Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis

scientific article published on 10 September 2019

Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IJPDDR.2019.09.003
P932PMC publication ID6804374
P698PubMed publication ID31525614

P50authorPetr VolfQ42576321
P2093author name stringClaudio Meneses
Guy Caljon
Shaden Kamhawi
Louis Maes
Sarah Hendrickx
Lieselotte Van Bockstal
Jovana Sádlová
Hamide Aslan Suau
P2860cites workNIH Image to ImageJ: 25 years of image analysisQ23319322
Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasisQ28271849
Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncomplianceQ28285948
Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct MechanismsQ28554770
Epidemiology of visceral leishmaniasisQ33583456
Molecular aspects of parasite-vector and vector-host interactions in leishmaniasisQ34360809
The transmission of Leishmania infantum chagasi by the bite of the Lutzomyia longipalpis to two different vertebratesQ35800263
Leishmania manipulation of sand fly feeding behavior results in enhanced transmissionQ35865489
Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intracellular AmastigotesQ36001763
Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use.Q36524693
Phlebotomine sand flies and Leishmania parasites: friends or foes?Q36537320
Leishmania chitinase facilitates colonization of sand fly vectors and enhances transmission to mice.Q36691534
A new model of progressive visceral leishmaniasis in hamsters by natural transmission via bites of vector sand fliesQ36702606
Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from IndiaQ37615730
Pharmacovigilance of Miltefosine in Treatment of Visceral Leishmaniasis in Endemic Areas of Bihar, IndiaQ39373535
In vitro stimulation of metacyclogenesis in Leishmania braziliensis, L. donovani, L. major and L. mexicanaQ39621538
In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differencesQ41844113
Leishmania resistance to miltefosine associated with genetic markerQ42573934
Alteration of fatty acid and sterol metabolism in miltefosine-resistant Leishmania donovani promastigotes and consequences for drug-membrane interactionsQ42588360
Blocked stomodeal valve of the insect vector: similar mechanism of transmission in two trypanosomatid modelsQ44162617
Experimental selection of paromomycin and miltefosine resistance in intracellular amastigotes of Leishmania donovani and L. infantumQ46921246
Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites.Q48086647
Establishment and maintenance of sand fly colonies.Q52716429
Evidence of a drug-specific impact of experimentally selected paromomycin and miltefosine resistance on parasite fitness in Leishmania infantum.Q53120855
Intracellular amastigote replication may not be required for successful in vitro selection of miltefosine resistance in Leishmania infantum.Q53541333
Sequential blood meals promote Leishmania replication and reverse metacyclogenesis augmenting vector infectivity.Q54253014
Functional role of evolutionarily highly conserved residues, N-glycosylation level and domains of the Leishmania miltefosine transporter-Cdc50 subunitQ56894082
Miltefosine enhances the fitness of a non-virulent drug-resistant Leishmania infantum strainQ58582277
Efficacy of miltefosine in the treatment of visceral leishmaniasis in India after a decade of useQ84100557
P921main subjectPhlebotomus perniciosusQ290277
Leishmania infantumQ1950789
Lutzomyia longipalpisQ14688675
P304page(s)1-7
P577publication date2019-09-10
P1433published inInternational Journal for Parasitology: Drugs and Drug ResistanceQ20181953
P1476titleImpaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis
P478volume11

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