| scholarly article | Q13442814 |
| P50 | author | Fumihiko Urano | Q89723298 |
| P2093 | author name string | David W Piston | |
| Damien Abreu | |||
| Zeno Lavagnino | |||
| Kelly Kries | |||
| Rie Asada | |||
| John M P Revilla | |||
| P2860 | cites work | Sex differences in the development of diabetes in mice with deleted wolframin (Wfs1) gene. | Q51388010 |
| Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome | Q81449869 | ||
| Neurologic features and genotype-phenotype correlation in Wolfram syndrome | Q83739551 | ||
| A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome) | Q22003951 | ||
| Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells | Q24299603 | ||
| WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum | Q24304081 | ||
| TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver | Q24304147 | ||
| GAGE: generally applicable gene set enrichment for pathway analysis | Q24645628 | ||
| Wolfram Syndrome: Diagnosis, Management, and Treatment | Q26770241 | ||
| Endoplasmic reticulum stress and type 2 diabetes | Q26864238 | ||
| Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus | Q26864403 | ||
| edgeR: a Bioconductor package for differential expression analysis of digital gene expression data | Q27860819 | ||
| Mutational spectrum of the WFS1 gene in Wolfram syndrome, nonsyndromic hearing impairment, diabetes mellitus, and psychiatric disease | Q28205046 | ||
| WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells | Q28508342 | ||
| STAR: ultrafast universal RNA-seq aligner | Q29615052 | ||
| limma powers differential expression analyses for RNA-sequencing and microarray studies | Q29617988 | ||
| Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes | Q29619192 | ||
| The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. | Q33300966 | ||
| Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death | Q33912118 | ||
| RSeQC: quality control of RNA-seq experiments | Q34284787 | ||
| featureCounts: an efficient general purpose program for assigning sequence reads to genomic features | Q34384848 | ||
| Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci | Q34518460 | ||
| Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity | Q34574951 | ||
| A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome | Q34709034 | ||
| Endoplasmic reticulum stress and the development of diabetes: a review | Q35022174 | ||
| Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses | Q36002387 | ||
| Insulin demand regulates β cell number via the unfolded protein response | Q36165645 | ||
| Mechanisms of beta-cell death in type 2 diabetes. | Q36321520 | ||
| Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities | Q36321572 | ||
| Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner | Q36796639 | ||
| RNA-sequencing of WFS1-deficient pancreatic islets | Q36797423 | ||
| The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes | Q36861041 | ||
| Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
| Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation | Q37251162 | ||
| Pancreatic β cell identity requires continual repression of non-β cell programs. | Q37545009 | ||
| Calcium efflux from the endoplasmic reticulum leads to β-cell death | Q37594059 | ||
| Wolfram syndrome iPS cells: the first human cell model of endoplasmic reticulum disease | Q37597029 | ||
| β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome | Q37597032 | ||
| ER stress in pancreatic beta cells: the thin red line between adaptation and failure | Q37697386 | ||
| Endoplasmic reticulum stress and pancreatic β-cell death | Q37860493 | ||
| Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes | Q38040992 | ||
| Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation | Q38420037 | ||
| Salmon provides fast and bias-aware quantification of transcript expression | Q38926825 | ||
| Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes | Q40176269 | ||
| Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. | Q40236795 | ||
| Involvement of PDX-1 in activation of human insulin gene transcription | Q40320021 | ||
| WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells | Q40367285 | ||
| Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion | Q40871524 | ||
| Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy | Q41054906 | ||
| Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls. | Q41480990 | ||
| Common variants in WFS1 confer risk of type 2 diabetes | Q41852502 | ||
| Control of pancreatic β cell regeneration by glucose metabolism. | Q42486224 | ||
| Species identity of insect cell lines | Q42996790 | ||
| Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2. | Q44212502 | ||
| Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion | Q44824148 | ||
| Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis | Q46744627 | ||
| Genotypic classification of patients with Wolfram syndrome: insights into the natural history of the disease and correlation with phenotype | Q50357570 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| limma | Q112236343 | ||
| P921 | main subject | Wolfram syndrome | Q1153641 |
| Wolfram syndrome 1 | Q28024764 | ||
| P577 | publication date | 2020-02-14 | |
| P1433 | published in | Laboratory Investigation | Q6467260 |
| P1476 | title | Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival |
| Q94521569 | A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome | cites work | P2860 |
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