Laminin G-like domains: dystroglycan-specific lectins

scientific article published on 06 December 2018

Laminin G-like domains: dystroglycan-specific lectins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.SBI.2018.11.007
P932PMC publication ID6925595
P698PubMed publication ID30530204

P2093author name stringErhard Hohenester
P2860cites workDystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGEQ24301093
Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activityQ24303491
B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycanQ24305043
The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylationQ24305058
Identification of a 2 Mb human ortholog of Drosophila eyes shut/spacemaker that is mutated in patients with retinitis pigmentosaQ24310728
SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan functionQ24316126
EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosaQ24319794
Structure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparinQ24630865
Post-translational Maturation of Dystroglycan Is Necessary for Pikachurin Binding and Ribbon Synaptic LocalizationQ24634095
A stoichiometric complex of neurexins and dystroglycan in brainQ26269938
Crystal structure of the second LNS/LG domain from neurexin 1alpha: Ca2+ binding and the effects of alternative splicingQ26269940
The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrinQ27620848
Distinct requirements for heparin and alpha-dystroglycan binding revealed by structure-based mutagenesis of the laminin alpha2 LG4-LG5 domain pairQ27641994
Structure of a C-type mannose-binding protein complexed with an oligosaccharideQ27642164
Crystal Structure and Cell Surface Anchorage Sites of Laminin  1LG4-5Q27643849
Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-MannosylationQ27703190
Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesisQ28115432
Modulation of agrin function by alternative splicing and Ca2+ bindingQ28249942
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formationQ28507319
LARGE glycans on dystroglycan function as a tunable matrix scaffold to prevent dystrophyQ28512184
Dystroglycan organizes axon guidance cue localization and axonal pathfindingQ28593913
Laminins during muscle development and in muscular dystrophiesQ30654764
Structural basis of laminin binding to the LARGE glycans on dystroglycanQ31121747
The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol β1,4-Xylosyltransferase Required for the Functional Glycosylation of DystroglycanQ32884430
The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan additionQ32884479
Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle.Q34042753
O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.Q34090655
Glycoproteomic characterization of recombinant mouse α-dystroglycanQ34126184
Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection.Q34223029
Differential heparin inhibition of skeletal muscle alpha-dystroglycan binding to lamininsQ34379897
Heparin modulation of laminin polymerizationQ34433284
Glycomic analyses of mouse models of congenital muscular dystrophyQ35065134
A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.Q36232550
Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndromeQ36439344
Laminins in basement membrane assemblyQ36531811
ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycanQ36919737
Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycanQ37200133
Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteinsQ37421355
LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans.Q37472546
Eyes shut homolog is required for maintaining the ciliary pocket and survival of photoreceptors in zebrafishQ37502243
Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entryQ37572562
Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophyQ37737834
Heparan sulfate biosynthesis: regulation and variabilityQ38050077
Biosynthesis and function of chondroitin sulfateQ38115113
Molecular dissection of the alpha-dystroglycan- and integrin-binding sites within the globular domain of human laminin-10.Q38346410
Matriglycan: a novel polysaccharide that links dystroglycan to the basement membrane.Q38424785
Recent insights into structures and functions of C-type lectins in the immune systemQ38545140
Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111.Q38718919
Glycosylation with ribitol-phosphate in mammals: New insights into the O-mannosyl glycanQ39437022
Recent advancements in understanding mammalian O-mannosylationQ40092479
Building synapses: agrin and dystroglycan stick togetherQ40397631
Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage.Q40612428
Mechanistic basis for the recognition of laminin-511 by α6β1 integrin.Q41591759
Dystroglycan binding to α-neurexin competes with neurexophilin-1 and neuroligin in the brain.Q41987606
Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteinsQ42001102
Post-translational disruption of dystroglycan-ligand interactions in congenital muscular dystrophiesQ42524150
Direct Mapping of Additional Modifications on Phosphorylated O-glycans of α-Dystroglycan by Mass Spectrometry Analysis in Conjunction with Knocking Out of Causative Genes for DystroglycanopathyQ42687793
Protein O-Linked Mannose β-1,4-N-Acetylglucosaminyl-transferase 2 (POMGNT2) Is a Gatekeeper Enzyme for Functional Glycosylation of α-DystroglycanQ46448834
Muscular Dystrophy with Ribitol-Phosphate Deficiency: A Novel Post-Translational Mechanism in DystroglycanopathyQ47168266
EYS mutation update: In silico assessment of 271 reported and 26 novel variants in patients with retinitis pigmentosa.Q47380003
Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparin binding domain of lamininQ48249023
Identification of a Post-translational Modification with Ribitol-Phosphate and Its Defect in Muscular DystrophyQ48873234
Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrinQ79165764
O-Mannose and O-N-acetyl galactosamine glycosylation of mammalian α-dystroglycan is conserved in a region-specific mannerQ84558838
Muscular dystrophiesQ86291937
CDP-glycerol inhibits the synthesis of the functional O-mannosyl glycan of α-dystroglycanQ89047205
P304page(s)56-63
P577publication date2018-12-06
P1433published inCurrent Opinion in Structural BiologyQ15758416
P1476titleLaminin G-like domains: dystroglycan-specific lectins
P478volume56

Reverse relations

cites work (P2860)
Q90245857An improved method for culturing myotubes on laminins for the robust clustering of postsynaptic machinery
Q90154126HNK-1 Sulfotransferase modulates α-dystroglycan glycosylation by 3-O-sulfation of glucuronic acid on matriglycan
Q92535136Linker Protein Repair of LAMA2 Dystrophic Neuromuscular Basement Membranes
Q99716328POMK regulates dystroglycan function via LARGE-mediated elongation of matriglycan

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