Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans

scientific article published on 18 February 2020

Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/JN/NXAA024
P932PMC publication ID7398787
P698PubMed publication ID32069356

P50authorLisette de GrootQ28958459
Marlou L. DirksQ51283512
Luc J.C. van LoonQ57090847
Benjamin T. WallQ88526958
Joan M.G. SendenQ124943226
P2093author name stringAndrew M Holwerda
Nicholas A Burd
Tyler A Churchward-Venne
René Koopman
Stefan H M Gorissen
Bart Pennings
Lex B Verdijk
Bart B L Groen
Jorn Trommelen
Peter T Res
Imre W K Kouw
Astrid M H Horstman
Cas J Fuchs
Jan M J M Steijns
P2860cites workGreater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly menQ28112004
Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exerciseQ28262423
Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adultsQ30497114
The digestion rate of protein is an independent regulating factor of postprandial protein retentionQ31833571
An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscleQ33840291
Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signalingQ34032001
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscleQ34376051
Slow and fast dietary proteins differently modulate postprandial protein accretionQ34450151
Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men.Q34635710
Substantial Differences between Organ and Muscle Specific Tracer Incorporation Rates in a Lactating Dairy CowQ34797764
Aging Is Accompanied by a Blunted Muscle Protein Synthetic Response to Protein IngestionQ35831958
Post-Prandial Protein Handling: You Are What You Just AteQ35838058
Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exerciseQ36454435
Ingestion of Wheat Protein Increases In Vivo Muscle Protein Synthesis Rates in Healthy Older Men in a Randomized Trial.Q39578736
Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men.Q41874315
Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men.Q42462834
The production of intrinsically labeled milk protein provides a functional tool for human nutrition research.Q43275073
The rate of protein digestion affects protein gain differently during aging in humansQ44383090
Absorption kinetics are a key factor regulating postprandial protein metabolism in response to qualitative and quantitative variations in protein intakeQ44409041
Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exerciseQ44428271
Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men.Q45933584
Disuse impairs the muscle protein synthetic response to protein ingestion in healthy men.Q46110410
Co-ingesting milk fat with micellar casein does not affect postprandial protein handling in healthy older men.Q47602697
Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled TrialQ47691486
Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact proteinQ47713830
Pre-sleep dietary protein-derived amino acids are incorporated in myofibrillar protein during post-exercise overnight recovery.Q47728120
Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning.Q47801685
Resistance Exercise Augments Postprandial Overnight Muscle Protein Synthesis RatesQ47814861
Physical Activity Performed in the Evening Increases the Overnight Muscle Protein Synthetic Response to Presleep Protein Ingestion in Older Men.Q47848429
Intragastric protein administration stimulates overnight muscle protein synthesis in elderly men.Q48111127
Habituation to low or high protein intake does not modulate basal or postprandial muscle protein synthesis rates: a randomized trialQ48187923
Protein Ingestion before Sleep Improves Postexercise Overnight RecoveryQ48258808
Differences in postprandial protein handling after beef compared with milk ingestion during postexercise recovery: a randomized controlled trial.Q50437357
Postprandial Protein Handling Is Not Impaired in Type 2 Diabetes Patients When Compared With Normoglycemic Controls.Q50548654
A single session of neuromuscular electrical stimulation does not augment postprandial muscle protein accretion.Q51283475
Increasing Insulin Availability Does Not Augment Postprandial Muscle Protein Synthesis Rates in Healthy Young and Older Men.Q51389766
Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men.Q51422582
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men.Q51597144
Exercising before protein intake allows for greater use of dietary protein-derived amino acids for de novo muscle protein synthesis in both young and elderly men.Q51636244
Muscle Protein Synthesis Measured by Stable Isotope Techniques in Man: The Effects of Feeding and FastingQ51649100
Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion.Q53808869
Sodium nitrate co-ingestion with protein does not augment postprandial muscle protein synthesis rates in older, type 2 diabetes patients.Q54150576
Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men.Q55051183
Ingestion of Casein in a Milk Matrix Modulates Dietary Protein Digestion and Absorption Kinetics but Does Not Modulate Postprandial Muscle Protein Synthesis in Older MenQ57580312
Carbohydrate Coingestion Delays Dietary Protein Digestion and Absorption but Does Not Modulate Postprandial Muscle Protein AccretionQ57580325
The production of intrinsically labeled milk and meat protein is feasible and provides functional tools for human nutrition researchQ57580373
Dietary Protein Digestion and Absorption Rates and the Subsequent Postprandial Muscle Protein Synthetic Response Do Not Differ between Young and Elderly MenQ57580377
Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older MenQ61800311
Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in manQ70170063
Acute postprandial changes in leucine metabolism as assessed with an intrinsically labeled milk proteinQ71978095
Splanchnic and whole-body leucine kinetics in young and elderly menQ73044381
Postprandial kinetics of dietary amino acids are the main determinant of their metabolism after soy or milk protein ingestion in humansQ73350388
Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extractionQ78252564
Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humansQ80471118
Maximizing Post-exercise Anabolism: The Case for Relative Protein IntakesQ90267528
Myofibrillar and Mitochondrial Protein Synthesis Rates Do Not Differ in Young Men Following the Ingestion of Carbohydrate with Milk Protein, Whey, or Micellar Casein after Concurrent Resistance- and Endurance-Type ExerciseQ91277420
Postexercise cooling impairs muscle protein synthesis rates in recreational athletesQ91590225
The Muscle Protein Synthetic Response to Whey Protein Ingestion Is Greater in Middle-Aged Women Compared With MenQ93035711
Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trialQ93098425
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P577publication date2020-02-18
P1433published inJournal of NutritionQ3186931
P1476titleProtein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans

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cites work (P2860)
Q98190318A period of 10 weeks of increased protein consumption does not alter faecal microbiota or volatile metabolites in healthy older men: a randomised controlled trial
Q104746479Assessing the whole-body protein synthetic response to feeding in vivo in human subjects
Q100532883Nutrient-dense protein as a primary dietary strategy in healthy ageing: Please sir, may we have more?

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