Toxoplasma gondii ROP16I Deletion: The Exacerbated Impact on Adverse Pregnant Outcomes in Mice

scientific article published on 01 January 2019

Toxoplasma gondii ROP16I Deletion: The Exacerbated Impact on Adverse Pregnant Outcomes in Mice is …
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scholarly articleQ13442814

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P356DOI10.3389/FMICB.2019.03151
P932PMC publication ID7005636
P698PubMed publication ID32082272

P2093author name stringWei Wang
Wen Cui
Qingli Luo
Cong Wang
Jilong Shen
Tian Xing
P2860cites workPotential role of macrophages as immunoregulators of pregnancyQ24801262
ToxoplasmosisQ30080013
Globalization and the population structure of Toxoplasma gondiiQ30355588
A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.Q33591077
Uterine Natural Killer Cells: Functional Distinctions and Influence on Pregnancy in Humans and MiceQ33594882
The Effect of TGF-β on Treg Cells in Adverse Pregnancy Outcome upon Toxoplasma gondii InfectionQ33729309
Maternal decidual macrophages inhibit NK cell killing of invasive cytotrophoblasts during human pregnancyQ33806368
Genotypic characterization of Toxoplasma gondii strains associated with human toxoplasmosis in Spain: direct analysis from clinical samplesQ33972010
Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth controlQ34023014
Lytic cycle of Toxoplasma gondiiQ34023676
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Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.Q34501481
Genotypes and mouse virulence of Toxoplasma gondii isolates from animals and humans in ChinaQ34545122
Toxoplasma Chinese 1 Strain of WH3Δrop16I/III/gra15II Genetic Background Contributes to Abnormal Pregnant Outcomes in Murine Model.Q55134596
Type I ROP16 regulates retinal inflammatory responses during ocular toxoplasmosisQ64063550
Differential regulation and function of the Fas/Fas ligand system in human trophoblast cellsQ74137173
Cytokine secretion patterns of NK cells and macrophages in early human pregnancy decidua and blood: implications for suppressor macrophages in deciduaQ75359304
p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infectionQ81546534
Decidual macrophage M1 polarization contributes to adverse pregnancy induced by Toxoplasma gondii PRU strain infectionQ91127612
M1/M2 macrophage polarity in normal and complicated pregnancyQ34562992
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Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.Q35090382
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Tissue barriers of the human placenta to infection with Toxoplasma gondiiQ35665488
CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brainQ35848508
HIV-Associated Central Nervous System Disease in Patients Admitted at the Douala General Hospital between 2004 and 2009: A Retrospective StudyQ36692405
Cellular and molecular physiopathology of congenital toxoplasmosis: the dual role of IFN-gammaQ36980854
Polymorphic secreted kinases are key virulence factors in toxoplasmosisQ37105671
A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.Q37194952
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Do the placental barrier, parasite genotype and Toll-like receptor polymorphisms contribute to the course of primary infection with various Toxoplasma gondii genotypes in pregnant women?Q37717766
Toxoplasmosis in HIV/AIDS: a living legacy.Q37767684
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Geographical patterns of Toxoplasma gondii genetic diversity revealed by multilocus PCR-RFLP genotypingQ38183236
Toxoplasma Effectors Targeting Host Signaling and TranscriptionQ38731005
Decidual Macrophage Functional Polarization during Abnormal Pregnancy due to Toxoplasma gondii: Role for LILRB4.Q40061446
Maternal serum of women with pre-eclampsia reduces trophoblast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosisQ40652949
IL-10 regulate decidual Tregs apoptosis contributing to the abnormal pregnancy with Toxoplasma gondii infectionQ40921048
Toxoplasma gondii isolate with genotype Chinese 1 triggers trophoblast apoptosis through oxidative stress and mitochondrial dysfunction in miceQ41285594
Clinical features and outcomes in patients with disseminated toxoplasmosis admitted to intensive care: a multicenter studyQ42272908
Molecular genotyping of Toxoplasma gondii from Central and South America revealed high diversity within and between populationsQ43509920
Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic womenQ43705726
Trophoblast apoptosis through polarization of macrophages induced by Chinese Toxoplasma gondii isolates with different virulence in pregnant miceQ43749810
The Treg/Th17 imbalance in Toxoplasma gondii-infected pregnant miceQ44696443
Adoptive transfer of Treg cells counters adverse effects of Toxoplasma gondii infection on pregnancyQ48866719
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P921main subjectToxoplasma gondiiQ131003
P304page(s)3151
P577publication date2019-01-01
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleToxoplasma gondii ROP16I Deletion: The Exacerbated Impact on Adverse Pregnant Outcomes in Mice
P478volume10

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