Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye.

scientific article published on May 2015

Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1167/IOVS.14-15891
P932PMC publication ID4439132
P698PubMed publication ID26024091

P50authorVal C. SheffieldQ61268600
P2093author name stringJean Sévigny
Xiulan Zhang
B'Ann T Gabelt
Paul L Kaufman
Alan M Laties
Claire H Mitchell
Wennan Lu
Elaine C Johnson
John C Morrison
Gulab S Zode
HuiLing Hu
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Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma ModelQ33738662
Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strainQ34049695
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflowQ34426403
Visual field progression outcomes in glaucoma subtypesQ85046575
NTPDase1 governs P2X7-dependent functions in murine macrophagesQ34610192
The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significanceQ34769236
A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucomaQ35082369
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Mechanisms of Release of Nucleotides and Integration of Their Action as P2X- and P2Y-Receptor Activating MoleculesQ35538706
Effect of treatment on the rate of visual field change in the ocular hypertension treatment study observation groupQ35929958
Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucomaQ36030094
Enhancing trabecular outflow by disrupting the actin cytoskeleton, increasing uveoscleral outflow with prostaglandins, and understanding the pathophysiology of presbyopia interrogating Mother Nature: asking why, asking how, recognizing the signs, foQ36403804
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Degradation of extracellular ATP by the retinal pigment epithelium.Q40429839
Elevated pressure triggers a physiological release of ATP from the retina: Possible role for pannexin hemichannels.Q42044747
Neurochemical correlates of cortical plasticity after unilateral elevated intraocular pressure in a primate model of glaucomaQ44453123
Immunocytochemical localization of NTPDases1 and 2 in the neural retina of mouse and zebrafishQ46178917
Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondriaQ46311555
Purinergic receptor activation inhibits osmotic glial cell swelling in the diabetic rat retinaQ46440485
Stimulation of P2X7 receptors elevates Ca2+ and kills retinal ganglion cellsQ46508393
Glycosylation is essential for functional expression of a human brain ecto-apyrase.Q48292386
Assignment of ecto-nucleoside triphosphate diphosphohydrolase-1/cd39 expression to microglia and vasculature of the brainQ49144649
Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulationQ50336029
Long-term follow-up in preperimetric open-angle glaucoma: progression rates and associated factorsQ50456294
Acute retinal ganglion cell injury caused by intraocular pressure spikes is mediated by endogenous extracellular ATPQ61905661
The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration.The AGIS InvestigatorsQ73055302
A rat model of chronic pressure-induced optic nerve damageQ73202589
Structural elements and limited proteolysis of CD39 influence ATP diphosphohydrolase activityQ74462843
Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulationQ79807526
Acute increase of intraocular pressure releases ATP into the anterior chamberQ81151629
Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptorsQ83629988
P4510describes a project that usesImageQuantQ112270642
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)3075-3083
P577publication date2015-05-01
P1433published inInvestigative Ophthalmology Visual ScienceQ6060707
P1476titleRat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye.
P478volume56

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