Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

scientific article published on 01 February 2020

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S13395-020-0221-2
P932PMC publication ID6995146
P698PubMed publication ID32007101

P50authorAngus LindsayQ50991524
Dawn A LoweQ59688933
P2093author name stringJames M Ervasti
David D Thomas
James S Hodges
Cory W Baumann
Razvan L Cornea
William M Southern
Samantha L Yuen
Robyn T Rebbeck
P2860cites workDystrophin expression following the transplantation of normal muscle precursor cells protects mdx muscle from contraction-induced damageQ84585433
High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release ChannelsQ88589870
Neopterin/7,8-dihydroneopterin is elevated in Duchenne muscular dystrophy patients and protects mdx skeletal muscle functionQ88785440
Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibitionQ91593994
Plasmalemma Function Is Rapidly Restored in Mdx Muscle after Eccentric ContractionsQ92637741
Variable cytoplasmic actin expression impacts the sensitivity of different dystrophin-deficient mdx skeletal muscles to eccentric contractionQ92818986
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscleQ24308714
The dystrophin complex forms a mechanically strong link between the sarcolemma and costameric actinQ28145442
Dystrophin: the protein product of the Duchenne muscular dystrophy locusQ29618077
Microtubules underlie dysfunction in duchenne muscular dystrophy.Q30557507
Duchenne dystrophy: Electron microscopic findings pointing to a basic or early abnormality in the plasma membrane of the muscle fiberQ30951467
High-throughput FRET assay yields allosteric SERCA activatorsQ34393960
Expression of full-length utrophin prevents muscular dystrophy in mdx miceQ34482808
Determinants of the repeated-bout effect after lengthening contractionsQ35204675
SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse modelsQ35572589
A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophyQ36151226
Dystrophin protects the sarcolemma from stresses developed during muscle contractionQ36259954
Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.Q36273863
Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx miceQ36324105
Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic DisordersQ36650350
Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.Q36968852
Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type miceQ37139061
Microtubule binding distinguishes dystrophin from utrophinQ37711984
Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells.Q39033560
Eliminating Nox2 reactive oxygen species production protects dystrophic skeletal muscle from pathological calcium influx assessed in vivo by manganese-enhanced magnetic resonance imagingQ39459441
Overexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction-induced damageQ41118342
Characteristics of lengthening contractions associated with injury to skeletal muscle fibersQ41471206
Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.Q42149020
Prosurvival Factors Improve Functional Engraftment of Myogenically Converted Dermal Cells into Dystrophic Skeletal Muscle.Q42391300
Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractionsQ43258728
Susceptibility to sarcomere injury induced by single stretches of maximally activated muscles of mdx mice.Q44722909
Acute failure of action potential conduction in mdx muscle reveals new mechanism of contraction-induced force loss.Q44985983
Effects of stretch-activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse.Q45140549
A highly functional mini-dystrophin/GFP fusion gene for cell and gene therapy studies of Duchenne muscular dystrophyQ45857200
Insulin-like growth factor-I analogue protects muscles of dystrophic mdx mice from contraction-mediated damageQ46528995
N-Acetylcysteine ameliorates skeletal muscle pathophysiology in mdx miceQ46765634
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacyQ47665947
Streptomycin reduces stretch-induced membrane permeability in muscles from mdx miceQ50475477
Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins.Q54241942
Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weaknessQ57191111
Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cellsQ58722435
Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscleQ59799234
Injury to muscle fibres after single stretches of passive and maximally stimulated muscles in miceQ70917677
Increased susceptibility of EDL muscles from mdx mice to damage induced by contractions with stretchQ72102757
Eccentric contraction-induced injury in normal and hindlimb-suspended mouse soleus and EDL musclesQ72464292
Mechanical factors in the initiation of eccentric contraction-induced injury in rat soleus muscleQ72578539
Rapid recovery following contraction-induced injury to in situ skeletal muscles in mdx miceQ74425819
The effects of stretch parameters on eccentric exercise-induced damage to toad skeletal muscleQ74534142
The relation between force and speed in muscular contractionQ80330090
Branched fibers in dystrophic mdx muscle are associated with a loss of force following lengthening contractionsQ80475156
P433issue1
P304page(s)3
P577publication date2020-02-01
P1433published inSkeletal MuscleQ27723741
P1476titleMechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators
P478volume10

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