SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells

scientific article published on 01 August 2018

SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1210/EN.2017-03243
P932PMC publication ID6693047
P698PubMed publication ID29873699

P2093author name stringZhijie Chang
Chao Sun
Nicolas Musi
Yuguang Shi
Jia Nie
P2860cites workPAK signalling in neuronal physiologyQ24318480
Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-CellsQ24337361
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The GTPase Rab37 Participates in the Control of Insulin ExocytosisQ34797941
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EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.Q35236262
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SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signalingQ37117860
The AMP-regulated kinase family: enigmatic targets for diabetes therapyQ37210623
Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretionQ37357925
LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolismQ37543834
Glucagon-like peptide 1 stimulates insulin secretion via inhibiting RhoA/ROCK signaling and disassembling glucotoxicity-induced stress fibersQ38954331
Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretionQ40348059
Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cellsQ40596974
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Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activityQ41700861
LKB1 regulates pancreatic beta cell size, polarity, and functionQ41870049
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SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signalsQ43071847
Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in miceQ43266332
Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretionQ44449615
Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.Q52102307
Neurotrophic and neuroprotective properties of exendin-4 in adult rat dorsal root ganglion neurons: involvement of insulin and RhoA.Q53486609
The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activityQ59097192
A role for Rho GTPases and cell–cell adhesion in single-cell motility in vivoQ59314649
Stimulation of release of insulin by an extract of intestinal mucosaQ72781759
Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cellsQ80636222
Activation of SAD kinase by Ca2+/calmodulin-dependent protein kinase kinaseQ80832336
P433issue8
P304page(s)3036-3047
P577publication date2018-08-01
P1433published inEndocrinologyQ3054009
P1476titleSAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells
P478volume159

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