Compound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib

scientific article published on 01 March 2020

Compound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/JITC-2019-000317
P932PMC publication ID7073790
P698PubMed publication ID32179631

P50authorHui WangQ90370677
P2093author name stringWei Wang
Yang Yang
Feng Wang
Xiaoguang Li
Lin Qiu
Jingquan Li
Qian Ba
Chenghua Yang
Mayu Sun
Rongli You
Wenbo Yao
Zhihu Gao
P2860cites workTargeted and Immune-based Therapies for Hepatocellular CarcinomaQ57055294
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Impact of Viral Status on Survival in Patients Receiving Sorafenib for Advanced Hepatocellular Cancer: A Meta-Analysis of Randomized Phase III TrialsQ39043076
Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approachesQ39067623
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A Natural CCR2 Antagonist Relieves Tumor-associated Macrophage-mediated Immunosuppression to Produce a Therapeutic Effect for Liver CancerQ41348794
Efficacy and Safety of Compound Kushen Injection on Patients with Advanced Colon Cancer: A Meta-Analysis of Randomized Controlled TrialsQ47111707
Can Kushen injection combined with TACE improve therapeutic efficacy and safety in patients with advanced HCC? a systematic review and network meta-analysisQ47135992
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validationQ49735252
Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trialQ50046367
The Therapeutic Efficacy and Safety of Compound Kushen Injection Combined with Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma: An Update Systematic Review and Meta-AnalysisQ26749847
The interaction of anticancer therapies with tumor-associated macrophagesQ27016634
Cancer immunoediting: integrating immunity's roles in cancer suppression and promotionQ27860475
Immune checkpoint blockade: a common denominator approach to cancer therapyQ28083981
Anti-tumor activities of active ingredients in Compound Kushen InjectionQ28088465
Myeloid-derived suppressor cells as regulators of the immune systemQ28131637
The future of immune checkpoint therapyQ28259862
Macrophage plasticity and polarization: in vivo veritasQ29547620
T cell exhaustionQ29620463
Recent advances in hepatocellular carcinoma therapyQ30236010
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.Q34429912
Molecular mechanisms that influence the macrophage m1-m2 polarization balanceQ34583248
Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathwaysQ34619815
Hepatocellular carcinoma: clinical frontiers and perspectivesQ35112053
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.Q35183640
Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathwayQ35560334
Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) MacrophagesQ35646486
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemiaQ36534415
A multicenter randomized controlled open-label trial to assess the efficacy of compound kushen injection in combination with single-agent chemotherapy in treatment of elderly patients with advanced non-small cell lung cancer: study protocol for a raQ36662298
Macrophage polarization in tumour progressionQ37158140
Efficacy of Compound Kushen Injection in Combination with Induction Chemotherapy for Treating Adult Patients Newly Diagnosed with Acute Leukemia.Q37310474
Tumor-associated macrophages: from basic research to clinical applicationQ37671174
Transcriptional control of macrophage polarizationQ38103800
Macrophage plasticity and polarization in liver homeostasis and pathologyQ38151636
Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial designQ38192888
Tumor-associated macrophages: from mechanisms to therapyQ38230880
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue1
P577publication date2020-03-01
P1433published inJournal for Immunotherapy of CancerQ27725163
P1476titleCompound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib
P478volume8

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Q98164533Integrated bioinformatics analysis to decipher molecular mechanism of compound Kushen injection for esophageal cancer by combining WGCNA with network pharmacologycites workP2860

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