In vitro metabolic zonation through oxygen gradient on a chip

scientific article published on 19 September 2019

In vitro metabolic zonation through oxygen gradient on a chip is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41598-019-49412-6
P932PMC publication ID6753109
P698PubMed publication ID31537830

P50authorGiovanni G. GiobbeQ51491154
Camilla LuniQ51491174
Nicola ElvassoreQ88210953
P2093author name stringAlessandro Zambon
Onelia Gagliano
Gabriele Grassi
Annarosa Floreani
Federica Tonon
P2860cites workAn in vitro hepatic zonation model with a continuous oxygen gradient in a microdevice.Q51680100
Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes.Q55384558
Design of a stirred multiwell bioreactor for expansion of CD34+ umbilical cord blood cells in hypoxic conditionsQ84366196
Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver AcinusQ87969668
Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic deviceQ30492227
Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systemsQ30494364
Generation of oxygen gradients with arbitrary shapes in a microfluidic deviceQ30494927
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cellsQ33457167
Liver zonation: Novel aspects of its regulation and its impact on homeostasisQ33886995
Soft lithography in biology and biochemistryQ34304610
In vitro zonation and toxicity in a hepatocyte bioreactorQ34375235
Metabolic zonation of the liver: regulation and implications for liver functionQ35417325
Oxygen: modulator of physiological and pathophysiological processes in the liverQ36362493
Stochastic model-assisted development of efficient low-dose viral transduction in microfluidicsQ36621974
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signalingQ36843548
Production of hepatocyte-like cells from human pluripotent stem cells.Q36904417
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Q37121662
Transcription dynamics in a physiological process: β-catenin signaling directs liver metabolic zonationQ37633104
Optical methods for sensing and imaging oxygen: materials, spectroscopies and applications.Q38196721
Functional specialization of different hepatocyte populationsQ38663205
The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cellsQ38787362
One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem CellsQ38834246
Zonation of parenchymal and nonparenchymal metabolism in liverQ41138372
Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liverQ42754105
Formation of steady-state oxygen gradients in vitro: application to liver zonationQ46143744
Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.Q49178798
Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems.Q50916795
High-efficiency cellular reprogramming with microfluidics.Q51367877
Functional differentiation of human pluripotent stem cells on a chip.Q51491023
P433issue1
P304page(s)13557
P577publication date2019-09-19
P1433published inScientific ReportsQ2261792
P1476titleIn vitro metabolic zonation through oxygen gradient on a chip
P478volume9

Search more.