The synaptic action of Degenerin/Epithelial sodium channels

scientific article published on 01 January 2018

The synaptic action of Degenerin/Epithelial sodium channels is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/19336950.2018.1495006
P932PMC publication ID6986788
P698PubMed publication ID30001175

P50authorYehuda Ben-ShaharQ89328631
Alexis S HillQ89994730
P2860cites workThe acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memoryQ24296641
Cloning and expression of a novel human brain Na+ channelQ24309379
A proton-gated cation channel involved in acid-sensingQ24329227
A role for ASIC3 in the modulation of high-intensity pain stimuliQ24531174
Calcium control of neurotransmitter releaseQ26269884
Development and plasticity of the Drosophila larval neuromuscular junctionQ26820443
Homeostatic plasticity at the Drosophila neuromuscular junctionQ26829672
Acid-sensing ion channels in pain and disease.Q26829975
Astrocytes Control Synapse Formation, Function, and EliminationQ27021730
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pHQ27648371
Pore architecture and ion sites in acid-sensing ion channels and P2X receptorsQ27656772
Molecular and functional characterization of acid-sensing ion channel (ASIC) 1bQ28205888
The molecular basis of CaMKII function in synaptic and behavioural memoryQ28216850
Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neuronsQ47679684
Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held SynapseQ47977487
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegansQ48085066
Rapid extracellular pH transients related to synaptic transmission in rat hippocampal slicesQ48171464
Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memoryQ48186778
The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degenerationQ48235681
Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning.Q48262735
Modulation of extracellular pH by glutamate and GABA in rat hippocampal slicesQ48594661
Acid-sensing ion channels promote the inflammation and migration of cultured rat microglia.Q51036965
Changes in paired-pulse facilitation suggest presynaptic involvement in long-term potentiation.Q52056856
ASIC1a polymorphism is associated with temporal lobe epilepsy.Q54365354
Structural and functional features of the intracellular amino terminus of DEG/ENaC ion channels.Q55034730
Caenorhabditis ElegansDegenerins and Vertebrate Enac Ion Channels Contain an Extracellular Domain Related to Venom NeurotoxinsQ57243217
Degenerin similaritiesQ59082956
The identification and suppression of inherited neurodegeneration in Caenorhabditis elegansQ59088240
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunitsQ28249570
Epithelial sodium channel related to proteins involved in neurodegenerationQ28262910
Expression cloning of an epithelial amiloride-sensitive Na+ channel. A new channel type with homologies to Caenorhabditis elegans degenerinsQ28262953
Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseasesQ28272095
Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neuronsQ28505408
Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout miceQ28512128
Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neuronsQ28582678
ASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95Q28592489
DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptorQ28740511
MAPK cascade signalling and synaptic plasticityQ29619955
Microglia: Dynamic Mediators of Synapse Development and Plasticity.Q30373424
Neurosensory mechanotransduction through acid-sensing ion channelsQ30423709
Restoring Acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responsesQ30486301
Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.Q30576923
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometryQ30580355
ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversionQ30831584
Calcium- and activity-dependent synaptic plasticityQ33680895
Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1aQ33697259
Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdalaQ33790161
Transient acidosis while retrieving a fear-related memory enhances its lability.Q33835038
The human ortholog of acid-sensing ion channel gene ASIC1a is associated with panic disorder and amygdala structure and functionQ33921974
Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity.Q33969340
High-Density Expression of Ca2+-Permeable ASIC1a Channels in NG2 Glia of Rat HippocampusQ34117406
Acid-sensing ion channels: trafficking and synaptic functionQ34320487
Genetic models of mechanotransduction: the nematode Caenorhabditis elegansQ34350636
The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegansQ34379814
unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotionQ34414566
More than a pore: ion channel signaling complexesQ34491609
Synaptic mitochondria in synaptic transmission and organization of vesicle pools in health and diseaseQ34689753
