| P50 | author | Qiang Shao | Q47696131 |
| P2093 | author name string | Rong Chen | |
| | Li Ma | |
| | Wei Zhang | |
| | Jian Xu | |
| | Jian-Fu Chen | |
| | Mei Yang | |
| | Yang Chai | |
| | Zhen Zhao | |
| | Zhipeng Lu | |
| P2860 | cites work | Genome engineering using the CRISPR-Cas9 system | Q22122027 |
| | Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure | Q24004552 |
| | Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephaly | Q24299324 |
| | Rab39a interacts with phosphatidylinositol 3-kinase and negatively regulates autophagy induced by lipopolysaccharide stimulation in macrophages | Q24314423 |
| | AKT/PKB signaling: navigating downstream | Q24657857 |
| | The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia. | Q26766054 |
| | Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism | Q26782948 |
| | Molecular identity of human outer radial glia during cortical development | Q27321802 |
| | Induction of Expansion and Folding in Human Cerebral Organoids | Q28114555 |
| | Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders | Q28279421 |
| | Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia | Q28595116 |
| | Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development | Q28690751 |
| | FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders | Q28973611 |
| | Cerebral organoids model human brain development and microcephaly | Q28973619 |
| | A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy | Q29465530 |
| | Behavioural phenotyping assays for mouse models of autism | Q29618414 |
| | Animal models of neuropsychiatric disorders | Q29619899 |
| | The RAB39B p.G192R mutation causes X-linked dominant Parkinson's disease | Q30665368 |
| | Longitudinal changes in cortical thickness in autism and typical development | Q33654230 |
| | Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests | Q33711537 |
| | Mutations in RAB39B in individuals with intellectual disability, autism spectrum disorder, and macrocephaly | Q47148977 |
| | X-linked Parkinsonism with Intellectual Disability caused by novel mutations and somatic mosaicism in RAB39B gene. | Q47887711 |
| | Abnormal mTOR Activation in Autism. | Q50301111 |
| | A role for intermediate radial glia in the tangential expansion of the mammalian cerebral cortex. | Q51894316 |
| | Rotorod sensorimotor learning in cerebellar mutant mice. | Q52207662 |
| | The ASD Living Biology: from cell proliferation to clinical phenotype | Q89207617 |
| | Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons | Q90929165 |
| | Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution | Q91421377 |
| | Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors | Q92733484 |
| | Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits | Q33756508 |
| | Patches of disorganization in the neocortex of children with autism | Q34040334 |
| | Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages | Q34211584 |
| | A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution | Q34289050 |
| | Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology | Q34657526 |
| | The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition. | Q35247088 |
| | Changes in cell-cycle kinetics during the development and evolution of primate neocortex | Q35801965 |
| | Early brain overgrowth in autism associated with an increase in cortical surface area before age 2 years | Q35859835 |
| | Increased Surface Area, but not Cortical Thickness, in a Subset of Young Boys With Autism Spectrum Disorder. | Q36950297 |
| | Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorder | Q37124525 |
| | Neural stem and progenitor cells in cortical development | Q37169442 |
| | Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex | Q37395157 |
| | Altered proliferation and networks in neural cells derived from idiopathic autistic individuals | Q37562213 |
| | Regulation of cerebral cortex size and folding by expansion of basal progenitors | Q37587995 |
| | Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism | Q37716254 |
| | Combined Targeting of mTOR and Akt Using Rapamycin and MK-2206 in The Treatment of Tuberous Sclerosis Complex | Q37726384 |
| | Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder? | Q37729341 |
| | Autism genetics: searching for specificity and convergence | Q38031004 |
| | Genetics studies indicate that neural induction and early neuronal maturation are disturbed in autism | Q38283524 |
| | MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo | Q38431323 |
| | Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling | Q38442957 |
| | Head circumference and brain size in autism spectrum disorder: A systematic review and meta-analysis | Q38604456 |
| | Proliferation and Differentiation Deficits are a Major Convergence Point for Neurodevelopmental Disorders | Q38794752 |
| | Early brain development in infants at high risk for autism spectrum disorder | Q38959207 |
| | Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks | Q39279039 |
| | Synaptic dysregulation in a human iPS cell model of mental disorders | Q41534293 |
| | Somatic activation of AKT3 causes hemispheric developmental brain malformations | Q41773363 |
| | A new subtype of progenitor cell in the mouse embryonic neocortex | Q41917661 |
| | Toward a conceptual framework for early brain and behavior development in autism | Q42367573 |
| | Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. | Q42459454 |
| | Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors. | Q42488382 |
| | Cell diversity and network dynamics in photosensitive human brain organoids. | Q42615577 |
| | Evidence of brain overgrowth in the first year of life in autism | Q44996531 |
| | Behavioral Phenotyping Assays for Genetic Mouse Models of Neurodevelopmental, Neurodegenerative, and Psychiatric Disorders. | Q45975784 |
| | The use of brain organoids to investigate neural development and disease | Q46137846 |
| | The PI3K Pathway in Human Disease | Q46546002 |
| | Germline Chd8 haploinsufficiency alters brain development in mouse. | Q46718483 |
| | Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex | Q46852287 |
| | Neuron number and size in prefrontal cortex of children with autism | Q46915992 |
| P433 | issue | 7-8 | |
| P921 | main subject | organoid | Q11293125 |
| P304 | page(s) | 580-597 | |
| P577 | publication date | 2020-02-27 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes | |
| P478 | volume | 34 | |