NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice

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NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice is …
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scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.2474-10.2010
P932PMC publication ID2944253
P698PubMed publication ID20826675

P2093author name stringGrace E Stutzmann
Megan B Miller
Ivan Goussakov
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Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.Q48546084
Three-dimensional organization of smooth endoplasmic reticulum in hippocampal CA1 dendrites and dendritic spines of the immature and mature rat.Q48823521
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Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutationsQ24301868
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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memoryQ24645499
Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behaviorQ24645994
Presenilins are essential for regulating neurotransmitter releaseQ24653851
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Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocardQ28565619
Inositol 1,4,5 trisphosphate receptor and chromogranin B are concentrated in different regions of the hippocampusQ28569736
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathwayQ28854318
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Dysfunctional intracellular calcium homoeostasis: a central cause of neurodegeneration in Alzheimer's diseaseQ34305302
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Calcium dysregulation, IP3 signaling, and Alzheimer's diseaseQ34399955
Calcium dyshomeostasis and intracellular signalling in Alzheimer's diseaseQ34988301
Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer's diseaseQ35022592
Presence and functional significance of presynaptic ryanodine receptorsQ35184822
Dynamic multiphoton imaging: a live view from cells to systemsQ36011389
Presynaptic calcium stores and synaptic transmissionQ36140951
Distribution of inositol-1,4,5-trisphosphate receptor isotypes and ryanodine receptor isotypes during maturation of the rat hippocampusQ36453053
Blockade of IP3-mediated SK channel signaling in the rat medial prefrontal cortex improves spatial working memoryQ36510456
P433issue36
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
P304page(s)12128-12137
P577publication date2010-09-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleNMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice
P478volume30

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