Alterations in mRNA profiles of trastuzumab‑resistant Her‑2‑positive breast cancer

scientific article published on 07 May 2018

Alterations in mRNA profiles of trastuzumab‑resistant Her‑2‑positive breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2018.8981
P932PMC publication ID6059662
P698PubMed publication ID29750305

P2093author name stringLi Li
Yan Sun
Bin Zhao
Yang Zhao
Haitao Niu
Long Sheng
Dongfang Huang
P2860cites workEstrogen receptors in breast carcinogenesis and endocrine therapyQ38272598
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Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment aloneQ44595949
Bcl-2 expression predicts local relapse for early-stage breast cancer receiving conserving surgery and radiotherapyQ46564173
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SOX11 promotes tumor angiogenesis through transcriptional regulation of PDGFA in mantle cell lymphoma.Q48284944
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TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumabQ59565353
Apoptosis and Bbcl-2 expression in gastric carcinomas: correlation withclinicopathological variables, p53 expression, cell proliferation and prognosisQ77716906
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BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy receivedQ24610409
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.Q27824819
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancerQ27851414
Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targetsQ28140238
Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cellsQ28201813
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High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpressionQ35709435
Adjuvant trastuzumab in HER2-positive breast cancerQ35710898
High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma.Q35878937
Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy.Q36021424
Prospective Biomarker Analysis of the Randomized CHER-LOB Study Evaluating the Dual Anti-HER2 Treatment With Trastuzumab and Lapatinib Plus Chemotherapy as Neoadjuvant Therapy for HER2-Positive Breast CancerQ36064908
Mechanisms of trastuzumab resistance and their clinical implications.Q36355193
Whole-transcriptome analysis links trastuzumab sensitivity of breast tumors to both HER2 dependence and immune cell infiltrationQ36414012
Multicenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal therapy and without chemotherapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer: TBCRC 006Q36810717
BCL2 as a Subtype-Specific Prognostic Marker for Breast CancerQ37316599
Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancerQ37633741
Prognostic Influence of BCL2 on Molecular Subtypes of Breast CancerQ37735963
P4510describes a project that usesCytoscapeQ3699942
P433issue1
P304page(s)139-146
P577publication date2018-05-07
P1433published inMolecular Medicine ReportsQ26842180
P1476titleAlterations in mRNA profiles of trastuzumab‑resistant Her‑2‑positive breast cancer
P478volume18

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