The impact of leadered and leaderless gene structures on translation efficiency, transcript stability, and predicted transcription rates in Mycobacterium smegmatis

scientific article published on 24 February 2020

The impact of leadered and leaderless gene structures on translation efficiency, transcript stability, and predicted transcription rates in Mycobacterium smegmatis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.00746-19
P932PMC publication ID7148126
P698PubMed publication ID32094162

P2093author name stringLouis A Roberts
Scarlet S Shell
Tien G Nguyen
Diego A Vargas-Blanco
P2860cites workGenomic Characterization of Mycobacteriophage Giles: Evidence for Phage Acquisition of Host DNA by Illegitimate RecombinationQ22061802
RNA secondary structure prediction by centroids in a Boltzmann weighted ensembleQ24537445
Sfold web server for statistical folding and rational design of nucleic acidsQ24562042
A trans-acting RNA as a control switch in Escherichia coli: DsrA modulates function by forming alternative structuresQ24652762
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressorQ24802513
Structure of Escherichia coli Hfq bound to polyriboadenylate RNAQ27658064
A NusE:NusG complex links transcription and translationQ27660765
The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sitesQ29618224
Messenger Ribonucleic Acid Synthesis and Degradation in Escherichia coli During Inhibition of TranslationQ33788359
The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5'-untranslated part of mRNA.Q33801601
The initiation codon affects ribosome binding and translational efficiency in Escherichia coli of cI mRNA with or without the 5' untranslated leaderQ33995578
Leaderless mRNAs bind 70S ribosomes more strongly than 30S ribosomal subunits in Escherichia coliQ34320201
Induced mRNA stability in Bacillus subtilisQ34589447
Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosisQ35051702
The highly efficient translation initiation region from the Escherichia coli rpsA gene lacks a shine-dalgarno elementQ35075361
Genome-wide study of mRNA degradation and transcript elongation in Escherichia coliQ35094002
Sigma factors and global gene regulation in Mycobacterium tuberculosisQ35648489
Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymeraseQ35808746
Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.Q35832097
Effect of translational signals on mRNA decay in Bacillus subtilisQ35921943
Roles of a ribosome-binding site and mRNA secondary structure in differential expression of Shiga toxin genesQ35966752
5'-Terminal AUGs in Escherichia coli mRNAs with Shine-Dalgarno Sequences: Identification and Analysis of Their Roles in Non-Canonical Translation InitiationQ36088807
Structure and function of a bacterial mRNA stabilizer: analysis of the 5' untranslated region of ompA mRNAQ36149958
The ompA 5' untranslated RNA segment functions in Escherichia coli as a growth-rate-regulated mRNA stabilizer whose activity is unrelated to translational efficiencyQ36255399
Degradation of pufLMX mRNA in Rhodobacter capsulatus is initiated by nonrandom endonucleolytic cleavageQ36255745
Global analysis of mRNA stability in Mycobacterium tuberculosisQ36668941
A modular strategy for engineering orthogonal chimeric RNA transcription regulatorsQ37122019
Codon influence on protein expression in E. coli correlates with mRNA levelsQ37319891
Determination of the optimal aligned spacing between the Shine-Dalgarno sequence and the translation initiation codon of Escherichia coli mRNAsQ37587211
Dual role of transcription and transcript stability in the regulation of gene expression in Escherichia coli cells cultured on glucose at different growth rates.Q37606927
Messenger RNA Turnover Processes in Escherichia coli, Bacillus subtilis, and Emerging Studies in Staphylococcus aureusQ37638237
Mycobacterial RNA polymerase requires a U-tract at intrinsic terminators and is aided by NusG at suboptimal terminatorsQ37714062
The DNA binding protein H-NS binds to and alters the stability of RNA in vitro and in vivoQ38341060
RNase E enzymes from rhodobacter capsulatus and Escherichia coli differ in context- and sequence-dependent in vivo cleavage within the polycistronic puf mRNA.Q39498234
DksA guards elongating RNA polymerase against ribosome-stalling-induced arrestQ39688530
Coincident Hfq binding and RNase E cleavage sites on mRNA and small regulatory RNAsQ39784092
An efficient Shine-Dalgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coliQ39931015
Transcription through the roadblocks: the role of RNA polymerase cooperationQ39958725
