Morin Alleviates Vincristine-Induced Neuropathic Pain via Nerve protective Effect and Inhibition of NF-κB Pathway in Rats

scientific article published on 22 April 2019

Morin Alleviates Vincristine-Induced Neuropathic Pain via Nerve protective Effect and Inhibition of NF-κB Pathway in Rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10571-019-00679-3
P698PubMed publication ID31011938

P2093author name stringJing Shi
Ke Jiang
Jinshan Shi
P2860cites workPrevention and Treatment for Chemotherapy-Induced Peripheral Neuropathy: Therapies Based on CIPN Mechanisms.Q48106419
Morin Suppresses Astrocyte Activation and Regulates Cytokine Release in Bone Cancer Pain Rat ModelsQ48271894
Molecular chemoprevention by morin - A plant flavonoid that targets nuclear factor kappa B in experimental colon cancerQ49916810
Sensitization of TRPV1 receptors by TNF-α orchestrates the development of vincristine-induced pain.Q52649743
Variation in rat sciatic nerve anatomy: implications for a rat model of neuropathic painQ57649272
Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury modelQ58602478
Severe Neuropathic Pain With Concomitant Administration of Vincristine and Posaconazole.Q64922475
Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the ratQ69933970
The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathyQ79816148
Lacosamide has protective disease modifying properties in experimental vincristine neuropathyQ84131110
Saponins of Tribulus terrestris attenuated neuropathic pain induced with vincristine through central and peripheral mechanismQ89228101
Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunitQ24297861
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injuryQ28201682
Ectopic discharge in Abeta afferents as a source of neuropathic painQ28236294
Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neuronsQ28568519
Reduced expression of A-type potassium channels in primary sensory neurons induces mechanical hypersensitivityQ28583649
Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociationQ29615580
Quantitative assessment of tactile allodynia in the rat pawQ29617366
Protective role of morin, a flavonoid, against high glucose induced oxidative stress mediated apoptosis in primary rat hepatocytesQ31086019
Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous systemQ34377314
A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.Q34554719
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Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-L-carnitineQ37209852
Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosisQ37338875
Involvement of inflammatory mediators in neuropathic pain caused by vincristineQ37553189
DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons.Q37692163
Chemotherapy induced peripheral neuropathic painQ38237393
Neuropathic pain: role of inflammation, immune response, and ion channel activity in central injury mechanismsQ38247950
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock.Q40610941
Microtubule disorientation and axonal swelling in unmyelinated sensory axons during vincristine-induced painful neuropathy in rat.Q42541839
Morin exerts neuroprotection via attenuation of ROS induced oxidative damage and neuroinflammation in experimental diabetic neuropathyQ46250407
Dose-related vincristine-induced peripheral neuropathy with unexpected off-therapy worseningQ46395878
P433issue6
P921main subjectNF-κBQ411114
P304page(s)799-808
P577publication date2019-04-22
P1433published inCellular and Molecular NeurobiologyQ2333197
P1476titleMorin Alleviates Vincristine-Induced Neuropathic Pain via Nerve protective Effect and Inhibition of NF-κB Pathway in Rats
P478volume39

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