scholarly article | Q13442814 |
P819 | ADS bibcode | 2019NatCo..10.2612Z |
P356 | DOI | 10.1038/S41467-019-10497-2 |
P932 | PMC publication ID | 6565620 |
P698 | PubMed publication ID | 31197141 |
P50 | author | Qiang Shao | Q47696131 |
Aimin Liu | Q57569813 | ||
Bruce E Herring | Q89025870 | ||
Yanhong Shi | Q90740449 | ||
John L Collar | Q92733481 | ||
P2093 | author name string | Wei Zhang | |
Jian Xu | |||
Jian-Fu Chen | |||
Mei Yang | |||
Shilpa Buch | |||
Hui Lu | |||
Zhen Zhao | |||
Zhipeng Lu | |||
Ming-Lei Guo | |||
Stephanie Herrlinger | |||
Si-Lu Yang | |||
Edgar Fierro | |||
P2860 | cites work | Genome engineering using the CRISPR-Cas9 system | Q22122027 |
Evolution of the brain and intelligence | Q22337311 | ||
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure | Q24004552 | ||
Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations | Q24296941 | ||
Cep164, a novel centriole appendage protein required for primary cilium formation | Q24298367 | ||
Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture | Q24301645 | ||
WDR62 is associated with the spindle pole and is mutated in human microcephaly | Q24301673 | ||
The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles | Q24556578 | ||
Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits | Q27919676 | ||
Cilium assembly and disassembly | Q28067455 | ||
Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication | Q28115110 | ||
CDK5RAP2 regulates centriole engagement and cohesion in mice | Q28505755 | ||
MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway | Q28506694 | ||
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella | Q28593253 | ||
Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia | Q28595116 | ||
CPAP promotes timely cilium disassembly to maintain neural progenitor pool | Q28973602 | ||
Cerebral organoids model human brain development and microcephaly | Q28973619 | ||
The primary cilium: a signalling centre during vertebrate development | Q29547197 | ||
The primary cilium as the cell's antenna: signaling at a sensory organelle | Q29615165 | ||
Centrioles, centrosomes, and cilia in health and disease | Q29615173 | ||
Neurogenic radial glia in the outer subventricular zone of human neocortex | Q29616182 | ||
WD40 proteins propel cellular networks. | Q30156873 | ||
Spindle poisons and cell fate: a tale of two pathways. | Q30431071 | ||
Primary microcephaly: do all roads lead to Rome? | Q33629131 | ||
Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth. | Q33906455 | ||
Developmental genetics of vertebrate glial-cell specification. | Q34149150 | ||
Molecular genetic determinants of human brain size | Q34529143 | ||
A genomic toolkit to investigate kinesin and myosin motor function in cells | Q34589246 | ||
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry | Q34796294 | ||
What disorders of cortical development tell us about the cortex: one plus one does not always make two | Q35115582 | ||
G1 phase regulation, area-specific cell cycle control, and cytoarchitectonics in the primate cortex | Q35839746 | ||
Cdk5rap2 exposes the centrosomal root of microcephaly syndromes | Q36021561 | ||
Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly | Q37304298 | ||
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex | Q37395157 | ||
The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation. | Q37398735 | ||
Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly | Q37685924 | ||
The primary cilium as a cellular receiver: organizing ciliary GPCR signaling | Q38754528 | ||
Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors | Q39537369 | ||
A new subtype of progenitor cell in the mouse embryonic neocortex | Q41917661 | ||
PLK1-mediated phosphorylation of WDR62/MCPH2 ensures proper mitotic spindle orientation | Q41918159 | ||
Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate | Q41921410 | ||
The Microcephaly-Associated Protein Wdr62/CG7337 Is Required to Maintain Centrosome Asymmetry in Drosophila Neuroblasts | Q41926666 | ||
Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size | Q41930126 | ||
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. | Q42459454 | ||
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling | Q42470977 | ||
Cell diversity and network dynamics in photosensitive human brain organoids. | Q42615577 | ||
Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development. | Q47595186 | ||
Mitotic catastrophe: a mechanism for avoiding genomic instability. | Q52610466 | ||
Do cilia put brakes on the cell cycle? | Q83771992 | ||
Microtubule-depolymerizing kinesins | Q87130000 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | organoid | Q11293125 |
microcephaly | Q431643 | ||
P304 | page(s) | 2612 | |
P577 | publication date | 2019-06-13 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors | |
P478 | volume | 10 |
Q97516713 | Application of Fused Organoid Models to Study Human Brain Development and Neural Disorders |
Q96128071 | Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease |
Q89960154 | Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes |
Q84957742 | Cortical Malformations: Lessons in Human Brain Development |
Q90064979 | FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas |
Q95840623 | Human Brain Organoids to Decode Mechanisms of Microcephaly |
Q102075330 | RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis |
Q96304780 | Urine Sample-Derived Cerebral Organoids Suitable for Studying Neurodevelopment and Pharmacological Responses |
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