Defining a temporal order of genetic requirements for development of mycobacterial biofilmsQ40167251
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platformQ40343712
Selective stimulation of translation of leaderless mRNA by initiation factor 2: evolutionary implications for translationQ40392383
Lack of a 5' non-coding region in Tn1721encodedtetRmRNA is associated with a low efficiency of translation and a short half-life inEscherichia coilQ40506498
Absolute Proteome Composition and Dynamics during Dormancy and Resuscitation of Mycobacterium tuberculosisQ40816049
Translation initiation with 70S ribosomes: an alternative pathway for leaderless mRNAsQ41023136
Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymeraseQ41727425
Taking phage integration to the next level as a genetic tool for mycobacteriaQ41914183
Continuous control of the flow in biochemical pathways through 5' untranslated region sequence modifications in mRNA expressed from the broad-host-range promoter PmQ42120473
Cooperation between translating ribosomes and RNA polymerase in transcription elongationQ42159573
Ribosomes inhibit an RNase E cleavage which induces the decay of the rpsO mRNA of Escherichia coli.Q42652001
Stem-Loop Structures within mRNA Coding Sequences Activate Translation Initiation and Mediate Control by Small Regulatory RNAsQ42691111
mRNA stabilization by the ompA 5' untranslated region: two protective elements hinder distinct pathways for mRNA degradation.Q43206208
Translation initiation factor 3 antagonizes authentic start codon selection on leaderless mRNAsQ44176895
Transcription-translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits.Q45986934
Rationally designed families of orthogonal RNA regulators of translationQ46091999
The stability of mRNA from the gsiB gene of Bacillus subtilis is dependent on the presence of a strong ribosome binding site.Q47822247
The relationship between translational control and mRNA degradation for the Escherichia coli threonyl-tRNA synthetase geneQ49203292
Unstructured 5'-tails act through ribosome standby to override inhibitory structure at ribosome binding sitesQ50113583
Alternate paradigm for intrinsic transcription termination in eubacteria.Q52055327
Translation initiation in Escherichia coli: sequences within the ribosome-binding siteQ52231762
sigA is an essential gene in Mycobacterium smegmatis.Q52531658
STAB-SD: a Shine-Dalgarno sequence in the 5' untranslated region is a determinant of mRNA stability.Q52549133
The functional half-life of an mRNA depends on the ribosome spacing in an early coding region.Q54369921
Evidence for the translation initiation of leaderless mRNAs by the intact 70 S ribosome without its dissociation into subunits in eubacteria.Q54514033
Effects of ribosomal proteins S1, S2 and the DeaD/CsdA DEAD-box helicase on translation of leaderless and canonical mRNAs in Escherichia coli.Q54543626
Effect of the pufQ-pufB intercistronic region on puf mRNA stability in Rhodobacter capsulatus.Q54587494
Global Regulation by CsrA and Its RNA Antagonists.Q55112803
Poly(A) polymerase is required for RyhB sRNA stability and function inQ58702556
Defining the Transcriptional and Post-transcriptional Landscapes of in Aerobic Growth and HypoxiaQ64118325
A 5'-terminal stem-loop structure can stabilize mRNA in Escherichia coliQ67531014
The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segmentsQ68883019
Visualization of Bacterial Genes in ActionQ69913697
The aprE leader is a determinant of extreme mRNA stability in Bacillus subtilisQ73256442
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAsQ73714744
A 5' stem-loop and ribosome binding but not translation are important for the stability of Bacillus subtilis aprE leader mRNAQ74261565
Temperature-dependent translation of leaderless and canonical mRNAs in Escherichia coliQ74333532
An AUG initiation codon, not codon-anticodon complementarity, is required for the translation of unleadered mRNA in Escherichia coliQ74422702
Accessibility of the Shine-Dalgarno Sequence Dictates N-Terminal Codon Bias in E. coliQ89043266
mRNA Degradation Rates Are Coupled to Metabolic Status in Mycobacterium smegmatisQ91563864
Obstacles to Scanning by RNase E Govern Bacterial mRNA Lifetimes by Hindering Access to Distal Cleavage SitesQ92244692
P921main subjectMycobacterium smegmatisQ606230
P577publication date2020-02-24
P1433published inJournal of BacteriologyQ478419
P1476titleThe impact of leadered and leaderless gene structures on translation efficiency, transcript stability, and predicted transcription rates in Mycobacterium smegmatis

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