Transplantation of iPSC-TM stimulates division of trabecular meshwork cells in human eyes

scientific article published on 19 February 2020

Transplantation of iPSC-TM stimulates division of trabecular meshwork cells in human eyes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-020-59941-0
P932PMC publication ID7031365
P698PubMed publication ID32076077

P50authorMarkus H KuehnQ46253326
Lin ChengQ47169145
P2093author name stringWei Zhu
Todd E Scheetz
Cheyanne R Godwin
P2860cites workTopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusionsQ21999527
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationQ24627354
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Factors influencing in vivo trabecular cell replication as determined by 3H-thymidine labelling; an autoradiographic study in catsQ31096048
Constitutive secretion of chemokines by cultured human trabecular meshwork cellsQ33559245
Genetic background drives transcriptional variation in human induced pluripotent stem cellsQ33716774
Ki-67 and other proliferation markers useful for immunohistological diagnostic and prognostic evaluations in human malignanciesQ33733805
Stimulation of cell division by argon and Nd:YAG laser trabeculoplasty in cynomolgus monkeysQ34416855
Induction of trabecular meshwork cells from induced pluripotent stem cellsQ34473805
Trabecular meshwork cellularity. Differences between fellow eyesQ34710335
Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye.Q35629172
The intrinsic stiffness of human trabecular meshwork cells increases with senescence.Q36021030
Identification of adult stem cells in Schwalbe's line region of the primate eye.Q36072940
Changes in aqueous humor dynamics with age and glaucomaQ36140991
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of HeterogeneityQ36233059
Trabecular repopulation by anterior trabecular meshwork cells after laser trabeculoplastyQ36416921
FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsivenessQ36742066
Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo.Q37040712
Trabecular meshwork stiffness in glaucomaQ38905864
Neuroinflammation in glaucoma: A new opportunity.Q39153080
Metabolic Vulnerability in the Neurodegenerative Disease GlaucomaQ39251141
Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal DegenerationQ41643417
Induced pluripotent stem cells restore function in a human cell loss model of open-angle glaucomaQ41862093
Histologic findings in pigment dispersion syndrome and pigmentary glaucomaQ42683834
Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma.Q47923294
Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal DegenerationQ48594838
Age-related depletion of the cell population in the human trabecular meshwork.Q52428580
Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.Q53079713
Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)Q53956831
Histopathology of 150 trabeculectomy specimens in glaucomaQ66863113
Human trabecular meshwork organ culture. A new methodQ69024646
Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normalsQ70571024
Age-related changes in trabecular meshwork cellularityQ70975028
Aqueous humor dynamics in the aging human eyeQ77370299
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)2905
P577publication date2020-02-19
P1433published inScientific ReportsQ2261792
P1476titleTransplantation of iPSC-TM stimulates division of trabecular meshwork cells in human eyes
P478volume10

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