γ-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion

scientific article published on 10 March 2020

γ-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.RA119.009577
P932PMC publication ID7170508
P698PubMed publication ID32156704

P50authorErik GylfeQ43049285
Anders HelanderQ52660514
Anders TengholmQ64513022
P2093author name stringPatrick Gilon
Qian Yu
Parvin Ahooghalandari
Bao Khanh Lai
P2860cites workExperimental studies of the influence of vigabatrin on the GABA systemQ24540431
The unique cytoarchitecture of human pancreatic islets has implications for islet cell functionQ24541464
Paracrine and autocrine interactions in the human islet: more than meets the eyeQ26852363
α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)Q28270141
Glucose promotion of GABA metabolism contributes to the stimulation of insulin secretion in β-cellsQ28577461
Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator gamma-hydroxybutyrate (GHB).Q30980440
Evidence for a G protein-coupled gamma-hydroxybutyric acid receptorQ31461224
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cellsQ33231962
Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cellsQ33265073
Cloning and functional characterization of a gamma-hydroxybutyrate receptor identified in the human brainQ33267966
Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeoverQ34244209
Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channelsQ34453916
Characterization of the effects of arginine and glucose on glucagon and insulin release from the perfused rat pancreasQ34467786
Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor systemQ34482509
Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetesQ34756826
Multi-faceted aspects of gamma-hydroxybutyric acid: a neurotransmitter, therapeutic agent and drug of abuseQ34853155
Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMPQ34980521
Glucose regulation of glucagon secretionQ35075947
Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin.Q35196804
Glucose- and hormone-induced cAMP oscillations in α- and β-cells within intact pancreatic isletsQ35797008
Regulation of glucagon secretion in normal and diabetic human islets by γ-hydroxybutyrate and glycineQ36596183
Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cellsQ36796117
Brain glucose sensing and neural regulation of insulin and glucagon secretionQ37913513
Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?Q37913517
GHB receptor targets in the CNS: focus on high-affinity binding sitesQ38165591
Mechanisms for the Specific Properties of γ-Hydroxybutyrate in BrainQ38688873
Submembrane ATP and Ca2+ kinetics in α-cells: unexpected signaling for glucagon secretionQ41015418
Regulation of glucagon release: Effects of insulin on the pancreatic A2-cell of the guinea pigQ41118752
Small Mouse Islets Are Deficient in Glucagon-Producing Alpha Cells but Rich in Somatostatin-Secreting Delta Cells.Q42391383
Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cellsQ42459267
ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.Q43586506
Binding characteristics of gamma-hydroxybutyric acid as a weak but selective GABAB receptor agonistQ48797841
Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells.Q51240535
Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.Q51382315
Glucose controls glucagon secretion by directly modulating cAMP in alpha cellsQ92887387
P407language of work or nameEnglishQ1860
P921main subjectglucagonQ28163629
P577publication date2020-03-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleγ-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion