scholarly article | Q13442814 |
P50 | author | Grace E Stutzmann | Q89597810 |
Robert A. Marr | Q127690892 | ||
P2093 | author name string | Clark A Briggs | |
Virginie Bottero | |||
Oded Singer | |||
John McDaid | |||
Sarah Mustaly-Kalimi | |||
Sean Schrank | |||
Aiden Houcek | |||
Deanna Brinks | |||
P2860 | cites work | Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells | Q21245229 |
Calsenilin reverses presenilin-mediated enhancement of calcium signaling | Q22254629 | ||
Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau | Q24320124 | ||
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice | Q24604235 | ||
Rapid single-step induction of functional neurons from human pluripotent stem cells | Q26269862 | ||
Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies | Q26769957 | ||
Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore. | Q27303076 | ||
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease | Q28241772 | ||
Alzheimer's disease: the amyloid cascade hypothesis | Q29547160 | ||
Neuronal calcium signaling | Q29614727 | ||
Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models | Q50690364 | ||
Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus. | Q52060326 | ||
Calcium Signaling Deficits in Glia and Autophagic Pathways Contributing to Neurodegenerative Disease. | Q52690972 | ||
Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer's disease | Q61445489 | ||
Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences | Q64084123 | ||
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling | Q90389062 | ||
The neuropathological diagnosis of Alzheimer's disease | Q92374124 | ||
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology | Q29617284 | ||
Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers | Q30557695 | ||
Identification of beta-secretase (BACE1) substrates using quantitative proteomics | Q33521280 | ||
NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice | Q34149384 | ||
Alzheimer's disease risk genes and mechanisms of disease pathogenesis | Q34425904 | ||
Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits | Q34509797 | ||
Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease | Q34532864 | ||
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease | Q34988301 | ||
Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease | Q35658184 | ||
Tau, tangles, and Alzheimer's disease | Q35992144 | ||
APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases | Q36325304 | ||
The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid | Q36582358 | ||
Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model | Q36799810 | ||
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease | Q36934762 | ||
The pathogenesis of Alzheimers disease is it a lifelong "calciumopathy"? | Q36954095 | ||
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective | Q37095615 | ||
The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid | Q37112633 | ||
Molecular mechanisms of amyloid oligomers toxicity | Q38005284 | ||
The very many faces of presenilins and the γ-secretase complex. | Q38090514 | ||
Function and dysfunction of presenilin | Q38150941 | ||
Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors | Q38947646 | ||
Emerging pathways driving early synaptic pathology in Alzheimer's disease | Q38962140 | ||
Interleukin-1β orchestrates underlying inflammatory responses in microglia via Krüppel-like factor 4. | Q39118762 | ||
Neurofibrillary tangles and Alzheimer's disease. | Q40842017 | ||
Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes | Q41609588 | ||
Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice | Q41979914 | ||
Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease. | Q42635301 | ||
Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors | Q42738430 | ||
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. | Q44728737 | ||
Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice. | Q45916530 | ||
Influence of solubilization and AD-mutations on stability and structure of human presenilins. | Q47118640 | ||
Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation. | Q47345806 | ||
Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families | Q47692392 | ||
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus | Q48349302 | ||
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice. | Q48546084 | ||
LIM domain only 4 (LMO4) regulates calcium-induced calcium release and synaptic plasticity in the hippocampus. | Q48601209 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 3 | |
P577 | publication date | 2020-02-04 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology | |
P478 | volume | 21 |
Search more.