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.Q34711250
Drosophila DEG/ENaC pickpocket genes are expressed in the tracheal system, where they may be involved in liquid clearanceQ34763741
Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assayQ34801941
A synaptic DEG/ENaC ion channel mediates learning in C. elegans by facilitating dopamine signallingQ34889521
The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associateQ38757876
The Drosophila Postsynaptic DEG/ENaC Channel ppk29 Contributes to Excitatory NeurotransmissionQ38954580
Acid-sensing ion channels regulate spontaneous inhibitory activity in the hippocampus: possible implications for epilepsy.Q39632618
Rabbit retinal neurons and glia express a variety of ENaC/DEG subunitsQ40726518
Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic PlasticityQ41065922
Epithelial sodium channels: function, structure, and regulationQ41441322
Acid sensing ion channels regulate neuronal excitability by inhibiting BK potassium channelsQ41512163
Characterization of acid-sensing ion channel expression in oligodendrocyte-lineage cellsQ42099730
Targeting ASIC1a reduces innate fear and alters neuronal activity in the fear circuit.Q42627546
Existence and distinction of acid-evoked currents in rat astrocytesQ43022288
Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system.Q44267745
An amiloride-sensitive H+-gated Na+ channel in Caenorhabditis elegans body wall muscle cellsQ44978752
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signalsQ45174134
In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensationQ46089826
sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neuronsQ46413616
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous systemQ46906898
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines.Q35107378
ASIC-dependent LTP at multiple glutamatergic synapses in amygdala network is required for fear memory.Q35623326
Association between the ACCN1 gene and multiple sclerosis in Central East SardiniaQ35794487
Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC).Q35819038
ASIC1A in the bed nucleus of the stria terminalis mediates TMT-evoked freezing.Q35868897
Knockout of glial channel ACD-1 exacerbates sensory deficits in a C. elegans mutant by regulating calcium levels of sensory neuronsQ35951411
Mitochondria and neurotransmission: evacuating the synapseQ36213274
Sequence and transmembrane topology of MEC-4, an ion channel subunit required for mechanotransduction in Caenorhabditis elegansQ36236952
Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction.Q36238136
Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytesQ36436486
Acid-sensing ion channels interact with and inhibit BK K+ channelsQ36498545
Non-conducting functions of voltage-gated ion channelsQ36599917
The genetic architecture of degenerin/epithelial sodium channels in DrosophilaQ36642232
Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanismsQ36708087
Synaptic development: insights from DrosophilaQ36710476
A glial DEG/ENaC channel functions with neuronal channel DEG-1 to mediate specific sensory functions in C. elegansQ36891446
Seizure termination by acidosis depends on ASIC1aQ36908837
Two novel DEG/ENaC channel subunits expressed in glia are needed for nose-touch sensitivity in Caenorhabditis elegansQ37013669
Adenine nucleotide translocase, mitochondrial stress, and degenerative cell death.Q37067659
Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal deathQ37165215
Astrocytic Acid-Sensing Ion Channel 1a Contributes to the Development of Chronic EpileptogenesisQ37177095
A presynaptic ENaC channel drives homeostatic plasticityQ37201940
Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behaviorQ37262543
Multiple roles of calcium ions in the regulation of neurotransmitter releaseQ37279408
ENaC at the cutting edge: regulation of epithelial sodium channels by proteasesQ37343932
Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice.Q37575276
ASIC1a activation enhances inhibition in the basolateral amygdala and reduces anxiety.Q37603752
Transsynaptic channelosomes: non-conducting roles of ion channels in synapse formationQ37886522
Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potentialQ37967696
Insight into DEG/ENaC channel gating from genetics and structureQ38048561
The roles of protein kinases in learning and memoryQ38138433
Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter releaseQ38166028
How do astrocytes participate in neural plasticity?Q38287208
The mechanisms and functions of spontaneous neurotransmitter releaseQ38293976
ASICs and mammalian mechanoreceptor functionQ38295618
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P304page(s)262-275
P577publication date2018-01-01
P1433published inChannelsQ15764469
P1476titleThe synaptic action of Degenerin/Epithelial sodium channels
P478volume12