| P2093 | author name string | Seongmin Lee | |
| | Hala Ouzon-Shubeita | |
| | Caroline K Vilas | |
| P2860 | cites work | Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs | Q24644933 |
| | Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation | Q27650580 |
| | DNA Polymerase Substrate Specificity: SIDE CHAIN MODULATION OF THE"A-RULE" | Q27657443 |
| | Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly | Q27672742 |
| | Binary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesion | Q27676274 |
| | Stereospecific Formation of a Ternary Complex of (S)-α,β-Fluoromethylene-dATP with DNA Pol β | Q27677140 |
| | Amino Acid Substitution in the Active Site of DNA Polymerase β Explains the Energy Barrier of the Nucleotidyl Transfer Reaction | Q27678004 |
| | Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. | Q27678705 |
| | Observing a DNA Polymerase Choose Right from Wrong | Q27678932 |
| | Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy | Q27678933 |
| | Metal-Dependent Conformational Activation Explains Highly Promutagenic Replication across O6-Methylguanine by Human DNA Polymerase β | Q27682793 |
| | Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine | Q27684466 |
| | Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism | Q27742804 |
| | Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents | Q28191144 |
| | DNA polymerase beta expression differences in selected human tumors and cell lines | Q28198269 |
| | The status of platinum anticancer drugs in the clinic and in clinical trials | Q28286605 |
| | A role for DNA polymerase beta in mutagenic UV lesion bypass | Q28570436 |
| | Cellular processing of platinum anticancer drugs | Q29617899 |
| | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | Q33947166 |
| | Nucleotide excision repair from site-specifically platinum-modified nucleosomes. | Q51836720 |
| | In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors. | Q52720551 |
| | Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. | Q54038050 |
| | Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta. | Q54055057 |
| | Elevated DNA polymerase beta activity in a cis-diamminedichloroplatinum(II) resistant P388 murine leukemia cell line. | Q54391218 |
| | The side effects of platinum-based chemotherapy drugs: a review for chemists | Q55952286 |
| | DNA repair pathways and cisplatin resistance: an intimate relationship | Q58699219 |
| | Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta | Q81386042 |
| | Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases | Q92003319 |
| | Cisplatin in cancer therapy: molecular mechanisms of action | Q34098163 |
| | Factors Contributing to Aromatic Stacking in Water: Evaluation in the Context of DNA. | Q34144275 |
| | C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency | Q34350141 |
| | Error-prone translesion synthesis mediates acquired chemoresistance | Q34376054 |
| | Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β. | Q34467599 |
| | The resurgence of platinum-based cancer chemotherapy | Q34649255 |
| | Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents | Q34774332 |
| | Molecular mechanisms of resistance and toxicity associated with platinating agents | Q35758048 |
| | Magnesium-induced assembly of a complete DNA polymerase catalytic complex. | Q35792408 |
| | Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes | Q36105474 |
| | Cisplatin/carboplatin cross-resistance in ovarian cancer | Q36467911 |
| | Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta | Q36557917 |
| | Direct cellular responses to platinum-induced DNA damage | Q36800400 |
| | A comprehensive survey of the mutagenic impact of common cancer cytotoxics | Q36886849 |
| | Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers | Q36958682 |
| | Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance | Q37172320 |
| | Molecular mechanisms of cisplatin resistance | Q37926477 |
| | Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts | Q38321258 |
| | Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair | Q40176489 |
| | Mutator phenotype of BCR--ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase beta | Q40951632 |
| | The effect of DNA structure on the catalytic efficiency and fidelity of human DNA polymerase beta on templates with platinum-DNA adducts | Q43548141 |
| | Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity. | Q43833668 |
| | Involvement of DNA polymerase beta in DNA replication and mutagenic consequences | Q43876611 |
| | In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic | Q45770163 |
| | Overexpression of DNA polymerase β: a genomic instability enhancer process | Q49816580 |
| | Acquired chemotherapy resistance in ovarian cancer. | Q49896015 |
| P275 | copyright license | Creative Commons Attribution 2.0 Generic | Q19125117 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P1104 | number of pages | 15 | |
| P304 | page(s) | 937-951 | |
| P577 | publication date | 2020-03-01 | |
| P1433 | published in | Biochemical Journal | Q864221 |
| P1476 | title | Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion | |
| P478 | volume | 477 | |