TRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells

scientific article published on 28 June 2018

TRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JAUT.2018.06.003
P932PMC publication ID6108920
P698PubMed publication ID29960834

P50authorJames A PearsonQ57339799
F. Susan WongQ63411298
Elke GüldenQ85326434
P2093author name stringJian Peng
Zhiguang Zhou
Li Wen
Ningwen Tai
Monika Majewska-Szczepanik
Chen Chao
P2860cites workThe role of the intestinal microbiota in type 1 diabetes mellitusQ35884681
Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in HumansQ36004640
NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets.Q36056835
Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturationQ36300342
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetesQ36323689
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusionQ36945852
TLR9 deficiency promotes CD73 expression in T cells and diabetes protection in nonobese diabetic mice.Q37210998
Microbial antigen mimics activate diabetogenic CD8 T cells in NOD miceQ37272130
Mucosal Prevalence and Interactions with the Epithelium Indicate Commensalism of Sutterella spp.Q37366316
Effects of the gut microbiota on obesity and glucose homeostasisQ37847381
Changes of regulatory T cells, transforming growth factor-beta and interleukin-10 in patients with type 1 diabetes mellitus: A systematic review and meta-analysisQ38920811
Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and InfectionQ39097028
Time trends in the incidence of type 1 diabetes in Finnish children: a cohort studyQ40088313
The intestinal proteome of diabetic and control children is enriched with different microbial and host proteinsQ40304529
TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetesQ41936111
Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturationQ41937286
T-lymphocyte clone specific for pancreatic islet antigenQ46335815
Compromised gut microbiota networks in children with anti-islet cell autoimmunityQ46922105
Trends in childhood type 1 diabetes incidence in Europe during 1989-2008: evidence of non-uniformity over time in rates of increaseQ46972336
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathwaysQ48219736
CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cellsQ58063831
The Role of Toll-Like Receptors 3 and 9 in the Development of Autoimmune Diabetes in NOD MiceQ59276520
Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetesQ80813712
Toward defining the autoimmune microbiome for type 1 diabetesQ24629032
Innate immunity and intestinal microbiota in the development of Type 1 diabetesQ24647312
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathwayQ28592087
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequencesQ29615050
UPARSE: highly accurate OTU sequences from microbial amplicon readsQ29616627
Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic miceQ30644510
Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitisQ33258217
Molecular inventory of faecal microflora in patients with Crohn's diseaseQ33497564
Role of the microbiota in immunity and inflammationQ33752553
Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentationQ33970555
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetesQ34063601
The microbiota in adaptive immune homeostasis and diseaseQ34533142
Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control studyQ34596660
Toll-like receptor 3 is critical for coxsackievirus B4-induced type 1 diabetes in female NOD mice.Q34982303
Toll-like receptor 4 deficiency accelerates the development of insulin-deficient diabetes in non-obese diabetic miceQ35005601
Long term effect of gut microbiota transfer on diabetes developmentQ35157830
Ablation of tumor necrosis factor is associated with decreased inflammation and alterations of the microbiota in a mouse model of inflammatory bowel disease.Q35182119
Aberrant gut microbiota composition at the onset of type 1 diabetes in young childrenQ35188386
The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetesQ35557877
The gut microbiota and Type 1 Diabetes.Q35655645
Microbiota regulates type 1 diabetes through Toll-like receptorsQ35718048
P921main subjecttype-1 diabetesQ124407
dendritic cellQ506253
P304page(s)57-65
P577publication date2018-06-28
P1433published inJournal of AutoimmunityQ15716783
P1476titleTRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells
P478volume93