Amelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration

scientific article published on 27 February 2020

Amelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.TRSL.2020.02.007
P932PMC publication ID7197213
P698PubMed publication ID32160961

P2093author name stringMaria Campos
Graeme Wistow
Joshua Lerner
Jianguo Fan
Katherine Peterson
Dinusha Rajapakse
Sanghamitra Mishra
P2860cites workAmelotin--a Novel Secreted, Ameloblast-specific ProteinQ24296791
The enamel protein amelotin is a promoter of hydroxyapatite mineralizationQ24306809
Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analysesQ24310450
Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA SignalingQ24337081
Protein-mediated enamel mineralizationQ24600888
Atomic-scale compositional mapping reveals Mg-rich amorphous calcium phosphate in human dental enamelQ27332313
Regulation of in vitro vascular calcification by BMP4, VEGF and Wnt3aQ46278853
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degenerationQ47386509
Characterizing Disease Burden and Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration.Q47556983
Molecular Mechanisms Underlying Accelerated Aging by Defects in the FGF23-Klotho System.Q55360714
Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis OutcomesQ57707723
Calcified nodules in retinal drusen are associated with disease progression in age-related macular degenerationQ58602907
RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 familyQ60917574
Correction for Thompson et al., Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eyeQ61727433
Role of the Choroid in Age-related Macular Degeneration: A Current ReviewQ64227512
Synthesis of biomimetic Ca-hydroxyapatite powders at 37 degrees C in synthetic body fluidsQ73936895
Age-related macular degenerationQ81448353
Age-related macular degenerationQ82698020
Correlations in distribution and concentration of calcium, copper and iron with zinc in isolated extracellular deposits associated with age-related macular degenerationQ87698757
Five-Year Outcomes with Anti-Vascular Endothelial Growth Factor Treatment of Neovascular Age-Related Macular Degeneration: The Comparison of Age-Related Macular Degeneration Treatments TrialsQ28049700
Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcificationQ28301225
Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypesQ28306123
Characterization of PHEX endopeptidase catalytic activity: identification of parathyroid-hormone-related peptide107-139 as a substrate and osteocalcin, PPi and phosphate as inhibitorsQ28363247
Functional analysis of alleged NOGGIN mutation G92E disproves its pathogenic relevanceQ31057631
Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE.Q33244627
Abundant lipid and protein components of drusenQ33567644
Association between secreted phosphoprotein-1 (SPP1) polymorphisms and low bone mineral density in womenQ33618811
Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degenerationQ33634096
The role of the retinal pigment epithelium: topographical variation and ageing changesQ34307040
Interaction of complement factor h and fibulin3 in age-related macular degenerationQ34808426
Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eyeQ35062847
Matrix vesicles and calcificationQ35126667
BST2 Mediates Osteoblast Differentiation via the BMP2 Signaling Pathway in Human Alveolar-Derived Bone Marrow Stromal CellsQ36064594
Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complexQ36083881
Function and biological roles of the Dickkopf family of Wnt modulatorsQ36672665
Association studies of ALOX5 and bone mineral density in healthy adultsQ36772430
Genetic polymorphisms of collagen type I α1 chain (COL1A1) gene increase the frequency of low bone mineral density in the subgroup of children with juvenile idiopathic arthritisQ36958163
Age and disease-related structural changes in the retinal pigment epitheliumQ37221512
Role of matrix vesicles in biomineralizationQ37440044
Accumulation of cholesterol and increased demand for zinc in serum-deprived RPE cellsQ37514362
Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture ModelQ37629530
Optical coherence tomography-based observation of the natural history of drusenoid lesion in eyes with dry age-related macular degenerationQ37684465
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cellsQ37714206
The Blood-Retinal Barrier: Structure and Functional SignificanceQ37810007
Global estimates of visual impairment: 2010.Q37963651
The adaptor protein p62/SQSTM1 in osteoclast signaling pathwaysQ37973113
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis.Q38238059
CCN3 increases BMP-4 expression and bone mineralization in osteoblastsQ38332129
Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular DegenerationQ38635651
Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signalingQ38926047
Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathyQ42481006
Immunohistochemical localization of complement regulatory proteins in the human retinaQ42500395
Bruch's membrane aging decreases phagocytosis of outer segments by retinal pigment epithelium.Q42523691
Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.Q45124317
P4510describes a project that usesImageJQ1659584
P921main subjectmacular degenerationQ27429789
P304page(s)45-62
P577publication date2020-02-27
P1433published inTranslational ResearchQ15761127
P1476titleAmelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration
P478volume219

Search more.