cell dysfunction and reprogramming.
Q90287857Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers
Q33371114Combining classifiers for improved classification of proteins from sequence or structure
Q39216584Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein
Q34548301Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans
Q45966217Computational searches for splicing signals.
Q39177304Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs
Q36642197Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.
Q33658568Determining frequent patterns of copy number alterations in cancer
Q41849095Dichotomous splicing signals in exon flanks
Q127080204Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate.
Q42007308Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation
Q58798130Epigenetic control of innate and adaptive immune memory
Q42380537Ets transcription factor GABP controls T cell homeostasis and immunity
Q93053616FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes
Q91770771FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation
Q104471323FXR mediates T cell-intrinsic responses to reduced feeding during infection
Q24596097Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Q35975049Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells
Q127078522Global 3' UTR Sequencing in Multiple Myeloma (MM)
Q42705414Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap
Q112722311Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
Q36298067GuideScan software for improved single and paired CRISPR guide RNA design
Q24305018Heme controls the regulation of protein tyrosine kinases Jak2 and Src
Q96123867High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down
Q93216336HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells
Q93344389IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation
Q127147079IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells
Q127148924IKZF2, a Novel Target of MSI2 RNA-Binding Protein Plays an Oncogenic Role in Myeloid Leukemia
Q47604842ILC1 Confer Early Host Protection at Initial Sites of Viral Infection
Q35881570Ibrutinib resistance in chronic lymphocytic leukemia
Q36283789Identifying remote protein homologs by network propagation
Q35031404In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA.
Q28578955Induction of specific microRNAs inhibits cutaneous wound healing
Q36213745Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma
Q36584991Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer
Q112289512KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix
Q31116138Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data
Q34439395Linking signaling pathways to transcriptional programs in breast cancer.
Q36611010MSI2 is required for maintaining activated myelodysplastic syndrome stem cells
Q41266256Memory of Inflammation in Regulatory T Cells
Q127062220MiR-28 Silencing In Germinal Center-Derived Lymphomas
Q33730792MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas.
Q127106478Microrna Mediated Regulation of Hematopoietic Stem Cell Aging
Q42620879Mismatch string kernels for discriminative protein classification
Q48479167Motif-based protein ranking by network propagation
Q91530405Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12
Q127150872Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program
Q39465157Multitask learning improves prediction of cancer drug sensitivity
Q36981038NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A
Q91555143Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells
Q58726524Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection
Q64083920PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression
Q34554022PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.
Q37622585Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs.
Q112721970Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
Q36298062Prediction of potent shRNAs with a sequential classification algorithm
Q34444041Profile-based string kernels for remote homology detection and motif extraction
Q62491962Profile-based string kernels for remote homology detection and motif extraction
Q115779111Programme of self-reactive innate-like T cell-mediated cancer immunity
Q34301600Protein backbone angle prediction with machine learning approaches.
Q33244577Protein ranking by semi-supervised network propagation
Q33695754Protein ranking: from local to global structure in the protein similarity network
Q127149419RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program
Q40059019Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure
Q114107374SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes
Q35643204SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps
Q24561544Sequence information for the splicing of human pre-mRNA identified by support vector machine classification
Q112721356Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets
Q112702650Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation
Q64887305Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Q40328357Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
Q28914780Target mRNA abundance dilutes microRNA and siRNA activity
Q33683959The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma
Q101569404The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries
Q91495449The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types
Q127082080Therapeutic Transgene Expression From Genomic Safe Harbors In Patient-Specific Induced Pluripotent Stem Cells
Q91045843Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function
Q91024501Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity
Q38320111Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting
Q28914781Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
Q37309705Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression
Q52715419Widespread intronic polyadenylation diversifies immune cell transcriptomes.
Q59054299Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia.

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